catharsitoxin A | 376587-10-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 英文名称: catharsitoxin A
• 英文别名: 3-Ethyl-2-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine
• CAS: 376587-10-9
• 化学式: C₁₀H₁₆N₂
• 分子量: 164.25
• InChiKey: OSLLDMMZAKJNKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  6-甲氧基-2,3,4,5-四氢吡啶 在 ammonium acetate 、 potassium bromide 作用下， 以 溶剂黄146 、 N,N-二甲基甲酰胺 为溶剂， 反应 32.0h， 生成 catharsitoxin A
  参考文献：
  名称：

  Catharsitoxins from the Chinese remedy qiung laug

  摘要：

  Novel imidazole compounds catharsitoxins A, B, C, D, E and F, were isolated from the Chinese remedy qiung laug. Their structures were determined by 2D NMR. To confirm their structures and to ensure an adequate supply for further biological studies, catharsitoxins A and D were synthesized. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)01468-x

文献信息

• Catharsitoxins from the Chinese remedy qiung laug
  作者：Kiyotake Suenaga、Hiroki Shimogawa、Satoru Nakagawa、Daisuke Uemura

  DOI：10.1016/s0040-4039(01)01468-x

  日期：2001.10

  Novel imidazole compounds catharsitoxins A, B, C, D, E and F, were isolated from the Chinese remedy qiung laug. Their structures were determined by 2D NMR. To confirm their structures and to ensure an adequate supply for further biological studies, catharsitoxins A and D were synthesized. (C) 2001 Elsevier Science Ltd. All rights reserved.