(4-ethylphenyl)methanesulfonamide | 64732-35-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-ethylphenyl)methanesulfonamide
• 英文别名: 1-(4-ethylphenyl)methanesulfonamide
• CAS: 64732-35-0
• 化学式: C₉H₁₃NO₂S
• mdl: MFCD16156409
• 分子量: 199.274
• InChiKey: OROKGWLRAPYCDG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  68.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (4-ethylphenyl)methanesulfonamide 在 O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate 、 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 190.08h， 以49%的产率得到ethyl 5-cyano-2-methyl-6-[4-({[(3-methylbenzyl)sulfonyl]amino}carbonyl)piperidin-1-yl]nicotinate
  参考文献：
  名称：

  WO2007/8140

  摘要：

  公开号：

文献信息

• [EN] CARBAMATE QUINABACTIN<br/>[FR] QUINABACTINE DE CARBAMATE
  申请人：UNIV CALIFORNIA

  公开号：WO2018017490A1

  公开（公告）日：2018-01-25

  The present invention relates to novel sulfonamide derivatives, to processes and intermediates for preparing them, to plant growth regulator compositions comprising them and to methods of using them for controlling the growth of plants, improving plant tolerance to abiotic stress (including environmental and chemical stresses), inhibiting seed germination and/or safening a plant against phytotoxic effects of chemicals.

  这项发明涉及新型磺胺基衍生物，涉及用于制备它们的工艺和中间体，涉及包含它们的植物生长调节剂组合物，以及使用它们控制植物生长、提高植物对非生物胁迫（包括环境和化学胁迫）的耐受性、抑制种子萌发和/或使植物对化学物质的毒害效应具有安全性的方法。
• New Pyridine Analogues III
  申请人：Antonsson Thomas

  公开号：US20080039437A1

  公开（公告）日：2008-02-14

  The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y 12 inhibitors and as anti-thrombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.

  本发明涉及公式(I)的某些新吡啶类似物，以及制备这些化合物的方法，它们作为P2Y12抑制剂和抗血栓剂等的效用，它们在心血管疾病中作为药物的使用以及含有它们的制药组合物。
• Pyridine Analogues
  申请人：Andersen Soren

  公开号：US20080312208A1

  公开（公告）日：2008-12-18

  The present invention relates to certain new pyridin analogues of Formula (I) Chemical formula should be inserted here. Please see paper copy Formula (I) to processes for preparing such compounds, to their utility as P2Y 12 inhibitors and as anti-thrombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.

  本发明涉及某些新的Formula (I)式吡啶类似物，化学式应在此处插入。请参见纸质副本Formula (I)，以及制备这些化合物的过程，它们作为P2Y12抑制剂和抗血栓剂等的效用，它们在心血管疾病中作为药物的用途以及含有它们的制药组合物。
• NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION
  申请人：Blatt Lawrence M.

  公开号：US20120208995A1

  公开（公告）日：2012-08-16

  The embodiments provide compounds of the general Formulae I through general Formula VIII, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

  本实施例提供了一般式I至一般式VIII的化合物，以及包括药物组合物在内的组合物。实施例还提供了治疗方法，包括治疗丙型肝炎病毒感染和治疗肝纤维化的方法，通常涉及向需要的个体施用所述化合物或组合物的有效量。
• Cellulose acetate wood filler compositions
  申请人：CELANESE INTERNATIONAL CORPORATION

  公开号：US10119037B2

  公开（公告）日：2018-11-06

  A cellulose acetate wood filler composition comprises a binder composition and a filler. The binder compositions comprise cellulose acetate, a plasticizer, and at least one organic solvent. The binder compositions may be substantially free, e.g., free of tackifiers. The wood filler compositions may be used in a method of filling a cavity in a substrate. The method comprises applying the wood filler composition to an inner surface of the substrate.

  醋酸纤维素木材填料组合物由粘结剂组合物和填料组成。粘合剂组合物包括醋酸纤维素、增塑剂和至少一种有机溶剂。粘合剂组合物可以基本上不含增粘剂。木材填充物组合物可用于填充基材空腔的方法中。该方法包括将木材填充剂组合物涂在基材的内表面。