1,1-dimethyl-4-(2,3,4,5-tetrafluorobenzoyl)piperazine | 1455134-80-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1-dimethyl-4-(2,3,4,5-tetrafluorobenzoyl)piperazine
• 英文别名: (4-Methylpiperazin-1-yl)-(2,3,4,5-tetrafluorophenyl)methanone
• CAS: 1455134-80-1
• 化学式: C₁₂H₁₂F₄N₂O
• 分子量: 276.234
• InChiKey: YBLABXKBINUKHN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  23.6
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  1,1-dimethyl-4-(2,3,4,5-tetrafluorobenzoyl)piperazine 、 碘甲烷 以 二氯甲烷 为溶剂， 以96%的产率得到1,1-dimethyl-4-(2,3,4,5-tetrafluorobenzoyl)piperazinium iodide
  参考文献：
  名称：

  Inhibitory activity of fluorine-containing quaternary ammonium salts comprising an N-methylpiperazinyl moiety

  摘要：

  New fluorine-containing quaternary ammonium salts comprising an N-methylpiperazinyl moiety, which exhibited a high inhibiting capacity against hydrochloric acid corrosion of low-carbon steel, were synthesized. The polarization-resistance method was applied to determine the uniform corrosion rate of steel-3 in relation to the structure and concentration of the fluorine-containing substituents in the salts. It was found that the structure of the fluorine-containing moiety of the quaternary ammonium salts does not significantly influence the corrosion processes.

  DOI：

  10.1134/s1070427213070082
• 作为产物：
  描述：

  N-甲基哌嗪 、 四氟苯甲酰氯 以 二氯甲烷 为溶剂， 反应 2.0h， 以75%的产率得到1,1-dimethyl-4-(2,3,4,5-tetrafluorobenzoyl)piperazine
  参考文献：
  名称：

  Inhibitory activity of fluorine-containing quaternary ammonium salts comprising an N-methylpiperazinyl moiety

  摘要：

  New fluorine-containing quaternary ammonium salts comprising an N-methylpiperazinyl moiety, which exhibited a high inhibiting capacity against hydrochloric acid corrosion of low-carbon steel, were synthesized. The polarization-resistance method was applied to determine the uniform corrosion rate of steel-3 in relation to the structure and concentration of the fluorine-containing substituents in the salts. It was found that the structure of the fluorine-containing moiety of the quaternary ammonium salts does not significantly influence the corrosion processes.

  DOI：

  10.1134/s1070427213070082

文献信息

• Inhibitory activity of fluorine-containing quaternary ammonium salts comprising an N-methylpiperazinyl moiety
  作者：T. I. Gorbunova、D. N. Bazhin、A. Ya. Zapevalov、V. I. Saloutin

  DOI：10.1134/s1070427213070082

  日期：2013.7

  New fluorine-containing quaternary ammonium salts comprising an N-methylpiperazinyl moiety, which exhibited a high inhibiting capacity against hydrochloric acid corrosion of low-carbon steel, were synthesized. The polarization-resistance method was applied to determine the uniform corrosion rate of steel-3 in relation to the structure and concentration of the fluorine-containing substituents in the salts. It was found that the structure of the fluorine-containing moiety of the quaternary ammonium salts does not significantly influence the corrosion processes.