2-(5-Phenyl-1,3,4-thiadiazol-2-yl)-benzoesaeure | 59415-41-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(5-Phenyl-1,3,4-thiadiazol-2-yl)-benzoesaeure
• 英文别名: 2-(5-Phenyl-1,3,4-thiadiazol-2-yl)benzoic acid
• CAS: 59415-41-7
• 化学式: C₁₅H₁₀N₂O₂S
• 分子量: 282.323
• InChiKey: JNWFJOCRUUQDND-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91.3
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  N-benzoyl-N'-2-methylbenzoylhydrazide 在 sodium dichromate 、 tetraphosphorus decasulfide 、 硫酸 作用下， 以 吡啶 、 溶剂黄146 为溶剂， 反应 2.0h， 生成 2-(5-Phenyl-1,3,4-thiadiazol-2-yl)-benzoesaeure
  参考文献：
  名称：

  Synthetic plant growth regulators. The synthesis of C-o-Carboxyphenyl derivatives of some five-membered heterocycles

  摘要：

  某些杂环化合物所需的 研究了某些杂环化合物的邻羧基苯基衍生物的合成路线。 作为植物生长调节剂进行测试。制备 2-(5-苯基-1,3,4-恶二唑-2-基)苯甲酸 (3)、 2-(5-苯基-1,3,4-噻二唑-2-基)苯甲酸 (4)、 2-(5-苯基-1H-1,2,4-三唑-3-基)苯甲酸（5 1,2,4-恶二唑-5-基）苯甲酸 (6)、2-（2-苯基噻唑-4-基）苯甲酸 (7), 2-(3-苯基异恶唑-5-基)苯甲酸 (8), 2-(5-苯基异恶唑-3-基)苯甲酸 (9) 酸 (9) 以及 (3)、(4)、(8) 和 (9) 的氯衍生物。

  DOI：

  10.1071/ch9772225

文献信息

• Plant growth regulants
  申请人：Uniroyal, Inc.

  公开号：US03947263A1

  公开（公告）日：1976-03-30

  Plant growth regulant effects, such as dwarfing, cessation of terminal growth, increased flower set, increased fruit and pod set, fruiting body abortion, twisting and epinastic responses, etc., may be accomplished on crops such as soybeans, cotton, etc., by application of certain 2-(1,3,4-oxadiazol-2-yl) or 2-(2-oxazolyl) or 2-(1,3,4-thiadiazol-2-yl)benzoic acids, salts and esters, having the formula ##SPC1## Where X is nitrogen or C--R" (R" being hydrogen or methyl), Z is oxygen or sulfur when X is nitrogen, Z is oxygen when X is C--R", R is phenyl or various substituents, and R' is hydrogen or various substituents. An example is 2-(5-phenyl-1,3,4-oxadiazol-2-yl)benzoic acid. The compounds where X is nitrogen and Z is sulfur are new compounds, e.g., 2-(5-phenyl-1,3,4-thiadiazol-2-yl)benzoic acid.

  植物生长调节剂的效果，如矮化、终止生长、增加花朵结实、增加果实和荚果结实、果实萎缩、扭曲和上翘反应等，可以通过应用某些2-(1,3,4-噁唑-2-基)或2-(2-噁唑基)或2-(1,3,4-噻唑-2-基)苯甲酸、盐和酯在大豆、棉花等作物上实现，其化学式为##SPC1##其中X为氮或C--R"（R"为氢或甲基），Z为氮时为氧或硫，Z为C--R"时为氧，R为苯基或各种取代基，R'为氢或各种取代基。例如2-(5-苯基-1,3,4-噁唑-2-基)苯甲酸。其中X为氮，Z为硫的化合物是新化合物，例如2-(5-苯基-1,3,4-噻唑-2-基)苯甲酸。
• Method of retarding the growth of plants using certain oxadiazolyl,
  申请人：Uniroyal Inc.

