acetaldehyde 4-nitrophenylhydrazone | 110380-43-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: acetaldehyde 4-nitrophenylhydrazone
• 英文别名: Acetaldehyd-4-nitrophenylhydrazon；N-[(E)-ethylideneamino]-4-nitroaniline
• CAS: 110380-43-3
• 化学式: C₈H₉N₃O₂
• 分子量: 179.178
• InChiKey: YVDNNYWGYXGGCI-XNWCZRBMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  70.2
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  acetaldehyde 4-nitrophenylhydrazone 以2%的产率得到
  参考文献：
  名称：

  CYBOPOB, N. N.;SHKILKOVA, V. N.;PODXALYUZINA, N. YA., ZH. ORGAN. XIMII, 1983, 19, N 11, 2420-2423

  摘要：

  DOI：
• 作为产物：
  描述：

  乙醛 、 4-硝基苯肼 以 硫酸 为溶剂， 生成 acetaldehyde 4-nitrophenylhydrazone
  参考文献：
  名称：

  Kaberia, Festus; Vickery, Brian; Willey, Gerald R., Journal of the Chemical Society. Perkin transactions II, 1980, # 11, p. 1622 - 1626

  摘要：

  DOI：

文献信息

• [EN] HELLEBRIN AND HELLEBRIGENIN DERIVATIVES<br/>[FR] HELLÉBRINE ET DÉRIVÉS D'HELLÉBRIGÉNINE
  申请人：UNIBIOSCREEN SA

  公开号：WO2010102673A1

  公开（公告）日：2010-09-16

  The present invention relates to new cardiotonic Steroid Compounds of Formula (I) or (II) wherein X1, X2, X3, L, R1, R2, R3, R4, and R5 have the same meaning as that defined in the Claims. The invention also relates to the use of said Compounds as medicaments, in particular in the treatment of Cancer.

  本发明涉及具有以下式（I）或（II）的新心力素类化合物，其中X1、X2、X3、L、R1、R2、R3、R4和R5的含义与权利要求中定义的含义相同。该发明还涉及将所述化合物用作药物，特别是用于癌症治疗。
• The Isoindazole Nucleus as a Donor in Fullerene-Based Dyads. Evidence for Electron Transfer
  作者：Juan L. Delgado、Pilar de la Cruz、Vicente López-Arza、Fernando Langa、David B. Kimball、Michael M. Haley、Yasuyuki Araki、Osamu Ito

  DOI：10.1021/jo0499017

  日期：2004.4.1

  A series of isoindazole-C-60 dyads 4a-c based on pyrazolino[60]fullerene have been prepared by 1,3-dipolar cycloadditions of the nitrile imines, generated in situ from hydrazones 3a-c, to C-60. Molecular orbital calculations for 4b revealed that the electron distribution of the HOMO is located on the isoindazole moiety, while the electron distribution of the LUMO is located on the C-60 moiety. Electrochemical properties of the new dyads 4a-c show a similar electron affinity with respect to C-60. Charge-transfer interactions in the ground state between the isoindazole ring and the fullerene cage are predicted by the molecular orbital calculations and confirmed by electrochemical studies in 4a,b. Steady-state fluorescence emission spectra of dyads 4a-c show that fluorescence intensities in polar benzonitrile solvent decrease with increasing electron-donating ability of the substituent attached on the isoindazole group. This was confirmed by the shortening of fluorescence lifetimes, from which intramolecular charge-separation rates and efficiencies via the excited singlet states of the fullerene moiety were evaluated. The yields of the triplet states in polar solvent decrease with the electron-donating ability, supporting the competitive formation of the charge-separated state with the intersystem crossing from the excited states. Thus, isoindazole[60]fullerene 4b can be considered a molecular switch with an AND logic gate.
• KABERIA F.; VICKERY B.; WILLEY G. R.; DREW M. G. B., J. CHEM. SOC. PERKIN TRANS., 1980, PART 2, NO 11, 1622-1626
  作者：KABERIA F.、 VICKERY B.、 WILLEY G. R.、 DREW M. G. B.

  DOI：——

  日期：——
• Kaberia, Festus; Vickery, Brian; Willey, Gerald R., Journal of the Chemical Society. Perkin transactions II, 1980, # 11, p. 1622 - 1626
  作者：Kaberia, Festus、Vickery, Brian、Willey, Gerald R.、Drew, Michael G. B.

  DOI：——

  日期：——
• CYBOPOB, N. N.;SHKILKOVA, V. N.;PODXALYUZINA, N. YA., ZH. ORGAN. XIMII, 1983, 19, N 11, 2420-2423
  作者：CYBOPOB, N. N.、SHKILKOVA, V. N.、PODXALYUZINA, N. YA.

  DOI：——

  日期：——