4,4'-bis(9,9-di-n-octylfluorene-2-yl)benzophenone | 1309606-91-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: 4,4'-bis(9,9-di-n-octylfluorene-2-yl)benzophenone
• CAS: 1309606-91-4
• 化学式: C₇₁H₉₀O
• 分子量: 959.495
• InChiKey: VQVOGLCFNUCPQJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  21.79
• 重原子数：
  72.0
• 可旋转键数：
  32.0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  17.07
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  4,4'-bis(9,9-di-n-octylfluorene-2-yl)benzophenone 、 丙二腈 在 四氯化钛 、 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以60%的产率得到1,1-bis(4,4'-bis(9,9-di-n-octylfluorene-2-yl)phenyl)-2,2-dicyanoethylene
  参考文献：
  名称：

  Highly Selective and Sensitive Detection of Cyanide by a Reaction-Based Conjugated Polymer Chemosensor

  摘要：

  Based on a specific nucleophilic addition reaction with cyanide, a dicyano-vinyl-containing conjugated polymer (P1) has been designed and synthesized as a colorimetric and fluorescent chemosensor for cyanide anion. The combination of advantages of both reaction-based sensors and conjugated polymer sensors offers its highly sensitive and selective recognition of CN-. The addition of CN- to P1 solution induced a change in the solution color from yellow-green to colorless, while no color change could be observed in presence of other common anions, by which CN- can be identified from other anions directly with the naked eye. At the same time, a 31.6-fold fluorescence quenching was achieved upon adding CN- into P1 solution. The fluorescence quenching has shown a linear response to CN- in the concentration range of 0.5-30 mu M. Furthermore, its detection limit for CN- can be as low as 14 ppb, which is among the best results for the fluorescent conjugated polymer-based cyanide chemosensors. Compared with its small molecular counterpart, P1 exhibits higher sensitivity and selectivity, wider linear region, and faster response.

  DOI：

  10.1021/ma2005684
• 作为产物：
  描述：

  4,4'-二溴二苯甲酮 、 9,9-dioctylfluorene-2-boronic acid bis(1,3-propanediol) ester 在 四(三苯基膦)钯 、 potassium carbonate 作用下， 以 甲苯 为溶剂， 反应 20.0h， 以80%的产率得到4,4'-bis(9,9-di-n-octylfluorene-2-yl)benzophenone
  参考文献：
  名称：

  Highly Selective and Sensitive Detection of Cyanide by a Reaction-Based Conjugated Polymer Chemosensor

  摘要：

  Based on a specific nucleophilic addition reaction with cyanide, a dicyano-vinyl-containing conjugated polymer (P1) has been designed and synthesized as a colorimetric and fluorescent chemosensor for cyanide anion. The combination of advantages of both reaction-based sensors and conjugated polymer sensors offers its highly sensitive and selective recognition of CN-. The addition of CN- to P1 solution induced a change in the solution color from yellow-green to colorless, while no color change could be observed in presence of other common anions, by which CN- can be identified from other anions directly with the naked eye. At the same time, a 31.6-fold fluorescence quenching was achieved upon adding CN- into P1 solution. The fluorescence quenching has shown a linear response to CN- in the concentration range of 0.5-30 mu M. Furthermore, its detection limit for CN- can be as low as 14 ppb, which is among the best results for the fluorescent conjugated polymer-based cyanide chemosensors. Compared with its small molecular counterpart, P1 exhibits higher sensitivity and selectivity, wider linear region, and faster response.

  DOI：

  10.1021/ma2005684