4-(2-Hydroxy-ethyl)-7-oxa-bicyclo[2.2.1]heptan-1-ol | 93675-86-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢呋喃
• 英文名称: 4-(2-Hydroxy-ethyl)-7-oxa-bicyclo[2.2.1]heptan-1-ol
• 英文别名: Rengyoxide；4-(2-hydroxyethyl)-7-oxabicyclo[2.2.1]heptan-1-ol
• CAS: 93675-86-6
• 化学式: C₈H₁₄O₃
• 分子量: 158.197
• InChiKey: ZJAVMYIMENEGJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-(8-羟基-1,4-二氧杂螺[4.5]癸烷-8-基)乙酸乙酯 在 Dowex 50X₈-100 (H⁺ form) 、 水 作用下， 以 乙醚 为溶剂， 反应 26.8h， 生成 4-(2-Hydroxy-ethyl)-7-oxa-bicyclo[2.2.1]heptan-1-ol
  参考文献：
  名称：

  Chemoenzymatic synthesis of rengyoside -A, -B, isorengyoside and synthesis of their aglycones

  摘要：

  The chemoenzymatic synthesis of a group of naturally occurring cyclohexylethanoids, rengyoside-A, -B and isorengyoside, has been performed by enzymatic glucosidation of their chemically synthesized aglycones, rengyol, rengyoxide and isorengyol. (C) 1997 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00138-5

文献信息

• ENDO, KATSUYA;SEYA, KAZUHIKO;HIKINO, HIROSHI, TETRAHEDRON, 45,(1989) N2, C. 3673-3682
  作者：ENDO, KATSUYA、SEYA, KAZUHIKO、HIKINO, HIROSHI

  DOI：——

  日期：——
• Chemoenzymatic synthesis of rengyoside -A, -B, isorengyoside and synthesis of their aglycones
  作者：Annunziata Soriente、Anna Della Rocca、Guido Sodano、Antonio Trincone

  DOI：10.1016/s0040-4020(97)00138-5

  日期：1997.3

  The chemoenzymatic synthesis of a group of naturally occurring cyclohexylethanoids, rengyoside-A, -B and isorengyoside, has been performed by enzymatic glucosidation of their chemically synthesized aglycones, rengyol, rengyoxide and isorengyol. (C) 1997 Published by Elsevier Science Ltd.