4-(4-methylpentyl) bromobenzene | 135883-28-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(4-methylpentyl) bromobenzene
• 英文别名: 4-(4-Methylpentyl)bromobenzene；1-bromo-4-(4-methylpentyl)benzene
• CAS: 135883-28-2
• 化学式: C₁₂H₁₇Br
• 分子量: 241.171
• InChiKey: OHJJKYFGXQIJLP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  4-(4-methylpentyl) bromobenzene 在 钯 氢氧化钾 、 copper(l) iodide 、 三乙胺 作用下， 以 甲苯 为溶剂， 生成 4-(4-methylpentyl)-phenylethyne
  参考文献：
  名称：

  Room-Temperature Discotic Nematic Liquid Crystals

  摘要：

  The use of discotic nematic liquid crystals instead of calamitic nematic liquid crystals to improve the viewing angle of a liquid crystal display device has recently been reported. Compared to the large number of calamitic molecules showing nematic phase at room temperature, the number of disk-shaped molecules showing subambient discotic nematic phase N-D are rare. In this paper we present the design, synthesis, mesomorphic behaviour and structure-property relationship of discotic nematic liquid crystals based on benzene multiyne core.

  DOI：

  10.1080/15421400390213573
• 作为产物：
  描述：

  异己酰氯 在 氢氧化钾 、 三氯化铝 、 肼 作用下， 生成 4-(4-methylpentyl) bromobenzene
  参考文献：
  名称：

  Room-Temperature Discotic Nematic Liquid Crystals

  摘要：

  The use of discotic nematic liquid crystals instead of calamitic nematic liquid crystals to improve the viewing angle of a liquid crystal display device has recently been reported. Compared to the large number of calamitic molecules showing nematic phase at room temperature, the number of disk-shaped molecules showing subambient discotic nematic phase N-D are rare. In this paper we present the design, synthesis, mesomorphic behaviour and structure-property relationship of discotic nematic liquid crystals based on benzene multiyne core.

  DOI：

  10.1080/15421400390213573
• 作为试剂：
  描述：

  4'-bromoisocaprophenone 、 氢氧化钾 、 肼 在 4-(4-methylpentyl) bromobenzene 作用下， 以to yield 4-(4-methylpentyl) bromobenzene (Compound 32)的产率得到4-(4-methylpentyl) bromobenzene
  参考文献：
  名称：

  Acetylenes disubstituted with a heteroaromatic group and a substituted

  摘要：

  化合物的公式为##STR1##，其中R.sub.1-R.sub.3独立地为氢、低碳烷基、环烷基或低烯基，A和B独立地为氢、低碳烷基、环烷基、低烯基、SR.sub.4或OR.sub.4，其中R.sub.4为低碳烷基、环烷基或低烯基；Y选自吡嗪基、嘧啶基、吡嗪基或噁唑基的群；E为低烯基、低炔基、低环烷基、低支链烷基，或由式(CH.sub.2).sub.n表示，其中n为0-5，而Z为H、OH、OR.sub.5、OCOR.sub.5、--COOH或其药学上可接受的盐、酯或酰胺、--CH.sub.2 OH、CH.sub.2 OR.sub.6、CH.sub.2 OCOR.sub.6或--CHO、CH(OR.sub.7).sub.2、CHOR.sub.8 O或COR.sub.9、CR.sub.9 (OR.sub.7).sub.2、CR.sub.9 OR.sub.8 O，其中R.sub.5为低碳烷基、苯基或低碳烷基苯基，R.sub.6为低碳烷基、苯基或低碳烷基苯基，R.sub.7为低碳烷基，R.sub.8为2-5碳的二价烷基基团，R.sub.9为含有1-5碳的烷基、环烷基或烯基基团。

  公开号：

  US05516904A1

文献信息

• USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS
  申请人：North Carolina State University

  公开号：US20130172187A1

  公开（公告）日：2013-07-04

  Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an aryl carbamate as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an aryl carbamate compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or a plant defense activator.

  本公开提供了一种防止、去除或抑制植物或其部分中微生物生物膜形成或微生物感染的方法，包括向其施加本文所述的芳基氨基甲酸酯或其农业可接受的盐的治疗有效量。还提供了增强微生物杀灭剂（例如，包括铜、抗生素、噬菌体等）和/或植物防御激活剂的方法，包括施加本文所述的活性化合物。还提供了包含本文所述的芳基氨基甲酸酯化合物的组合物，其在农业上可接受的载体中，并且在某些实施例中，这些组合物进一步包括微生物杀灭剂（例如，包括铜、抗生素、噬菌体等）和/或植物防御激活剂。
• Alkyl, alkoxy and thioalkoxy substituted diphenyl acetylenes having
  申请人：Allergan, Inc.

