bis-(2,3-dihydroxy-propoxy)-methane | 143183-09-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: bis-(2,3-dihydroxy-propoxy)-methane
• 英文别名: Methylenglykol-bis-(β.γ-dioxypropyl)-aether；Methylenglykol-bis-glycerin-aether；Bis-(2,3-dihydroxy-propoxy)-methan；1,2-Propanediol, 3,3a(2)-[methylenebis(oxy)]bis-；3-(2,3-dihydroxypropoxymethoxy)propane-1,2-diol
• CAS: 143183-09-9
• 化学式: C₇H₁₆O₆
• 分子量: 196.2
• InChiKey: RFKSRZIDTYVHLY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  二氯甲烷 、 alkaline earth salt of/the/ methylsulfuric acid 生成 bis-(2,3-dihydroxy-propoxy)-methane
  参考文献：
  名称：

  Hoeland, Justus Liebigs Annalen der Chemie, 1887, vol. 240, p. 241

  摘要：

  DOI：

文献信息

• Functionalized Photoinitiators
  申请人：Dietliker Kurt

  公开号：US20080021126A1

  公开（公告）日：2008-01-24

  The invention relates to novel photoinitiators of formula (I) wherein each of the substituents is given the definition as set forth in the Specification and the claims. The photoinitiators can be used to prepare multifunctional photoinitiators.

  该发明涉及公式（I）中的新型光引发剂，其中每个取代基的定义如规范和索赔中所述。这些光引发剂可用于制备多功能光引发剂。
• Photoinitiators
  申请人：Husler Rinaldo

  公开号：US20070240609A1

  公开（公告）日：2007-10-18

  The invention relates to novel photoinitators of formulae (V), (II), (III), (IV), (V) and (VI) wherein R 1 and R 2 are each independently of the other C 1 -C 8 alkyl; C 1 -C 4 alkyl substituted by OH, C 1 -C 4 alkoxy, —COO(C 1 -C 8 alkyl), (C 1 -C 4 alkyl)-COO—, —CN, benzyl, phenyl or by —N(R 15 )(R 16 ); C 3 -C 6 alkerlyl, benzyl, —CH 2 —C 6 H 4 —(C 1 -C 4 alkyl) or phenyl; or R 1 and R 2 together are unbranched or branched C 2 -C 9 alkylene or C 3 -C 6 -oxa- or -azaalkylene; R 3 , R 4 , R 5 and R 6 are each independently of the others hydrogen, C 1 -C 8 alkyl, C 3 -C 6 alkenyl, benzyl, —CH 2 —C 6 H 4 —(C 1 -C 4 alkyl) or phenyl; R 3 and R 4 together and/or R 5 and R 6 together are unbranched or branched C 2 -C 9 alkylene; A is Cl, Br, —O—R 9 , —N(R 11 )(R 12 ) or —S—R 18 , A′ is —O—, —NH— or —NR 11 —; A″ is Cl, Br, —O—R 9 , —N(R 11 )(R 12 ) or —S—R 18 or hydrogen, X is —O—R 10 or —N(R 13 )(R 14 ), n is an integer from 1 to 10, preferably an integer from 1 to 4, especially 1, 2 or 3; R 7 is a linker; R 8 is a bivalent C 2 -C 3 alkylele radical.

  本发明涉及式（V），（II），（III），（IV），（V）和（VI）的新型光引发剂，其中R1和R2各自独立地为C1-C8烷基；C1-C4烷基被OH，C1-C4烷氧基，-COO（C1-C8烷基），（C1-C4烷基）-COO-，-CN，苯甲基，苯基或-N（R15）（R16）取代；C3-C6烷基，苯甲基，-CH2-C6H4-（C1-C4烷基）或苯基；或R1和R2在一起是直链或支链的C2-C9烷基或C3-C6氧杂或氮杂烷基；R3，R4，R5和R6各自独立地为氢，C1-C8烷基，C3-C6烯基，苯甲基，-CH2-C6H4-（C1-C4烷基）或苯基；R3和R4一起和/或R5和R6一起是直链或支链的C2-C9烷基；A为Cl，Br，-O-R9，-N（R11）（R12）或-S-R18，A'为-O-，-NH-或-NR11-；A''为Cl，Br，-O-R9，-N（R11）（R12）或-S-R18或氢，X为-O-R10或-N（R13）（R14），n为1至10的整数，优选为1至4的整数，特别是1、2或3；R7为连接基；R8为二价的C2-C3烷基基团。
• MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR
  申请人：XIAMEN SINOPEG BIOTECH CO., LTD.

  公开号：US20170312363A1

  公开（公告）日：2017-11-02

  Disclosed are a multifunctionalized polyethylene glycol derivative and a preparation method therefor. The derivative has an H-shaped structure as represented by formula (1) and comprises one linear core LPEG and four PEG branch chains, where n 1 , n 2 , n 3 , and n 4 respectively are the degrees of polymerization of the branch chains, U 1 and U 2 are trivalent branching groups connecting the core LPEG to two of the PEG branch chains, F 1 and F 2 contain a functional group or a protected form R 01 thereof and may or may not contain a branched group G, correspondingly, the number of R 01 is one or more, F 1 and F 2 are either identical or different, any one linking group in the molecule or any linking group formed with an adjacent heteroatom group can either remain stable or be degraded, and any one PEG segment in the molecule is discretely polydispersed or monodispersed. The multifunctional polyethylene glycol is flexible and diverse in terms of branch structures and the lengths of branching arms, has various parameters and performance indicators that are adjustable and easy to control, and has a broad applicability.
• US7462650B2
  申请人：——

  公开号：US7462650B2

  公开（公告）日：2008-12-09
• US7642296B2
  申请人：——

  公开号：US7642296B2

  公开（公告）日：2010-01-05