1H,1H,2H,2H-perfluorohexylethylene | 106128-18-1

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 1H,1H,2H,2H-perfluorohexylethylene
• 英文别名: 5,5,6,6,7,7,8,8,8-Nonafluoro-1-octene；5,5,6,6,7,7,8,8,8-nonafluorooct-1-ene
• CAS: 106128-18-1
• 化学式: C₈H₇F₉
• 分子量: 274.129
• InChiKey: UKHHFSFZWOJZHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  三乙基硅烷 、 全氟碘代丁烷 、 1H,1H,2H-全氟-1-己烯 以 various solvent(s) 为溶剂， 生成 1H,1H,2H,2H-perfluorohexylethylene 、 4-gem-bis(2,2,3,3,4,4,5,5,5-nonafluoropentyl)-1-butene
  参考文献：
  名称：

  Reactivity of perfluoro-n-alkyl radicals with reluctant substrates. Rates of addition to RFCH2CH=CH2 and RFCH=CH2

  摘要：

  Conditions for conducting competitive experiments involving slow reactions of perfluoroalkyl radicals have been defined. A revised value for the rate constant for hydrogen abstraction from Et3SiH is reported [(5.0 +/- 0.4) x 10(5) M(-1)s(-1)], as we the rate, constants for addition of the n-C4F9. radical to CH2=CHCH2C4F9 [1.15 +/- 0.11) x 10(6) M(-1)s(-1)] and to CH2=CHC4F9 [2.6 +/- 0.2) x 105 M(-1)s(-1)] at 25 degrees C. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(98)00568-7

文献信息

• METHODS FOR DELIVERING BIOACTIVE AGENTS
  申请人：——

  公开号：US20010051131A1

  公开（公告）日：2001-12-13

  Methods for enhancing the bioavailability of a bioactive agent in vivo. Embodiments of the invention involve administering a bioactive agent and an acoustically active composition to a patient. Ultrasound energy may be applied in an amount sufficient to activate the acoustically active composition. In preferred form, the acoustically active composition is administered to the patient at a rate which comprises continuous infusion.

  提高生物活性剂体内生物利用度的方法。本发明的实施方案包括向患者施用生物活性剂和声学活性组合物。施加的超声波能量足以激活声学活性组合物。在优选的形式中，声学活性组合物以连续输注的方式给患者用药。
• US4617363A
  申请人：——

  公开号：US4617363A

  公开（公告）日：1986-10-14
• Reactivity of perfluoro-n-alkyl radicals with reluctant substrates. Rates of addition to RFCH2CH=CH2 and RFCH=CH2
  作者：Bruno Delest、Alexander B. Shtarev、William R. Dolbier

  DOI：10.1016/s0040-4020(98)00568-7

  日期：1998.8

  Conditions for conducting competitive experiments involving slow reactions of perfluoroalkyl radicals have been defined. A revised value for the rate constant for hydrogen abstraction from Et3SiH is reported [(5.0 +/- 0.4) x 10(5) M(-1)s(-1)], as we the rate, constants for addition of the n-C4F9. radical to CH2=CHCH2C4F9 [1.15 +/- 0.11) x 10(6) M(-1)s(-1)] and to CH2=CHC4F9 [2.6 +/- 0.2) x 105 M(-1)s(-1)] at 25 degrees C. (C) 1998 Elsevier Science Ltd. All rights reserved.