2-ethyl-5-pentyl-5-pyrroline | 61772-95-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 英文名称: 2-ethyl-5-pentyl-5-pyrroline
• 英文别名: 5-Ethyl-2-pentyl-1-pyrrolin；5-ethyl-2-pentyl-1-pyrroline；2-Aethyl-5-pentyl-5-pyrrolin；2-Ethyl-5-pentyl-5-pyrrolin；2-ethyl-5-pentyl-3,4-dihydro-2H-pyrrole；2-Ethyl-5-pentyl-3,4-dihydro-2H-pyrrole
• CAS: 61772-95-0
• 化学式: C₁₁H₂₁N
• 分子量: 167.294
• InChiKey: VXXHEVJFTBKPKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (E,3E)-3-(dimethylhydrazinylidene)undec-4-en-6-one 以32%的产率得到
  参考文献：
  名称：

  MAYRING, L.;SEVERIN, T., CHEM. BER., 1981, 114, N 12, 3863-3877

  摘要：

  DOI：

文献信息

• Unsymmetrical 2,5-dialkylpyrrolidines via reductive amination of 1,4-diketones
  作者：Tappey H. Jones、James B. Franko、Murray S. Blum、H.M. Fales

  DOI：10.1016/s0040-4039(00)71506-1

  日期：1980.1

  Reductive amination of 1,4-diketones with sodium cyanoborohydride and ammonium acetate produced 2,5-dialkylpyrrolidines in good yield and permitted inclusion of side chain unsaturation. The compounds were found in ants of the genus Monomorium.

  用氰基硼氢化钠和乙酸铵对1，4-二酮进行还原胺化反应可得到高产率的2，5-二烷基吡咯烷，并允许包含侧链不饱和键。这些化合物发现于Monomorium属的蚂蚁中。
• Palladium-catalyzed intramolecular addition of amines to acetylenes. Synthesis of cyclic imines
  作者：Yukitoshi Fukuda、Seijiro Matsubara、Kiitiro Utimoto

  DOI：10.1021/jo00020a023

  日期：1991.9

  Intramolecular aminopalladation of alkynylamines gave intermediary alkenylpalladium compounds that hydrolyzed and isomerized to thermodynamically stable cyclic imines. Treatment of 3-alkynylamines with a catalytic amount of PdCl2(MeCN)2 gave exclusively 1-pyrrolines in good yields; 5-alkynylamines afforded 2,3,4,5-tetrahydropyridines selectively. Treatment of 4-alkynylamines with Pd(II) afforded mixtures of both 5- and 6-membered cyclic imines. Applications to the synthesis of some naturally occurring alkaloids are also described.
• Mayring, Lothar; Severin, Theodor, Chemische Berichte, 1981, vol. 114, p. 3863 - 3877
  作者：Mayring, Lothar、Severin, Theodor

  DOI：——

  日期：——