2-formylbenzenesulphonate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-formylbenzenesulphonate
• 英文别名: 2-formylbenzenesulfonate(1-)；2-formylbenzenesulfonate
• 化学式: C₇H₅O₄S
• 分子量: 185.18
• InChiKey: SHHKMWMIKILKQW-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  82.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,1'-(cyclohexan-1,4-diyl)bis(2-benzylpyridine-1ium) dibromide 、 2-formylbenzenesulphonate 在 potassium hydroxide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 生成 disodium 2-((E)-1-phenyl-2-(2-sulphonatophenyl)vinyl)-1-(4-(2-(E-1-phenyl-2-(2-sulphonato)vinyl)pyridine-1-ium-1-yl)-cyclohexyl)pyridine-1-ium-3-ide dibromide
  参考文献：
  名称：

  合成了一些新颖的二甲胺，双-二甲胺花青染料和八甲亚甲菁花青染料，它们具有针对（HepG2），（Hela），（MCF-7），（MIA），（SN12C）和（H358）细胞系的有前途的生物学潜能。

  摘要：

  通过吡啶盐1与某些不同醛的反应，成功地一步法合成了二甲胺花青染料，双二甲胺花青染料和二十二甲胺花青染料2-10的两组分，希望获得具有增强的生物效能的化合物，作为针对自发性肝的抗肿瘤剂（HepG2 ），宫颈（Hela），乳房（MCF-7），胰腺（MIA），肾脏（SN12C）和肺（H358）。通过结构活性关系（SAR）反映了替代药物对肿瘤细胞的影响。在这些染料中，异花青素花青染料8对所有测试的细胞系均表现出优异的活性。通过光谱学和元素分析鉴定并强调了新目的地药物。

  DOI：

  10.1016/j.bmcl.2018.04.032
• 作为产物：
  描述：

  4,4'-bis(2-sulfostyryl)biphenyl 在 dioxide titanium 作用下， 生成 2-formylbenzenesulphonate 、 monocarboxybenzenesulfonate 、 2-Sulfonatobenzoate 、 [1,1'-biphenyl]-4,4'-dicarboxylate
  参考文献：
  名称：

  Photodegradation of 4,4‘-Bis(2-sulfostyryl)biphenyl (DSBP) on Metal Oxides Followed by in Situ ATR-FTIR Spectroscopy

  摘要：

  Photodegradation on soil and mineral surfaces is an important pathway for the transformation of recalcitrant pollutants in the atmosphere and on terrestrial surfaces. Monitoring degradation on surfaces under controlled conditions without intrusive methods, however, remains a challenge. Here, we report in situ measurements of the photodegradation of 4,4'-bis(2-sulfostyryl)biphenyl (DSBP), a fluorescent whitening agent used in laundry detergents, on the surfaces of metal oxides under conditions of controlled humidity using attenuated total reflectance infrared spectroscopy (ATR-FTIR). A ZnSe ATR crystal was coated with 1-5 mu m thick layers of high specific surface area hematite, delta-alumina, lepidocrocite, rutile, and anatase. The 0.4 mg oxide layers were spiked with 20 nmol of (E, E)-DSBP and illuminated with 365 nm light at 25 degrees C and 88% relative humidity. Extensive degradation was observed on rutile and anatase due to the photocatalytic action of the TiO2 semiconductor particles. Degradation on alumina, hematite, and lepidocrocite, on the other hand, was slower and occurred primarily through the direct photodegradation of adsorbed DSBP. For hematite and lepidocrocite, light absorption by the oxide layer reduced the degradation rate by reducing the amount of light available to DSBP. Implications for the photodegradation reactions,of environmental contaminants on sails are discussed.

  DOI：

  10.1021/es981226t

文献信息

• Synthesis of some novel dimethine, bis-dimethine cyanine dyes and octacosamethine cyanine dyes endowed with promising biological potency against (HepG2), (Hela), (MCF-7), (MIA), (SN12C) and (H358) cell lines
  作者：Rasha E. El-Mekawy、A.A. Fadda

  DOI：10.1016/j.bmcl.2018.04.032

  日期：2018.6

  Successfully, one step two component synthesis of dimethine cyanine dyes, bis-dimethine cyanine dyes and icosamethine cyanine dyes 2-10via reaction of pyridinium salt 1 with some different aldehydes hope to obtain these compounds with enhanced biological potency as antitumor agents against spontaneous liver (HepG2), cervical (Hela), breast (MCF-7), pancreas (MIA), kidney (SN12C) and lung (H358). The

  通过吡啶盐1与某些不同醛的反应，成功地一步法合成了二甲胺花青染料，双二甲胺花青染料和二十二甲胺花青染料2-10的两组分，希望获得具有增强的生物效能的化合物，作为针对自发性肝的抗肿瘤剂（HepG2 ），宫颈（Hela），乳房（MCF-7），胰腺（MIA），肾脏（SN12C）和肺（H358）。通过结构活性关系（SAR）反映了替代药物对肿瘤细胞的影响。在这些染料中，异花青素花青染料8对所有测试的细胞系均表现出优异的活性。通过光谱学和元素分析鉴定并强调了新目的地药物。
• Photodegradation of 4,4‘-Bis(2-sulfostyryl)biphenyl (DSBP) on Metal Oxides Followed by in Situ ATR-FTIR Spectroscopy
  作者：Janet M. Kesselman-Truttmann、Stephan J. Hug

  DOI：10.1021/es981226t

  日期：1999.9.1

  Photodegradation on soil and mineral surfaces is an important pathway for the transformation of recalcitrant pollutants in the atmosphere and on terrestrial surfaces. Monitoring degradation on surfaces under controlled conditions without intrusive methods, however, remains a challenge. Here, we report in situ measurements of the photodegradation of 4,4'-bis(2-sulfostyryl)biphenyl (DSBP), a fluorescent whitening agent used in laundry detergents, on the surfaces of metal oxides under conditions of controlled humidity using attenuated total reflectance infrared spectroscopy (ATR-FTIR). A ZnSe ATR crystal was coated with 1-5 mu m thick layers of high specific surface area hematite, delta-alumina, lepidocrocite, rutile, and anatase. The 0.4 mg oxide layers were spiked with 20 nmol of (E, E)-DSBP and illuminated with 365 nm light at 25 degrees C and 88% relative humidity. Extensive degradation was observed on rutile and anatase due to the photocatalytic action of the TiO2 semiconductor particles. Degradation on alumina, hematite, and lepidocrocite, on the other hand, was slower and occurred primarily through the direct photodegradation of adsorbed DSBP. For hematite and lepidocrocite, light absorption by the oxide layer reduced the degradation rate by reducing the amount of light available to DSBP. Implications for the photodegradation reactions,of environmental contaminants on sails are discussed.

表征谱图