  公开号：US04035175A1

  公开（公告）日：1977-07-12

  Plant growth regulant effects, such as dwarfing, cessation of terminal growth, increased flower set, increased fruit and pod set, fruiting body abortion, twisting and epinastic responses, etc., may be accomplished on crops such as soybeans, cotton, etc., by application of certain 2-(1,3,4-oxadiazol-2-yl) or 2-(2-oxazolyl) or 2-(1,3,4-thiadiazol-2-yl)benzoic acids, salts and esters, having the formula ##STR1## where X is nitrogen or C--R" (R" being hydrogen or methyl), Z is oxygen or sulfur when X is nitrogen, Z is oxygen and when X is C--R", R is phenyl or various substituents, and R' is hydrogen or various substituents. An example is 2-(5-phenyl-1,3,4-oxadiazol-2-yl)benzoic acid. The compounds where X is nitrogen and Z is sulfur are new compounds, e.g., 2-(5-phenyl-1,3,4-thiadiazol-2-yl)benzoic acid.

  植物生长调节剂的效果，例如矮化、终止顶端生长、增加花朵结实、增加果实和荚果结实、果实堕落、扭曲和上升反应等，可以通过施用某些2-(1,3,4-噁二唑-2-基)或2-(2-噁唑基)或2-(1,3,4-噻二唑-2-基)苯甲酸、盐和酯等化合物在作物上实现，其化学式为##STR1##其中X是氮或C--R"（R"为氢或甲基），Z是氮时为氧或硫，Z是氧时为氧，当X为C--R"时，R为苯基或各种取代基，R'为氢或各种取代基。一个例子是2-(5-苯基-1,3,4-噁二唑-2-基)苯甲酸。其中X为氮，Z为硫的化合物是新的化合物，例如2-(5-苯基-1,3,4-噻二唑-2-基)苯甲酸。
• 2-(5-Phenyl-1,3,4-thiadiazol-2-yl)benzoic acid
  申请人：Uniroyal, Inc.

  公开号：US04120861A1

  公开（公告）日：1978-10-17

  Plant growth regulant effects, such as dwarfing, cessation of terminal growth, increased flower set, increased fruit and pod set, fruiting body abortion, twisting and epinastic responses, etc., may be accomplished on crops such as soybeans, cotton, etc., by application of certain 2-(1,3,4-oxadiazol-2-yl) or 2-(2-oxazolyl) or 2-(1,3,4-thiadiazol-2-yl)benzoic acids, salts and esters, having the formula ##STR1## where X is nitrogen or C-R" (R" being hydrogen or methyl), Z is oxygen or sulfur when X is nitrogen, Z is oxygen when X is C-R", R is phenyl or various substituents, and R' is hydrogen or various substituents. An example is 2-(5-phenyl-1,3,4-oxadiazol-2-yl) benzoic acid. The compounds where X is nitrogen and Z is sulfur are new compounds, e.g., 2-(5-phenyl-1,3,4-thiadiazol-2-yl)benzoic acid.

  应用某些2-(1,3,4-噁二唑-2-基)或2-(2-噁唑基)或2-(1,3,4-噻二唑-2-基)苯甲酸、盐和酯，如##STR1##可在大豆、棉花等作物上实现植物生长调节剂效应，如矮化、终止生长、增加花朵结实、增加果实和荚果结实、果实堕落、扭曲和上卷反应等。其中，X为氮或C-R"（R"为氢或甲基），Z为氮时为氧或硫，Z为C-R"时为氧，R为苯基或各种取代基，R'为氢或各种取代基。例如，2-(5-苯基-1,3,4-噁二唑-2-基)苯甲酸。其中，X为氮，Z为硫的化合物是新化合物，例如2-(5-苯基-1,3,4-噻二唑-2-基)苯甲酸。
• HARRIS R. L. N.; HUPPATZ J. L., AUSTRAL. J. CHEM. <AJCH-AS>, 1977, 30, NO 10, 2225-2240
  作者：HARRIS R. L. N.、 HUPPATZ J. L.

  DOI：——

  日期：——
• US3947263A
  申请人：——

  公开号：US3947263A

  公开（公告）日：1976-03-30