Isocinchomeronsaeure-2-hydrazid | 17874-77-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Isocinchomeronsaeure-2-hydrazid
• 英文别名: 6-hydrazinocarbonyl-nicotinic acid；6-Carbazoyl-nicotinsaeure；2,5-Pyridine dicarboxylic hydrazide；6-(hydrazinecarbonyl)pyridine-3-carboxylic acid
• CAS: 17874-77-0
• 化学式: C₇H₇N₃O₃
• mdl: MFCD20542925
• 分子量: 181.151
• InChiKey: HNSSZVCYAYHUIH-UHFFFAOYSA-N

物化性质

• 密度：
  1.476±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -3
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2,5-吡啶-二羧酸二甲酯 在 甲醇 、 sodium hydroxide 、 一水合肼 作用下， 反应 2.0h， 生成 Isocinchomeronsaeure-2-hydrazid
  参考文献：
  名称：

  Shinohara et al., Kobunshi Kagaku, 1958, vol. 15, p. 839,844

  摘要：

  DOI：

文献信息

• Oxidized lipid detection
  申请人：KRATOS ANALYTICAL LIMITED

  公开号：US10948502B2

  公开（公告）日：2021-03-16

  The present invention is concerned with a method of extracting oxidized lipids from a lipid solution, the method comprising (a) a derivatisation step, comprising contacting a derivatisation agent with the lipid solution such that aldehydic oxidized lipids and/or α,β-unsaturated oxidised lipids, if present in the lipid solution, are derivatised to include an anionic group, and (b) an oxidised lipid capture step, in which nanoparticles are contacted with the lipid solution, wherein the nanoparticles capture anionic-group containing oxidised lipids. The invention also includes a method of extracting aldehydic oxidized phospholipids from a lipid solution, the method comprising (a) a derivatisation step, comprising introduction of a anionic group to aldehydic oxidized lipids and/or α,β-unsaturated oxidised lipids in the lipid solution, and (b) an oxidised lipid capture step, in which nanoparticles are contacted with the lipid solution, wherein the nanoparticles bind anionic-group containing oxidised lipids.

  本发明涉及一种从脂质溶液中提取氧化脂质的方法，该方法包括(a)衍生化步骤，包括将衍生化剂与脂质溶液接触，使脂质溶液中存在的醛氧化脂质和/或α、(b) 氧化脂质捕获步骤，其中纳米颗粒与脂质溶液接触，纳米颗粒捕获含有阴离子基团的氧化脂质。本发明还包括一种从脂溶液中提取醛氧化磷脂的方法，该方法包括：(a) 衍生化步骤，包括向脂溶液中的醛氧化脂和（或）α，β-不饱和氧化脂中引入阴离子基团；(b) 氧化脂捕获步骤，其中纳米颗粒与脂溶液接触，纳米颗粒结合含有阴离子基团的氧化脂。
• CUT RESISTANT PROTECTIVE GLOVE
  申请人：AlliedSignal Inc.

  公开号：EP0510093A1

  公开（公告）日：1992-10-28
• OXIDIZED LIPID DETECTION
  申请人：Kratos Analytical Limited

  公开号：EP3105597B1

  公开（公告）日：2020-11-18
• [EN] CUT RESISTANT PROTECTIVE GLOVE
  申请人：ALLIED-SIGNAL INC.

  公开号：WO1991010409A1

  公开（公告）日：1991-07-25

  (EN) A flexible, uncoated glove made from nonmetallic fabric comprising at least one fiber is disclosed. The glove is characterized by either weighing no more than about 30 g or having a thickness of no more than about 1.25 mm (0.05 inch), being cut resistant over some portion thereof by enduring without cutting through at least 5 cycles of an impact cam cut test, having compliance so that the wearer has a high degree of tactility, and having a cut resistance of at least 5 cycles of an impact cam cut test after a disinfectant treatment with sodium hypochlorite. The gloves are particularly useful in the medical field where they provide excellent cut protection and can be disinfected at least once while maintaining an acceptable level of cut resistance. In an alternate embodiment, a similarly characterized glove is made from a layer of fibrous material adhered to a surface of an elastomeric glove without being fully encapsulated thereby. This glove is also particularly useful in the medical field where it provides excellent cut protection.(FR) L'invention se rapporte à un gant flexible sans revêtement fabriqé à partir d'un tissu non métallique contenant au moins une fibre. Ce gant se caractérise soit par un poids ne dépassant pas 30 g environ ou par une épaisseur ne dépassant pas 1,25 mm environ (0,05 pouce), par sa résistance aux coupures sur une partie du gant se traduisant par son endurance aux coupures pendant au moins 5 cycles d'un essai à la coupure par came de choc, par son élasticité de conformation qui confère à l'utilisateur un sens tactile de degré élevé, et par une résistance aux coupures d'au moins 5 cycles d'un essai à la coupure par came de choc après un traitement désinfectant à l'hypochlorite de sodium. De tels gants sont particulièrement utiles dans le domaine médical où ils assurent une excellente protection contre les coupures et peuvent être désinfectés au moins une fois tout en conservant un niveau acceptable de résistance aux coupures. Dans une variante, un gant aux caractéristiques similaires est fabriqué à partir d'une couche de matériau fibreux collée à une surface d'un gant élastomère sans être totalement enfermée par lui. Un tel gant est également particulièrement utile dans le domaine médical où il assure une excellente protection contre les coupures.
• [EN] OXIDIZED LIPID DETECTION<br/>[FR] DÉTECTION DE LIPIDES OXYDÉS
  申请人：KRATOS ANALYTICAL LTD

  公开号：WO2015121627A1

  公开（公告）日：2015-08-20

  The present invention is concerned with a method of extracting oxidized lipids from a lipid solution, the method comprising (a) a derivatisation step, comprising contacting a derivatisation agent with the lipid solution such that aldehydic oxidized lipids and/or α,β-unsaturated oxidised lipids, if present in the lipid solution, are derivatised to include an anionic group, and (b) an oxidised lipid capture step, in which nanoparticles are contacted with the lipid solution, wherein the nanoparticles capture anionic-group containing oxidised lipids. The invention also includes a method of extracting aldehydic oxidized phospholipids from a lipid solution, the method comprising (a) a derivatisation step, comprising introduction of a anionic group to aldehydic oxidized lipids and/or α,β-unsaturated oxidised lipids in the lipid solution, and (b) an oxidised lipid capture step, in which nanoparticles are contacted with the lipid solution, wherein the nanoparticles bind anionic-group containing oxidised lipids.