1-[6-(2-氧代吡咯烷-1-基)己基]吡咯烷-2-酮 | 34751-43-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 中文名称: 1-[6-(2-氧代吡咯烷-1-基)己基]吡咯烷-2-酮
• 英文名称: N,N'-Hexamethylen-bis-(2-pyrrolidon)
• 英文别名: 1,1'-hexane-1,6-diyl-bis-pyrrolidin-2-one；1,1'-hexanediyl-bis-pyrrolidin-2-one；1,1'-Hexandiyl-bis-pyrrolidin-2-on；1,1'-hexamethylenebis(pyrrolidin-2-one)；1,6-Bis-(1-azacyclopentan-2-onyl)hexane；hexamethylene bis (2-pyrrolidone)；1-[6-(2-oxopyrrolidin-1-yl)hexyl]pyrrolidin-2-one
• CAS: 34751-43-4
• 化学式: C₁₄H₂₄N₂O₂
• 分子量: 252.357
• InChiKey: CGJZPGDXEGFRAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2933790090

反应信息

• 作为反应物：
  描述：

  1-[6-(2-氧代吡咯烷-1-基)己基]吡咯烷-2-酮 在 barium dihydroxide 作用下， 生成 4,4'-hexanediyldiamino-di-butyric acid
  参考文献：
  名称：

  Reppe et al., Justus Liebigs Annalen der Chemie, 1955, vol. 596, p. 1,215

  摘要：

  DOI：
• 作为产物：
  描述：

  2-吡咯烷酮 生成 1-[6-(2-氧代吡咯烷-1-基)己基]吡咯烷-2-酮
  参考文献：
  名称：

  RAJAKHYAKSHA, VITHAL, J.

  摘要：

  DOI：

文献信息

• Vehicle composition containing 1-substituted azacyclononan-2-ones
  申请人：Nelson Research & Development Company

  公开号：US04415563A1

  公开（公告）日：1983-11-15

  Compositions useful for carrying physiologically active agents such as therapeutic agents through skin and other body membranes comprising the agent and an effective, non-toxic amount of a compound having the structural formula ##STR1## wherein R' is H or a lower alkyl group, m is 3-7, N is 0-17 and R is --CH.sub.3, phenyl or substituted phenyl or ##STR2## with the proviso that if m is 3 and R is --CH.sub.3, then n is not 0-6.

  用于携带生理活性剂如治疗剂通过皮肤和其他体膜的组合物，包括该剂和结构式##STR1##中具有有效的、无毒的化合物，其中R'为H或低碳基团，m为3-7，N为0-17，而R为--CH.sub.3，苯基或取代苯基或##STR2##，但如果m为3且R为--CH.sub.3，则n不为0-6。
• Vehicle composition containing 1-substituted azacycloalkan-2-ones
  申请人：Nelson Research & Development Company

  公开号：US04424210A1

  公开（公告）日：1984-01-03

  Compositions useful for carrying physiologically active agents such as therapeutic agents through skin and other body membranes comprising the agent and an effective, non-toxic amount of a compound having the structural formula ##STR1## wherein R' is H or a lower alkyl group, m is 3-7, N is 0-17 and R is --CH.sub.3, phenyl or substituted phenyl or ##STR2## with the proviso that if m is 3 and R is --CH.sub.3, then n is not 0-6.

  用于携带生理活性剂如治疗剂通过皮肤和其他身体膜的组成物包括该剂和一个有效的、无毒的化合物，其具有结构式 ##STR1## 其中R'是H或较低的烷基，m为3-7，N为0-17，R为-CH.sub.3，苯基或取代苯基或 ##STR2## 前提是如果m为3且R为-CH.sub.3，则n不是0-6。
• Vehicle composition containing 1-substituted azacyclopentan-2-ones
  申请人：Nelson Research & Development Company

  公开号：US04444762A1

  公开（公告）日：1984-04-24

  Compositions useful for carrying physiologically active agents such as therapeutic agents through skin and other body membranes comprising the agent and an effective, non-toxic amount of a compound having the structural formula ##STR1## wherein R' is H or a lower alkyl group, m is 3-7, N is 0-17 and R is --CH.sub.3, phenyl or substituted phenyl or ##STR2## with the proviso that if m is 3 and R is --CH.sub.3, then n is not 0-6.

