1,3-bis<<7-oxo-4-(benzyloxycarbonyl)-2,2,6-trimethyl-1,4-diazabicyclo<3.2.0>hept-6-yl>oxy>propane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3-bis<<7-oxo-4-(benzyloxycarbonyl)-2,2,6-trimethyl-1,4-diazabicyclo<3.2.0>hept-6-yl>oxy>propane
• 英文别名: Benzyl 6-(3-((4-((benzyloxy)carbonyl)-2,2,6-trimethyl-7-oxo-1,4-diazabicyclo[3.2.0]hept-6-yl)oxy)propoxy)-2,2,6-trimethyl-7-oxo-1,4-diazabicyclo[3.2.0]heptane-4-carboxylate；benzyl 2,2,6-trimethyl-7-oxo-6-[3-[(2,2,6-trimethyl-7-oxo-4-phenylmethoxycarbonyl-1,4-diazabicyclo[3.2.0]heptan-6-yl)oxy]propoxy]-1,4-diazabicyclo[3.2.0]heptane-4-carboxylate
• 化学式: C₃₅H₄₄N₄O₈
• 分子量: 648.756
• InChiKey: SQWVGUGVYZDKBN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  47
• 可旋转键数：
  12
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  118
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1,3-bis<<7-oxo-4-(benzyloxycarbonyl)-2,2,6-trimethyl-1,4-diazabicyclo<3.2.0>hept-6-yl>oxy>propane 在 palladium on activated charcoal 氢气 、 三乙胺 作用下， 以 甲醇 为溶剂， 反应 0.5h， 生成 1,3-bis<<7-oxo-2,2,6-trimethyl-1,4-diazabicyclo<3.2.0>hept-6-yl>oxy>propane 、 1,3-bis<<7-oxo-2,2,6-trimethyl-1,4-diazabicyclo<3.2.0>hept-6-yl>oxy>propane
  参考文献：
  名称：

  Synthesis and Metal Complexation Reactions of Bis-Dioxocyclams from Photochemical Reaction of Bis-Chromium Alkoxycarbene Complexes with Imidazolines

  摘要：

  Bis-chromium alkoxycarbene complexes, bridged via the alkoxy groups, underwent photochemical cycloaddition to protected imidazolines to give protected bis-azapenams. Deprotection followed by treatment with acid produced bis-dioxocyclams bridged top and bottom with four-, five-, six-, and twelve-atom alpha,omega-diol linkages. These bis-dioxocyclam ligands formed mono- and bis-nickel(II) complexes. The five-atom bridged system (-O(CH2)(3)O-) was characterized by X-ray crystallography and had a number of unusual features.

  DOI：

  10.1021/ja00117a007