c(TT) | 25324-45-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: c(TT)
• 英文别名: O^{3'_,O5'''_;O5'_,O3'''}-bis-hydroxyphosphoryl-di-thymidine；O^{3'_,O5'''_;O5'_,O3'''}-Bis-hydroxyphosphoryl-di-thymidin；1-[(1S,6R,8R,10S,15R,17R)-3,12-dihydroxy-17-(5-methyl-2,4-dioxopyrimidin-1-yl)-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]-5-methylpyrimidine-2,4-dione；1-[(1S,6R,8R,10S,15R,17R)-3,12-dihydroxy-17-(5-methyl-2,4-dioxopyrimidin-1-yl)-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3λ5,12λ5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]-5-methylpyrimidine-2,4-dione
• CAS: 25324-45-2
• 化学式: C₂₀H₂₆N₄O₁₄P₂
• 分子量: 608.392
• InChiKey: ZWGQVAFNPPECEA-KPRKPIBOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.2
• 重原子数：
  40
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  229
• 氢给体数：
  4
• 氢受体数：
  14

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 c(TT)
  参考文献：
  名称：

  Making cyclic RNAs easily available

  摘要：

  A simple solid-phase procedure allows cyclic oligoribonucleotides to be obtained as long as the linear precursor attached to the support has a 2′-deoxyribonucleoside or a 2′-O-methylribonucleoside at the 3′-end.

  DOI：

  10.1039/a904851k

文献信息

• Studies on Polynucleotides. II.¹ The Synthesis and Characterization of Linear and Cyclic Thymidine Oligonucleotides²
  作者：G. M. Tener、H. G. Khorana、R. Markham、E. H. Pol

  DOI：10.1021/ja01556a017

  日期：1958.12
• Studies on Polynucleotides. VI.¹ Experiments on the Chemical Polymerization of Mononucleotides. Oligonucleotides Derived from Thymidine-3' Phosphate²
  作者：A. F. Turner、H. G. Khorana

  DOI：10.1021/ja01526a051

  日期：1959.9