  此处提供的是用于携带生理活性剂，如治疗剂，穿过皮肤和其他身体膜的组合物，其中包括该剂和具有结构式##STR1##的化合物的有效、无毒量，其中R'为H或较低的烷基，m为3-7，N为0-17，R为--CH.sub.3，苯基或取代苯基，或##STR2##，但如果m为3且R为--CH.sub.3，则n不为0-6。
• Method for improved plant pest control
  申请人：Whitby Research Incorporated

  公开号：EP0077078A1

  公开（公告）日：1983-04-20

  The disclosure describes a method for improved plant pest control comprising contacting a plant or plant pest with a composition comprising an effective amount of a plant pesticide and an effective delivery enhancing amount of compound having the structural formula wherein R' is H or a lower alkyl group having 1-4 carbon atoms, m is 3-7, n is 0-17 and R is or where R" is H or halogen, with the proviso that if m is 3 and R is CH3, then n is 5-17. Typical plant pesticides include insecticides, fungicides, herbicides, rodenticides. nematicides, molluscicides and acaricides. The preferred penetration enhancing compound is 1-n-dodecylaza cycloheptan-2-one.

  本公开描述了一种改进植物害虫控制的方法，该方法包括用一种组合物与植物或植物害虫接触，该组合物包含有效量的植物杀虫剂和有效递送增强量的化合物，其结构式为 其中 R' 是 H 或具有 1-4 个碳原子的低级烷基，m 是 3-7，n 是 0-17，R 是 或 其中 R "为 H 或卤素，但如果 m 为 3 且 R 为 CH3，则 n 为 5-17。 典型的植物杀虫剂包括杀虫剂、杀真菌剂、除草剂、杀鼠剂、杀线虫剂、杀软体动物剂和杀螨剂。首选的渗透增强化合物是 1-n-dodecylaza cycloheptan-2-酮。
• pH-indicating material and cat litter containing same
  申请人：ANITOX CORPORATION

  公开号：EP0569232A1

  公开（公告）日：1993-11-10

  A pH-indicating material capable of undergoing a clearly visually detectable color transition at a desired pH, e.g., at a pH at or below about 5.6 and/or at a pH at or above about 7.6. When the pH-indicating material is wetted on its surface with liquid animal dross, particularly animal urine, such as cat urine, the pH-indicating material will undergo a clearly visible color transition at a urine-problematic pH, e.g., acidic or alkaline. The pH-indicating material is maintained on an inert carrier, separate from the cat litter material itself, so that the cat litter material does not chemically interfere with the urine pH-induced color transition provided by the dye(s) in the coating material, and so that the color transition is an exclusive result of the pH of the contacting animal urine, without pH interference from the litter material. In a preferred embodiment, the pH-indicating material is admixed with any cat litter material and has dual indicators that provide one color transition at a low pH and a different color transition at a high pH so that acidic or alkaline animal urine problems can be visibly detected upon contact between the animal urine and the pH-indicating material.

  一种 pH 值指示材料，能够在所需的 pH 值（例如，pH 值为 5.6 或低于 5.6 和/或 pH 值为 7.6 或高于 7.6）下发生清晰可见的颜色转变。当 pH 值指示材料的表面被液态动物粪便，特别是动物尿液（如猫尿）浸湿时，pH 值指示材料将在尿液问题的 pH 值（如酸性或碱性）下发生清晰可见的颜色转变。pH 指示材料保存在惰性载体上，与猫砂材料本身分开，这样猫砂材料就不会对涂层材料中的染料所提供的由尿液 pH 值引起的颜色转换产生化学干扰，从而使颜色转换完全由接触的动物尿液的 pH 值决定，而不受猫砂材料 pH 值的干扰。在一个优选的实施方案中，pH 值指示材料与任何猫砂材料混合，并具有双指示剂，在低 pH 值时提供一种颜色转换，在高 pH 值时提供另一种颜色转换，这样，当动物尿液与 pH 值指示材料接触时，酸性或碱性动物尿液问题就能被明显检测出来。