2-(1-propenyl)pyrazine | 34413-32-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-(1-propenyl)pyrazine
• 英文别名: propenylpyrazine；Methylvinylpyrazine；2-prop-1-enylpyrazine
• CAS: 34413-32-6
• 化学式: C₇H₈N₂
• 分子量: 120.154
• InChiKey: ZBHYPERRXYKXGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 synthetic air 作用下， 生成 2-(1-propenyl)pyrazine
  参考文献：
  名称：

  Complete Study of the Pyrolysis and Gasification of Scrap Tires in a Pilot Plant Reactor

  摘要：

  The pyrolysis and gasification of tires was studied in a pilot plant reactor provided with a system for condensation of semivolatile matter. The study comprises experiments at 450, 750, and 1000 degreesC both in nitrogen and 10% oxygen atmospheres. Analysis of all the products obtained (gases, liquids, char, and soot) are presented. In the gas phase only methane and benzene yields increase with temperature until 1000 degreesC. In the liquids the main components are styrene, limonene, and isoprene. The solid fraction (including soot) increases with temperature. Zinc content of the char decreases with increasing temperature.

  DOI：

  10.1021/es034608u

文献信息

• [EN] NEW TETRACYCLIC COMPOUNDS<br/>[FR] NOUVEAUX COMPOSÉS TÉTRACYCLIQUES
  申请人：MEDIVATION TECHNOLOGIES INC

  公开号：WO2009055828A1

  公开（公告）日：2009-04-30

  This disclosure relates to new tetracyclic compounds that may be used to modulate a histamine receptor in an individual. The compounds in one embodiment are tetracyclic [4,3- b]indoles. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.

  这项披露涉及可能用于调节个体组织胺受体的新四环化合物。在一个实施例中，这些化合物是四环[4,3- b]吲哚类化合物。此外还提供了包含这些化合物的药物组合物，以及使用这些化合物进行各种治疗应用的方法，包括治疗认知障碍、精神障碍、神经递质介导的障碍和/或神经元障碍。
• POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450
  申请人：University of Kentucky Research Foundation

  公开号：US20210246109A1

  公开（公告）日：2021-08-12

  Inhibitors of the enzyme cytochrome P450 (CYP), including 1B1 (CYP1B1), 1A1 (CYP1A1) and 19A1 (CYP19A1) are provided, and are useful in medical applications. Disclosed are highly potent and selective compounds that can be used in chemoprevention to ameliorate malignant changes induced by CYP, or to aid in treatment, including restoration of chemotherapeutic efficacy.

  本文提供了细胞色素P450 (CYP) 酶的抑制剂，包括1B1 (CYP1B1)，1A1 (CYP1A1) 和19A1 (CYP19A1)，这些抑制剂在医学应用中非常有用。本文还披露了高效、选择性的化合物，可用于化学预防，以减轻CYP引起的恶性变化，或用于治疗，包括恢复化疗的疗效。
• Tetracyclic compounds
  申请人：HUNG David T.

  公开号：US20090239854A1

  公开（公告）日：2009-09-24

  This disclosure relates to new tetracyclic compounds that may be used to modulate a histamine receptor in an individual. The compounds in one embodiment are tetracyclic [4,3-b]indoles. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.

  本公开涉及新的四环化合物，可用于调节个体中的组胺受体。在一种实施例中，该化合物为四环[4,3-b]吲哚。还提供了包含该化合物的药物组合物，以及使用该化合物进行各种治疗应用的方法，包括治疗认知障碍、精神障碍、神经递质介导的障碍和/或神经元障碍。
• TETRACYCLIC COMPOUNDS
  申请人：MEDIVATION TECHNOLOGIES, INC.

  公开号：US20140194414A1

  公开（公告）日：2014-07-10

  This disclosure relates to new tetracyclic compounds that may be used to modulate a histamine receptor in an individual. The compounds in one embodiment are tetracyclic[4,3-b]indoles. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.

  本文涉及新的四环化合物，可用于调节个体中的组胺受体。在其中一种实施方式中，这些化合物是四环[4,3-b]吲哚。还提供了包含这些化合物的制药组合物，以及使用这些化合物进行各种治疗应用的方法，包括治疗认知障碍、精神障碍、神经递质介导的障碍和/或神经元障碍。
• [EN] GUM COMPOSITION CONTAINING DISPERSED POROUS BEADS CONTAINING ACTIVE CHEWING GUM INGREDIENTS AND METHOD
  申请人：WM. WRIGLEY JR. COMPANY

  公开号：WO1990007882A1

  公开（公告）日：1990-07-26

  (EN) A chewing gum that contains porous polymeric beads impregnated with active gum ingredients together with a method of making such a chewing gum.(FR) Sont décrits une gomme à mâcher contenant des grains polymères poreux imprégnés d'ingrédients actifs de gomme ainsi qu'un procédé pour sa fabrication.

  一种含胶糖果，其糖果中含有多孔聚合物颗粒，这种颗粒浸渍了活性胶原成分，以及制备这种含胶糖果的方法。 **法文本对照：** Ensemble une tablette à pAdvertiser gan 佞但我们发现你的文本可能需要更正或更正后的翻译。 请注意，提供法文本 When you say "gum" in English, it directly translates to "胶原" in Chinese, but also "软糖" would be a better translation for "containing gums". 我们需要确保术语的准确性和一致性。请提供更正后的文本以便更好地完成翻译工作。