4-(2-diphenylphosphanylethylthio)benzoic acid | 1060676-12-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(2-diphenylphosphanylethylthio)benzoic acid
• 英文别名: 4-(2-Diphenylphosphanylethylsulfanyl)benzoic acid
• CAS: 1060676-12-1
• 化学式: C₂₁H₁₉O₂PS
• 分子量: 366.42
• InChiKey: JRJKIGKMOKSKDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  62.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(2-diphenylphosphanylethylthio)benzoic acid 、 氯甲酸异丁酯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 生成 C₂₆H₂₇O₄PS
  参考文献：
  名称：

  Pyrene-appended fluorescent tweezers generated via the Weak-Link Approach and their halide recognition properties

  摘要：

  Through the Weak-Link Approach, fluorescent condensed and open Cu(I) tweezer complexes were prepared and characterized. These complexes exhibit fluorescence-sensitive binding properties for halide anions. The solid-state structure of a non-fluorescent Rh(I) tweezer analogue, determined by X-ray crystallography, shows that the counter anion, Cl-, is trapped inbetween the two amide groups of the tweezer arms through hydrogen bonds. Although the tweezer binds Cl-, the open complex also binds Cl-, showing that the main role of the metal is to increase the local concentration of the pyrenyl amide moieties so that 2:1 binding can take place. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.05.047
• 作为产物：
  描述：

  4-巯基苯甲酸 、 2-氯乙基(二苯基)膦 在 18-冠醚-6 、 potassium carbonate 作用下， 以 水 、 乙腈 为溶剂， 以82%的产率得到4-(2-diphenylphosphanylethylthio)benzoic acid
  参考文献：
  名称：

  Pyrene-appended fluorescent tweezers generated via the Weak-Link Approach and their halide recognition properties

  摘要：

  Through the Weak-Link Approach, fluorescent condensed and open Cu(I) tweezer complexes were prepared and characterized. These complexes exhibit fluorescence-sensitive binding properties for halide anions. The solid-state structure of a non-fluorescent Rh(I) tweezer analogue, determined by X-ray crystallography, shows that the counter anion, Cl-, is trapped inbetween the two amide groups of the tweezer arms through hydrogen bonds. Although the tweezer binds Cl-, the open complex also binds Cl-, showing that the main role of the metal is to increase the local concentration of the pyrenyl amide moieties so that 2:1 binding can take place. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.05.047

文献信息

• Multi-State Dynamic Coordination Complexes Interconverted through Counterion-Controlled Phase Transfer
  作者：Ho Fung Cheng、McKinley K. Paul、Andrea I. d’Aquino、Charlotte L. Stern、Chad A. Mirkin

  DOI：10.1021/acs.inorgchem.0c03708

  日期：2021.4.5

  denticity of these complexes (mono- to bi-) can be modulated as they partition into different phases. In addition, we discovered that heteroligated complexes bearing ligands of different donor strengths preferentially rearrange into two homoligated complexes that are phase-partitioned to maximize the number of stronger coordination bonds. This behavior is not observed in systems with one solvent, highlighting

  我们研究了一系列动态弱链接方法（WLA）配合物，它们可以在两种不混溶的溶剂之间穿梭，并可以通过离子交换在两种结构状态之间切换。在这里，我们确定了疏水性阴离子将阳离子，两亲性络合物从水相转移到有机相，而氯离子源则逆转了这一过程。由于WLA配合物具有动态的金属配位特性，可以调节这些配合物（单-或双-）的密度，因为它们分配到不同的相中。另外，我们发现带有不同供体强度的配体的杂合配合物优先重排为两个均相配合物，这些相配合物被相分以最大化更强配位键的数量。在使用一种溶剂的系统中未观察到此行为，强调了多相溶剂环境中半不稳定配体的动态和刺激响应特性。综上所述，这项工作表明，高度可重构的WLA模式可以实现双相反应网络的设计或由直接的盐复分解反应驱动的化学分离。