Benzenesulfinylmethanol | 1313537-36-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzenesulfinylmethanol
• CAS: 1313537-36-8
• 化学式: C₇H₈O₂S
• 分子量: 156.205
• InChiKey: NKXARXOLGHRNAW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  56.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  hydroxymethyl phenyl sulfide 在 叔丁基过氧化氢 、 二氧化硫脲 作用下， 以 十二烷 、 二氯甲烷 为溶剂， 反应 5.5h， 以80%的产率得到Benzenesulfinylmethanol
  参考文献：
  名称：

  Thiourea dioxide (TUD): a robust organocatalyst for oxidation of sulfides to sulfoxides with TBHP under mild reaction conditions

  摘要：

  Thiourea dioxide (TUD) has been reported for the first time as a highly efficient and selective organocatalyst for the oxidation of sulfides to sulfoxides in high to excellent yields by using tert-butylhydroperoxide as oxidant under mild reaction conditions. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.04.088

文献信息

• A New Hepta-Nuclear Ti-Oxo-Cluster-Substituted Tungstoantimonate and Its Catalytic Oxidation of Thioethers
  作者：Hai-Lou Li、Chen Lian、Da-Peng Yin、Zhi-Yu Jia、Guo-Yu Yang

  DOI：10.1021/acs.cgd.8b01474

  日期：2019.1.2

  A neoteric hepta-nuclear Ti-oxo-cluster-substituted tetrameric tungstoantimonate [H2N(CH3)2]22Na18Ti7O6(SbW9O33)4}2·124H2O (1) has hydrothermally been synthesized and tested by single-crystal/powder X-ray diffraction, IR spectra, and thermal analysis. The glamorous feature of this tetrameric polyoxoanion is an uncommon hepta-nuclear Ti-oxo-cluster octahedron [Ti7O6]16+ enclosed in four [B-α-SbW9O33]9– building units. As a heterogeneous catalyst, the investigation on catalytic oxidation with H2O2 for multiple thioethers indicated that 1 possesses high conversion and remarkable selectivity. Additionally, 1 exhibits good stability and excellent recyclability.

  通过水热法合成了一种新七核钛氧簇取代的四元钨锑酸盐[H2N(CH3)2]22Na18Ti7O6(SbW9O33)4}2-124H2O (1)，并通过单晶/粉末 X 射线衍射、红外光谱和热分析进行了测试。这种四元多氧阴离子的迷人之处在于，在四个[B-α-SbW9O33]9-构筑单元中包含了一个不常见的七核钛氧簇八面体[Ti7O6]16+。作为一种异相催化剂，用 H2O2 对多种硫醚进行催化氧化的研究表明，1 具有高转化率和显著的选择性。此外，1 还具有良好的稳定性和出色的可回收性。
• [EN] IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS<br/>[FR] DERIVES D'IMIDAZOPYRIDINE EN TANT QU'INHIBITEURS DE KINASE
  申请人：GLAXO GROUP LTD

  公开号：WO2003080610A1

  公开（公告）日：2003-10-02

  A compound of the formula: (I) and-physiologically acceptable salts and or N-oxides thereof wherein, X1 is N or CR.3; X2 is N or CR'4; X3 ,is..N or CR5; X4 is N or CR6 with the proviso that at least one but not more than two of X1, X 2, X,3. and X4 represents N. R1 is a 5-, or 6-membered heterocyclic group selected from group a, b, c or d formula: (II) wherein X5 is a group selected from N or CR7: and X6, is a group selected from O, S or NR8; X7 and X8; which maybe the same or, different is a group selected from N or CR9; ; X9, is a group selected from O, S or NR8 and X10 is N or CR10 ; X11 , X12 and X13 may be the same or different and selected from a group N or CR11 ; processes for their preparation, pharmaceutical compositions containing them and their use in medicine.

  化合物的式子为：（I），其生理上可接受的盐和/或N-氧化物，其中，X1为N或CR.3；X2为N或CR'4；X3为N或CR5；X4为N或CR6，但至少其中一个但不超过两个X1、X2、X3和X4代表N。R1是从a、b、c或d组中选择的5-或6-成员杂环基，式子为：（II），其中X5是从N或CR7选择的基团；X6是从O、S或NR8选择的基团；X7和X8可以相同或不同，是从N或CR9选择的基团；X9是从O、S或NR8选择的基团，X10是N或CR10；X11、X12和X13可以相同或不同，是从N或CR11的基团中选择的；制备它们的过程，包含它们的制药组合物以及它们在医学上的用途。
• Imidazopyridine derivatives as kinase inhibitors
  申请人：Bailey Nicholas

  公开号：US20050197328A1

  公开（公告）日：2005-09-08

  A compound of the formula and physiologically acceptable salts and or N-oxides thereof wherein, X 1 is N or CR 3 ; X 2 is N or CR 4 ; X 3 is N or CR 5 ; X 4 is N or CR 6 . with the proviso that at least one but not more than two of X 1 , X 2 , X 3 and X 4 represents N. R 1 is a 5-, or 6-membered heterocyclic group selected from group a, b, c or d wherein X 5 is a group selected from N or CR 7 and X 6 is a group selected from O, S or NR 8; X 7 and X 8 which may be the same or different is a group selected from N or CR 9; X 9 is a group selected from O, S or NR 8 and X 10 is N or CR 10; X 11 , X 12 and X 13 may be the same or different and selected from a group N or CR 11 ; processes for their preparation, pharmaceutical compositions containing them and their use in medicine.

  式中化合物及其生理上可接受的盐和/或N-氧化物，其中： X1为N或CR3； X2为N或CR4； X3为N或CR5； X4为N或CR6； 但须满足X1、X2、X3和X4中至少一个但不超过两个为N； R1为从a、b、c或d组中选择的5-或6-成员杂环基，其中X5为N或CR7组，X6为O、S或NR8组； X7和X8可以相同或不同，为N或CR9组； X9为O、S或NR8组，X10为N或CR10组； X11、X12和X13可以相同或不同，为N或CR11组； 本发明还涉及其制备方法、包含它们的制药组合物以及它们在医学上的应用。
• Tetrazoyloxime derivative and plant disease control agent
  申请人：NIPPON SODA CO., LTD.

  公开号：EP2669282A1

  公开（公告）日：2013-12-04

  According to the present invention, a tetrazoyloxime derivative and a salt thereof, which are excellent in a control effect against plant disease injury, and a plant disease controlling agent containing the same as an active ingredient are provided. The tetrazoyloxime derivative has a structure represented by formula (1) shown below:

  根据本发明，提供了一种对植物病害伤害具有优异防治效果的四唑酰肟衍生物及其盐，以及一种以其为有效成分的植物病害防治剂。四唑肟衍生物的结构如下式（1）所示：
• TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT
  申请人：Nippon Soda Co., Ltd.

  公开号：EP2177519B1

  公开（公告）日：2015-05-27