4-N-tert-butylphenyl-1,4-diamine | 21567-55-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4-N-tert-butylphenyl-1,4-diamine
• 英文别名: N1-(tert-butyl)benzene-1,4-diamine；N-tert.Butyl-p-phenylendiamin；N-tert-butylbenzene-1,4-diamine；N-(4-aminophenyl)-N-(tert-butyl)amine；4-N-tert-butylbenzene-1,4-diamine
• CAS: 21567-55-5
• 化学式: C₁₀H₁₆N₂
• 分子量: 164.25
• InChiKey: BNVWDYFZDRRQKF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  38
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-N-tert-butylphenyl-1,4-diamine 在 (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride 、 盐酸羟胺 、 caesium carbonate 、 4,5-双二苯基膦-9,9-二甲基氧杂蒽 作用下， 以 四氢呋喃 、 乙醇 、 水 、 甲苯 为溶剂， 生成 (E)-4-((4-(tert-butylamino)phenyl)amino)benzaldehyde oxime
  参考文献：
  名称：

  [EN] FERROPTOSIS INHIBITORS–DIARYLAMINE PARA-ACETAMIDES
  [FR] INHIBITEURS DE FERROPTOSE-DIARYLAMINE PARA-ACÉTAMIDES

  摘要：

  提供了抑制铁死亡活性的化合物，或调节或抑制与铁死亡失调相关的疾病，如神经病、缺血再灌注损伤、急性肾衰竭和癌症，包括相应的磺胺类化合物，以及其药用可接受的盐、水合物和立体异构体。这些化合物用于制备药物组合物，并且用于制备和使用方法，包括以有效剂量的化合物或组合物治疗需要的人，并检测人的健康或状况的改善。

  公开号：

  WO2021175200A1
• 作为产物：
  描述：

  4-溴-N,N-双(三甲基甲硅烷基)苯胺 在 盐酸 、 正丁基锂 作用下， 以 乙醚 、 氯仿 为溶剂， 反应 2.5h， 生成 4-N-tert-butylphenyl-1,4-diamine
  参考文献：
  名称：

  Imino- and bis-imino-pyridines with N-ter-butyl-N-aminoxyl group: synthesis, oxidation and use as ligand towards M2+ ( Mn, Ni, Zn) and Gd3+

  摘要：

  Imino- and bis-iminopyridine ligands bearing N-ter-butylhydroxy groups were synthesized by the condensation reaction between a Al-ter-butylhydroxy substituted aniline and 2-formylpyridine, 2-acetylpyridine and 2,6-bis-acetylpyridine. The N-ter-butylaminoxy radicals obtained after oxidation using PbO2 or Ag2O were studied by EPR spectroscopy in solution. Indeed, complete decomposition was observed during isolation of these radical derivatives. The N-ter-butylhydroxy substituted ligands obtained were complexed with Mn2+, Ni2+, Zn2+ and Gd3+ salts; the obtained complexes were characterized and oxidized to give the aminoxy analogs. which were studied using IR, UV and EPR spectroscopies. (C) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2004.09.014

文献信息

• TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS
  申请人：Tao Chunlin

  公开号：US20120172361A1

  公开（公告）日：2012-07-05

  Compounds of the formula (I) and formula (II) and pharmaceutically acceptable salts thereof.

  公式（I）和公式（II）的化合物及其药学上可接受的盐。
• Tert-alkyl-phenylenediamines
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0332038A2

  公开（公告）日：1989-09-13

  This invention relates to a class of tert-alkyl-para-­phenylenediamines having alkyl groups ortho to an amine group. More particularly, the aromatic diamines are represented by the formulas: wherein R₁, R₂ and R₃ are C₁₋₃ alkyl groups or R₂ and R₃ are combined to form a C₅₋₆ membered ring. The above described alkylated para-phenylenediamines have been found to be well suited for use as a chain extender in forming polyurethane/urea elastomer systems and provide enhanced benefits in terms of delayed reactivity for facilitating the processing of the elastomer systems, and high tensile strength, thermal stability and tear resistance in the resulting elastomer itself.

