1-Propanamine, 2,2,3,3-tetrafluoro-N-(triphenylphosphoranylidene)- | 906794-99-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Propanamine, 2,2,3,3-tetrafluoro-N-(triphenylphosphoranylidene)-
• CAS: 906794-99-8
• 化学式: C₂₁H₁₈F₄NP
• 分子量: 391.348
• InChiKey: FUDWEQBGTJJWQS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.06
• 重原子数：
  27.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  12.36
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  1-Propanamine, 2,2,3,3-tetrafluoro-N-(triphenylphosphoranylidene)- 、 对硝基苯甲醛 以 甲苯 为溶剂， 反应 48.0h， 以78.7%的产率得到(4-nitro-benzylidene)-(2,2,3,3-tetrafluoro-propyl)-amine
  参考文献：
  名称：

  Synthesis of fluorinated imines and carbodiimides from azides via aza-Wittig reaction

  摘要：

  The Staudinger reaction of fluoroalkylazides were studied. A series of N-fluoroalkylimines were synthesized via aza-Wittig reaction of N-fluoroalkyliminophosphoranes. The N,N'-difluoroalkylated carbodiimide was also synthesized via the reaction of N-fluoroalkyliminophosphoranes with carbon dioxide or carbon disulfide. (c) 2006 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2006.06.004
• 作为产物：
  描述：

  三苯基膦 、 2,2,3,3-tetrafluoropropylazide 以 乙醚 为溶剂， 反应 6.0h， 以98%的产率得到1-Propanamine, 2,2,3,3-tetrafluoro-N-(triphenylphosphoranylidene)-
  参考文献：
  名称：

  Synthesis of fluorinated imines and carbodiimides from azides via aza-Wittig reaction

  摘要：

  The Staudinger reaction of fluoroalkylazides were studied. A series of N-fluoroalkylimines were synthesized via aza-Wittig reaction of N-fluoroalkyliminophosphoranes. The N,N'-difluoroalkylated carbodiimide was also synthesized via the reaction of N-fluoroalkyliminophosphoranes with carbon dioxide or carbon disulfide. (c) 2006 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2006.06.004