  公开号：US05202471A1

  公开（公告）日：1993-04-13

  Retinoid like activity is exhibited by compounds of the formula ##STR1## where R.sub.1 -R.sub.4 independently are hydrogen, lower alkyl, cycloalkyl or lower alkenyl, A and B independently are hydrogen, lower alkyl cycloalkyl, lower alkenyl, SR* or OR* where R* is lower alkyl, cycloalkyl or lower alkenyl; Y is lower alkenyl, lower alkynyl, lower cycloalkyl, lower branched chain alkyl or (CH.sub.2).sub.n where n is 0-6; and Z is H, --COOH or a pharmaceutically acceptable salt, ester or amide thereof, --CH.sub.2 OH or an ether or ester derivative, or --CHO or an acetal derivative, or --COR' or a ketal derivative where R' is an alkyl, cycloalkyl or alkenyl group containing 1 to 5 carbons.

  化合物的结构式为##STR1##，其中R.sub.1 -R.sub.4独立地是氢、较低的烷基、环烷基或较低的烯基，A和B独立地是氢、较低的烷基、环烷基、较低的烯基、SR*或OR*，其中R*是较低的烷基、环烷基或较低的烯基；Y是较低的烯基、较低的炔基、较低的环烷基、较低的支链烷基或(CH.sub.2).sub.n，其中n为0-6；Z是H、--COOH或其药用可接受的盐、酯或酰胺，--CH.sub.2 OH或醚或酯衍生物，或--CHO或缩醛衍生物，或--COR'或缩酮衍生物，其中R'是含有1至5个碳的烷基、环烷基或烯基基团。
• Acetylenes disubstituted with a pyridinyl group and a substituted phenyl
  申请人：Allergan, Inc.

  公开号：US05013744A1

  公开（公告）日：1991-05-07

  Retinold like activity is exhibited by compounds of the formula ##STR1## where R.sub.1 -R.sub.3 independently are hydrogen, lower alkyl, cycloalkyl or lower alkenyl, A and B independently are hydrogen, lower alkyl, cycloalkyl, lower alkenyl, SR.sub.4 or OR.sub.4 where R.sub.4 is lower alkyl, cycloalkyl or lower alkenyl; Y is pyridyl; E is lower alkenyl, lower alkynyl, lower cycloalkyl, lower branched chain alkyl, or is characterized by the formula (CH.sub.2).sub.n where n is 0-5, and Z is H, OH, OR.sub.5, OCOR.sub.5, --COOH or a pharmaceutically acceptable salt, ester or amide thereof, --CH.sub.2 OH, CH.sub.2 OR.sub.6, CH.sub.2 OCOR.sub.6, or --CHO, CH(OR.sub.7).sub.2, CHOR.sub.8 O, or COR.sub.9, CR.sub.9 (OR.sub.7).sub.2, CR.sub.9 OR.sub.8 O where R.sub.5 is lower alkyl, phenyl or lower alkylphenyl, R.sub.6 is lower alkyl, phenyl or lower alkylphenyl, R.sub.7 is lower alkyl, R.sub.8 is a divalent alkyl radical of 2-5 carbons, and R.sub.9 is an alkyl, cycloalkyl or alkenyl group containing 1 to 5 carbons.

  化合物的公式为##STR1##，其中R.sub.1 -R.sub.3独立地是氢、较低的烷基、环烷基或较低的烯基，A和B独立地是氢、较低的烷基、环烷基、较低的烯基、SR.sub.4或OR.sub.4，其中R.sub.4是较低的烷基、环烷基或较低的烯基；Y是吡啶基；E是较低的烯基、较低的炔基、较低的环烷基、较低的支链烷基，或者由公式(CH.sub.2).sub.n表示，其中n为0-5，Z是H、OH、OR.sub.5、OCOR.sub.5、--COOH或其药学上可接受的盐、酯或酰胺，--CH.sub.2 OH、CH.sub.2 OR.sub.6、CH.sub.2 OCOR.sub.6，或--CHO、CH(OR.sub.7).sub.2、CHOR.sub.8 O，或COR.sub.9，CR.sub.9 (OR.sub.7).sub.2，CR.sub.9 OR.sub.8 O，其中R.sub.5是较低的烷基、苯基或较低的烷基苯基，R.sub.6是较低的烷基、苯基或较低的烷基苯基，R.sub.7是较低的烷基，R.sub.8是含有2-5个碳的二价烷基基团，R.sub.9是含有1到5个碳的烷基、环烷基或烯基基团。
• Acetylenes disubstituted with a thiazole group and a substituted phenyl
  申请人：Allergan, Inc.

