25,27-bis[(3-phthalimidopropyl)oxy]calix[4]arene-crown-6 | 252357-77-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 25,27-bis[(3-phthalimidopropyl)oxy]calix[4]arene-crown-6
• 英文别名: 2-[3-[[44-[3-(1,3-dioxoisoindol-2-yl)propoxy]-3,6,9,12,15,18-hexaoxahexacyclo[18.15.7.126,30.137,41.02,32.019,24]tetratetraconta-1,19,21,23,26,28,30(44),32,34,37(43),38,40-dodecaen-43-yl]oxy]propyl]isoindole-1,3-dione
• CAS: 252357-77-0
• 化学式: C₆₀H₆₀N₂O₁₂
• 分子量: 1001.14
• InChiKey: LUBFPPDDQJSFLY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.33
• 重原子数：
  74.0
• 可旋转键数：
  10.0
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  148.6
• 氢给体数：
  0.0
• 氢受体数：
  12.0

反应信息

• 作为反应物：
  描述：

  25,27-bis[(3-phthalimidopropyl)oxy]calix[4]arene-crown-6 在 一水合肼 作用下， 以 乙醇 为溶剂， 反应 10.0h， 以88%的产率得到25,27-bis[(3-aminopropyl)oxy]calix[4]arene-crown-6
  参考文献：
  名称：

  Facilitated Transport of Hydrophilic Salts by Mixtures of Anion and Cation Carriers and by Ditopic Carriers

  摘要：

  Anion transfer to the membrane phase affects the extraction efficiency of salt transport by cation carriers 1 and 3. Addition of anion receptors 5 or 6 to cation carriers 1, 3, or 3 in the membrane phase enhances the transport of salts under conditions in which the cation carriers alone do not transport salt. The extraction of salt by the carrier mixtures is larger than by cation or anion carrier only, but the rate of diffusion is lower. Ditopic receptors 8 and 9 transport CsCl or KCl much faster than monotopic anion receptor 7 or cation receptors 1 and 2. The faster transport is due to a higher extraction constant K-ex despite a lower diffusion constant of the ditopic salt complex.

  DOI：

  10.1021/ja991588g
• 作为产物：
  描述：

  二对甲苯磺酸戊乙二醇 、 25,27-bis[(3-phthalimidopropyl)oxy]-calix[4]arene 在 caesium carbonate 作用下， 以 乙腈 为溶剂， 反应 120.0h， 以78%的产率得到25,27-bis[(3-phthalimidopropyl)oxy]calix[4]arene-crown-6
  参考文献：
  名称：

  Facilitated Transport of Hydrophilic Salts by Mixtures of Anion and Cation Carriers and by Ditopic Carriers

  摘要：

  Anion transfer to the membrane phase affects the extraction efficiency of salt transport by cation carriers 1 and 3. Addition of anion receptors 5 or 6 to cation carriers 1, 3, or 3 in the membrane phase enhances the transport of salts under conditions in which the cation carriers alone do not transport salt. The extraction of salt by the carrier mixtures is larger than by cation or anion carrier only, but the rate of diffusion is lower. Ditopic receptors 8 and 9 transport CsCl or KCl much faster than monotopic anion receptor 7 or cation receptors 1 and 2. The faster transport is due to a higher extraction constant K-ex despite a lower diffusion constant of the ditopic salt complex.

  DOI：

  10.1021/ja991588g