[3]-paradol | 53172-01-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: [3]-paradol
• 英文别名: 1-(4-Hydroxy-3-methoxyphenyl)heptan-3-one
• CAS: 53172-01-3
• 化学式: C₁₄H₂₀O₃
• 分子量: 236.311
• InChiKey: WKCSWVXARWGWMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-己酮 在 palladium on activated charcoal 四氢吡咯 、 氢气 、 溶剂黄146 作用下， 生成 [3]-paradol
  参考文献：
  名称：

  辛辣的化合物。第一部分。改进的对位异构体（烷基4-羟基-3-甲氧基苯乙基酮）的合成及其辛辣度评估

  摘要：

  同源系列的11个对位的多巴酚，其中一个[6]对位的多酚（正庚基4-羟基-3-甲氧基苯乙基酮）天然存在于砂仁砂仁（Zingiberaceae）的种子中（也称为天堂谷物） ，几内亚胡椒或Melegueta胡椒）已通过一种改良方法合成。该系列介绍了包括g​​lc行为在内的物理特性和刺激性评估实验。

  DOI：

  10.1039/p19720003001

文献信息

• USE OF GINGERONE OR DERIVATIVES THEREOF FOR REDUCING OR DELAYING THE SIGNS OF SKIN AGEING
  申请人：L'OREAL

  公开号：US20180161257A1

  公开（公告）日：2018-06-14

  The present invention relates to the cosmetic use of at least one compound of general formula (I): in which: R 1 represents a methyl or ethyl radical; R 2 represents a hydrogen atom or a methyl or ethyl radical; R 3 represents a linear C 1 -C 6 or branched C 3 -C 6 alkyl radical, or a linear C 2 -C 6 or branched C 3 -C 6 alkenyl radical; and X represents ═O or —OH, as an agent for reducing and/or delaying the signs of skin ageing.

  本发明涉及将通式(I)的至少一个化合物用于化妆品中： 其中： R1代表甲基或乙基基团； R2代表氢原子或甲基或乙基基团； R3代表线性C1-C6或支链C3-C6烷基基团，或线性C2-C6或支链C3-C6烯基基团； X代表═O或—OH， 作为一种减少和/或延缓皮肤衰老迹象的药剂。
• PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND; USE OF SAID COMPOUND FOR INCREASING THE SUN PROTECTION FACTOR
  申请人：L'OREAL

  公开号：EP3281620A1

  公开（公告）日：2018-02-14

  The present invention relates to a fluid composition intended for protecting the skin and/or hair against ultraviolet radiation, characterized by the fact that it comprises, in a cosmetically acceptable aqueous support, at least: (a) one photoprotective system capable of screening out UV radiation; and (b) one 2-alkoxy-4-alkyl ketone phenol compound. The present invention also relates to the use of a 2-alkoxy-4-alkyl ketone phenol compound in a composition comprising, in a cosmetically acceptable medium, at least one photoprotective system capable of screening out UV radiation.

  本发明涉及一种用于保护皮肤和/或头发免受紫外线辐射的流体组合物，其特征在于，该组合物在化妆品可接受的水性支持物中至少包括 (a) 一种能屏蔽紫外线辐射的光保护系统；和 (b) 一种 2-烷氧基-4-烷基酮酚化合物。 本发明还涉及 2-烷氧基-4-烷基酮酚化合物在组合物中的使用，该组合物包含在化妆品可接受的介质中的至少一种能够屏蔽紫外线辐射的光保护体系。
• USE OF ETHYL GINGERONE OR DERIVATIVES THEREOF FOR REDUCING OR DELAYING THE SIGNS OF SKIN AGEING
  申请人：L'Oréal

  公开号：EP2694025B1

  公开（公告）日：2018-04-25
• COMPOSITION, USE, AND PRESERVATION METHOD
  申请人：Dalko Maria

  公开号：US20120269739A1

  公开（公告）日：2012-10-25

  The invention relates to a cosmetic, pharmaceutical, dermatological, nutraceutical or oral cosmetic composition having, as main preserving system, a mild preserving system formed from compounds with a broad antimicrobial spectrum, which have only one pKa, the said pKa being greater than or equal to 10, the said mild preserving system being present in a content strictly greater than or equal to 1% by weight relative to the weight of the said composition. The invention also relates to the use, in a cosmetic, dermatological or pharmaceutical composition, of at least one compound of formula (I), as a preserving agent:
• US8765101B2
  申请人：——

  公开号：US8765101B2

  公开（公告）日：2014-07-01