  本发明涉及一类叔烷基对苯二胺，其烷基正交于一个胺基。更具体地说，芳香族二胺由以下公式表示： 其中 R₁、R₂ 和 R₃ 是 C₁₋₃ 烷基或 R₂ 和 R₃ 结合形成一个 C₅₋₆ 成员环。 研究发现，上述烷基化对苯二胺非常适合用作形成聚氨酯/尿素弹性体体系的扩链剂，并可在延迟反应性方面提供更多益处，以促进弹性体体系的加工，并使所得弹性体本身具有较高的拉伸强度、热稳定性和抗撕裂性。
• Alkylation of toluenediamine and para-phenylenediamine with isobutylene in the presence of acidic, crystalline molecular sieves
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0350681A2

  公开（公告）日：1990-01-17

  This invention relates to an improvement in a process for producing tert-butyl-derivatives of aromatic amines, e.g., para-phenylenediamine and toluenediamine by the reaction of isobutylene with the corresponding aromatic diamine in the presence of a highly acidic crystalline alumino-silicate catalyst. The improvement constitutes adding sufficient water to the catalyst to provide at least partial saturation of the catalyst during the reaction.

  本发明涉及在高酸性结晶铝硅酸盐催化剂存在下，通过异丁烯与相应的芳香族二胺反应生产芳香族胺叔丁基衍生物（如对苯二胺和甲苯二胺）工艺的改进。改进的方法是在催化剂中加入足够的水，使催化剂在反应过程中至少达到部分饱和。
• Polyimide membranes and their use for gas separation
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0417770A1

  公开（公告）日：1991-03-20

  The present invention is a class of polyimide membranes wherein the diamine portion of the polymer structure is formed from 2,5-di-t-butyl-1,4-­phenylenediamine. Membranes formed from polyimides containing this diamine structure exhibit unexpectedly high gas permeability properties and are especially useful for separating oxygen from nitrogen or air.

  本发明是一类聚酰亚胺膜，其中聚合物结构的二胺部分由 2,5-二叔丁基-1,4-苯二胺形成。由含有这种二胺结构的聚酰亚胺形成的膜具有意想不到的高气体渗透性能，特别适用于从氮气或空气中分离氧气。
• MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：EP3623398A1

  公开（公告）日：2020-03-18

  A modified block copolymer according to the present invention is a modified block copolymer comprising a polymer block comprising a vinyl aromatic compound as a main constituent (A), a polymer block comprising a conjugate diene compound as a main constituent (B), and an atomic group having NHx (x = 0 to 2) (C). In the modified block copolymer, the polymer block comprising a conjugate diene compound as a main constituent (B) is a hydrogenated product, the atomic group having NHx (x = 0 to 2) (C) is contained in a side chain, and a compound forming the atomic group having NHx (x = 0 to 2) (C) satisfies the following condition: Condition: when the compound forming the atomic group having NHx (x = 0 to 2) (C) is reacted with a maleic anhydride-modified group in a maleic anhydride-modified block copolymer, a MFR value at 230°C under a load of 2.16 kg of the modified block copolymer after the reaction is 0.1 times or more a MFR value at 230°C under a load of 2.16 kg of the maleic anhydride-modified block copolymer before the reaction.

  根据本发明，改性嵌段共聚物是一种改性嵌段共聚物，包括以乙烯基芳香族化合物为主要成分的聚合物嵌段（A）、以共轭二烯化合物为主要成分的聚合物嵌段（B）和具有 NHx（x = 0 至 2）的原子团（C）。在改性嵌段聚合物中，由共轭二烯化合物作为主要成分（B）的聚合物嵌段是氢化产物，具有 NHx（x = 0 至 2）（C）的原子团包含在侧链中，形成具有 NHx（x = 0 至 2）（C）的原子团的化合物满足以下条件： 条件：当形成具有 NHx（x = 0 至 2）(C)的原子团的化合物与马来酸酐改性嵌段共聚物中的马来酸酐改性基团反应时，反应后在 230℃、负载 2.16 千克改性嵌段共聚物时的 MFR 值是反应前在 230℃、负载 2.16 千克马来酸酐改性嵌段共聚物时的 MFR 值的 0.1 倍或以上。