1-(碘甲基)-吡咯烷 | 342401-48-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 中文名称: 1-(碘甲基)-吡咯烷
• 英文名称: 1-(Iodomethyl)pyrrolidine
• CAS: 342401-48-3
• 化学式: C₅H₁₀IN
• 分子量: 211.04
• InChiKey: IRDXQTMQWOPUMQ-UHFFFAOYSA-N

物化性质

• 沸点：
  180.5±23.0 °C(Predicted)
• 密度：
  1.763±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  7
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  喹啉 、 1-(碘甲基)-吡咯烷 生成 1-(pyrrolidin-1-ylmethyl)quinolin-1-ium iodide
  参考文献：
  名称：

  10.14233/ajchem.2024.31574

  摘要：

  Dicationic ionic liquids (DILs) have sparked a lot of attention due to their high melting point, better solubility, thermal stability and facilitated the creation of molecules with precise functions and application requirements. Dicationic ionic liquids have garnered significant attention in the field of green synthesis media due to their diverse cationic groups. In this work, four environmental friendly unsymmetrical dicationic room temperature ionic liquids with different cationic were synthesized by a simple neutralization process. The structure of the newly synthesized DILs was confirmed by FTIR, 1H NMR, 13C NMR, elemental and ESI-HRMS spectral analyses. All the synthesized DILs were also screened for antifungal, anti-inflammatory and antioxidant activities. When compared the microbial activities of DILs of different cations, the results showed that all the synthesized DILs were effective against Candida albicans fungi and had good scavenging activity in DPPH and against protein denaturation with their respective standards. Because of their sulphonic acid and hydroxyl groups in DIL-III and D-IV were the most promising candidates for antifungal, anti-inflammatory and antioxidant properties.

  DOI：

  10.14233/ajchem.2024.31574
• 作为产物：
  描述：

  N-cyclohexyl-4-methyl-N-(pyrrolidin-1-ylmethyl)benzenesulfinamide 、 碘甲烷 生成 1-(碘甲基)-吡咯烷
  参考文献：
  名称：

  WENSCHUH E.; GUENTHER W.; PLEWINSKI K., J. PRAKT. CHEM., 1977, 319, NO 2, 297-304

  摘要：

  DOI：

文献信息

• WENSCHUH E.; GUENTHER W.; PLEWINSKI K., J. PRAKT. CHEM., 1977, 319, NO 2, 297-304
  作者：WENSCHUH E.、 GUENTHER W.、 PLEWINSKI K.

  DOI：——

  日期：——
• 10.14233/ajchem.2024.31574
  作者：Sathya、Rajathi

  DOI：10.14233/ajchem.2024.31574

  日期：——

  Dicationic ionic liquids (DILs) have sparked a lot of attention due to their high melting point, better solubility, thermal stability and facilitated the creation of molecules with precise functions and application requirements. Dicationic ionic liquids have garnered significant attention in the field of green synthesis media due to their diverse cationic groups. In this work, four environmental friendly unsymmetrical dicationic room temperature ionic liquids with different cationic were synthesized by a simple neutralization process. The structure of the newly synthesized DILs was confirmed by FTIR, 1H NMR, 13C NMR, elemental and ESI-HRMS spectral analyses. All the synthesized DILs were also screened for antifungal, anti-inflammatory and antioxidant activities. When compared the microbial activities of DILs of different cations, the results showed that all the synthesized DILs were effective against Candida albicans fungi and had good scavenging activity in DPPH and against protein denaturation with their respective standards. Because of their sulphonic acid and hydroxyl groups in DIL-III and D-IV were the most promising candidates for antifungal, anti-inflammatory and antioxidant properties.