  公开号：US05414007A1

  公开（公告）日：1995-05-09

  Retinoid like activity is exhibited by compounds of the formula ##STR1## where R.sub.1 -R.sub.3 independently are hydrogen, lower alkyl, cycloalkyl or lower alkenyl, A and B independently are hydrogen, lower alkyl, cycloalkyl, lower alkenyl, SR.sub.4 or OR.sub.4 where R.sub.4 is lower alkyl, cycloalkyl or lower alkenyl; Y is selected from a group consisting of pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl or oxazolyl; E is lower alkenyl, lower alkynyl, lower cycloalkyl, lower branched chain alkyl, or is characterized by the formula (CH.sub.2).sub.n where n is 0-5, and Z is H, OH, OR.sub.5, OCOR.sub.5, --COOH or a pharmaceutically acceptable salt, ester or amide thereof, --CH.sub.2 OH, CH.sub.2 OR.sub.6, CH.sub.2 OCOR.sub.6, or --CHO, CH(OR.sub.7).sub.2, CHOR.sub.8 O, or COR.sub.9, CR.sub.9 (OR.sub.7).sub.2, CR.sub.9 OR.sub.8 O where R.sub.5 is lower alkyl, phenyl or lower alkylphenyl, R.sub.6 is lower alkyl, phenyl or lower alkylphenyl, R.sub.7 is lower alkyl, R.sub.8 is a divalent alkyl radical of 2-5 carbons, and R.sub.9 is an alkyl, cycloalkyl or alkenyl group containing 1 to 5 carbons.

  化合物的结构式为##STR1##，其中R.sub.1-R.sub.3独立地为氢、低碳基、环烷基或低烯基，A和B独立地为氢、低碳基、环烷基、低烯基、SR.sub.4或OR.sub.4，其中R.sub.4为低碳基、环烷基或低烯基；Y选自吡啶啉基、嘧啶啉基、吡嗪基、噻唑基或噁唑基的群；E为低烯基、低炔基、低环烷基、低支链烷基，或由式(CH.sub.2).sub.n表示，其中n为0-5，Z为H、OH、OR.sub.5、OCOR.sub.5、--COOH或其药学上可接受的盐、酯或酰胺，--CH.sub.2 OH、CH.sub.2 OR.sub.6、CH.sub.2 OCOR.sub.6或--CHO，CH(OR.sub.7).sub.2、CHOR.sub.8 O或COR.sub.9，CR.sub.9(OR.sub.7).sub.2、CR.sub.9OR.sub.8 O，其中R.sub.5为低碳基、苯基或低碳基苯基，R.sub.6为低碳基、苯基或低碳基苯基，R.sub.7为低碳基，R.sub.8为2-5碳原子的二价烷基基团，R.sub.9为含有1至5个碳原子的烷基、环烷基或烯基基团。
• Acetylenes disubstituted with a furyl group and a substituted phenyl
  申请人：Allergan, Inc.

  公开号：US05264456A1

  公开（公告）日：1993-11-23

  Retinoid like activity is exhibited by compounds of the formula ##STR1## where R.sub.1 -R.sub.3 independently are hydrogen, lower alkyl, cycloalkyl or lower alkenyl, A and B independently are hydrogen, lower alkyl, cycloalkyl, lower alkenyl, SR.sub.4 or OR.sub.4 where R.sub.4 is lower alkyl, cycloalkyl or lower alkenyl; Y is selected from a group consisting of furyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl or oxazolyl; E is lower alkenyl, lower alkynyl, lower cycloalkyl, lower branched chain alkyl, or is characterized by the formula (CH.sub.2).sub.n where n is 0-5, and Z is H, OH, OR.sub.5, OCOR.sub.5, --COOH or a pharmaceutically acceptable salt, ester or amide thereof, --CH.sub.2 OH, CH.sub.2 OR.sub.6, CH.sub.2 OCOR.sub.6, or --CHO, CH(OR.sub.7).sub.2, CHOR.sub.8 O, or COR.sub.9, CR.sub.9 (OR.sub.7).sub.2, CR.sub.9 OR.sub.8 O where R.sub.5 is lower alkyl, phenyl or lower alkylphenyl, R.sub.6 is lower alkyl, phenyl or lower alkylphenyl, R.sub.7 is lower alkyl, R.sub.8 is a divalent alkyl radical of 2-5 carbons, and R.sub.9 is an alkyl, cycloalkyl or alkenyl group containing 1 to 5 carbons.

  化合物的公式为##STR1##，其中R.sub.1-R.sub.3独立地为氢，较低的烷基，环烷基或较低的烯基，A和B独立地为氢，较低的烷基，环烷基，较低的烯基，SR.sub.4或OR.sub.4，其中R.sub.4为较低的烷基，环烷基或较低的烯基；Y从由呋喃基，吡嗪基，嘧啶基，吡嗪啉基，噻唑基或噁唑基组成的群体中选择；E为较低的烯基，较低的炔基，较低的环烷基，较低的支链烷基，或由公式(CH.sub.2).sub.n表示，其中n为0-5，Z为H，OH，OR.sub.5，OCOR.sub.5，--COOH或其药学上可接受的盐，酯或酰胺，--CH.sub.2 OH，CH.sub.2 OR.sub.6，CH.sub.2 OCOR.sub.6，或--CHO，CH(OR.sub.7).sub.2，CHOR.sub.8 O，或COR.sub.9，CR.sub.9(OR.sub.7).sub.2，CR.sub.9OR.sub.8O，其中R.sub.5为较低的烷基，苯基或较低的烷基苯基，R.sub.6为较低的烷基，苯基或较低的烷基苯基，R.sub.7为较低的烷基，R.sub.8为2-5个碳的双价烷基基团，R.sub.9为含有1-5个碳的烷基，环烷基或烯基。