Benzyl dicyclohexylphosphinyl acetate | 1186034-89-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzyl dicyclohexylphosphinyl acetate
• 英文别名: Benzyl 2-dicyclohexylphosphorylacetate
• CAS: 1186034-89-8
• 化学式: C₂₁H₃₁O₃P
• 分子量: 362.449
• InChiKey: ODCGMWPMBHVLDN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  dicyclohexylbromophosphine 、 2-溴乙酸苄酯 反应 72.0h， 生成 Benzyl dicyclohexylphosphinyl acetate
  参考文献：
  名称：

  Diarylphosphine- and dialkylphosphine-containing compounds, processes of preparing same and uses thereof as tridentate ligands

  摘要：

  公开了一种制备含有一个或多个二芳基膦和/或二烷基膦电子给体基团的三齿配体的新工艺。公开了使用该工艺制备这种三齿配体和含有同样三齿配体的有机金属配合物的组合化学库。进一步公开了新的含有二芳基膦和二烷基膦的化合物，可以作为三齿配体（例如夹子配体），这种三齿配体的组合化学库，含有这些配体（例如夹子配合物）的有机金属配合物和这些配合物的组合化学库。公开了利用这些库筛选候选有机金属催化剂的方法。还公开了用于制备三齿配体的新前体分子和制备这些分子的工艺。

  公开号：

  US08318960B2

文献信息

• NOVEL DIARYLPHOSPHINE- AND DIALKYLPHOSPHINE-CONTAINING COMPOUNDS, PROCESSES OF PREPARING SAME AND USES THEREOF AS TRIDENTATE LIGANDS
  申请人：GANDELMAN Mark

  公开号：US20100292084A1

  公开（公告）日：2010-11-18

  A novel process of preparing tridentate ligands containing one or more of a diarylphosphine and/or dialkylphosphine electron donating groups are disclosed. Use of this process for preparing a combinatorial library of such tridentate ligands and of organometallic complexes containing same is also disclosed. Further disclosed are novel diarylphosphine-containing and dialkylphosphine-containing compounds that can serve as tridentate ligands (e.g., pincer ligands), combinatorial libraries of such tridentate ligands, organometallic complexes containing these ligands (e.g., pincer complexes), and combinatorial libraries of such complexes. Methods utilizing these libraries for screening for candidate organometallic catalysts are also disclosed. Novel precursor molecules useful for preparing the tridentate ligands and processes of preparing same are also disclosed.

  本文公开了一种制备三齿配体的新工艺，其中包含一个或多个二芳基膦和/或二烷基膦电子给体基团。本工艺用于制备这种三齿配体和含有这种配体的有机金属配合物的组合库。还公开了新的含有二芳基膦和二烷基膦的化合物，可用作三齿配体（例如，夹子配体），这些三齿配体的组合库，含有这些配体的有机金属配合物（例如，夹子配合物）以及这些配合物的组合库。还公开了利用这些库筛选候选有机金属催化剂的方法。还公开了用于制备这种三齿配体的新前体分子和制备方法。
• US8318960B2
  申请人：——

  公开号：US8318960B2

  公开（公告）日：2012-11-27
• Diarylphosphine- and dialkylphosphine-containing compounds, processes of preparing same and uses thereof as tridentate ligands
  申请人：Technion Research & Development Foundation Ltd.

  公开号：US08318960B2

  公开（公告）日：2012-11-27

  A novel process of preparing tridentate ligands containing one or more of a diarylphosphine and/or dialkylphosphine electron donating groups are disclosed. Use of this process for preparing a combinatorial library of such tridentate ligands and of organometallic complexes containing same is also disclosed. Further disclosed are novel diarylphosphine-containing and dialkylphosphine-containing compounds that can serve as tridentate ligands (e.g., pincer ligands), combinatorial libraries of such tridentate ligands, organometallic complexes containing these ligands (e.g., pincer complexes), and combinatorial libraries of such complexes. Methods utilizing these libraries for screening for candidate organometallic catalysts are also disclosed. Novel precursor molecules useful for preparing the tridentate ligands and processes of preparing same are also disclosed.

  公开了一种制备含有一个或多个二芳基膦和/或二烷基膦电子给体基团的三齿配体的新工艺。公开了使用该工艺制备这种三齿配体和含有同样三齿配体的有机金属配合物的组合化学库。进一步公开了新的含有二芳基膦和二烷基膦的化合物，可以作为三齿配体（例如夹子配体），这种三齿配体的组合化学库，含有这些配体（例如夹子配合物）的有机金属配合物和这些配合物的组合化学库。公开了利用这些库筛选候选有机金属催化剂的方法。还公开了用于制备三齿配体的新前体分子和制备这些分子的工艺。