diphosphatidylglycerol | 72577-51-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: diphosphatidylglycerol
• 英文别名: 1,3-di(1,2-dipalmitoyl-sn-glycero-3-phospho)glycerol；[3-[[3-[2,3-Di(hexadecanoyloxy)propoxy-hydroxyphosphoryl]oxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxy-2-hexadecanoyloxypropyl] hexadecanoate
• CAS: 72577-51-6
• 化学式: C₇₃H₁₄₂O₁₇P₂
• 分子量: 1353.87
• InChiKey: GRTNLBQYBYZCCM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  26.1
• 重原子数：
  92
• 可旋转键数：
  78
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  237
• 氢给体数：
  3
• 氢受体数：
  17

反应信息

• 作为产物：
  描述：

  二十六烷酰磷脂酸 在 钯 吡啶 、 2,4,6-三异丙基苯磺酰氯 、 氢气 作用下， 以 正己烷 为溶剂， 反应 72.0h， 生成 diphosphatidylglycerol
  参考文献：
  名称：

  Stepanov, A. E.; Makarova, I. M.; Shvets, V. I., Journal of Organic Chemistry USSR (English Translation), 1984, p. 896 - 899

  摘要：

  DOI：

文献信息

• Compositions and methods for cancer immunotherapy
  申请人：Rossignol P. Daniel

  公开号：US20070020232A1

  公开（公告）日：2007-01-25

  The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment for cancer, or in post-therapy recovery from cancer or the compounds of the invention can be administered as a prophylactic to a subject individual to prevent or delay the development of cancer.
• Immunomodulatory compounds and methods of use thereof
  申请人：Hawkins D. Lynn

  公开号：US20070027111A1

  公开（公告）日：2007-02-01

  The present invention is directed to methods of treating diseases and disorders related to immune responses by administering one or more immunomodulatory compounds. In particular, the invention is directed to methods of stimulating and reducing immune responses, therapeutic and prophylactic treatment of cancer, treating autoimmune conditions, treating allergic reactions and asthma, and preventing ischemic damage and asthma by administering one or more immunomodulatory compounds.
• Compositions and methods for immunotherapy
  申请人：Fields Z. Scott

  公开号：US20070292418A1

  公开（公告）日：2007-12-20

  The invention relates to immunotherapeutic compounds, compositions that include such compounds, and methods of using the compounds, for example, to treat an individual having, at risk for, or previously treated for a cancer.
• Compositions and Methods for Immunotherapy
  申请人：Fields Scott Z.

  公开号：US20110243935A1

  公开（公告）日：2011-10-06

  The invention relates to immunotherapeutic compounds, compositions that include such compounds, and methods of using the compounds, for example, to treat an individual having, at risk for, or previously treated for a cancer.
• Compositions and Methods for Cancer Immunotherapy
  申请人：Rossignol Daniel P.

  公开号：US20110250171A1

  公开（公告）日：2011-10-13

  The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment for cancer, or in post-therapy recovery from cancer or the compounds of the invention can be administered as a prophylactic to a subject individual to prevent or delay the development of cancer.