百日菊链格孢醇 | 17811-28-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 百日菊链格孢醇
• 英文名称: zinniol
• 英文别名: [2-(hydroxymethyl)-3-methoxy-4-methyl-5-(3-methylbut-2-enoxy)phenyl]methanol
• CAS: 17811-28-8
• 化学式: C₁₅H₂₂O₄
• 分子量: 266.337
• InChiKey: DUMQPTRUYCCSEZ-UHFFFAOYSA-N

物化性质

• 沸点：
  425.3±40.0 °C(Predicted)
• 密度：
  1.106±0.06 g/cm3(Predicted)
• LogP：
  2.070 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2909499000
• WGK Germany：
  3

反应信息

• 作为反应物：
  描述：

  百日菊链格孢醇 在 chromium(VI) oxide 、 甲醇 、 硫酸 、 potassium carbonate 作用下， 以 水 、 丙酮 为溶剂， 反应 0.08h， 生成 6-Hydroxymethyl-2-methoxy-3-methyl-4-(3-methyl-but-2-enyloxy)-benzoic acid
  参考文献：
  名称：

  Natural Zinniol Derivatives from Alternaria tagetica. Isolation, Synthesis, and Structure−Activity Correlation

  摘要：

  Two novel phytotoxins, 8-zinniol methyl ether (5) and 8-zinniol acetate (6), in addition to 6-(3',3'dimethylallyloxy)-4-methoxy-5-methylphthalide (2), 5-(3',3'-dimethylallyloxy)-7-methoxy-6-methylphthalide (3), and the novel metabolites 8-zinniol 2-(phenyl)ethyl ether (4) and 7-zinniol acetate (7) have been identified as natural zinniol derivatives from the organic crude extract of Alternaria tagetica culture filtrates. Using zinniol as the starting material, phytotoxin 5 was synthesized, together with a number of synthetic intermediates (8-13). Both natural and synthetic zinniol derivatives were evaluated in the leaf-spot bioassay against marigold leaves (Tagetes erecta).

  DOI：

  10.1021/jf010641t
• 作为产物：
  描述：

  methyl 2-formyl-3,5-dihydroxy-4-methylbenzoate 在 lithium aluminium tetrahydride 、 potassium carbonate 作用下， 以 乙醚 、 丙酮 为溶剂， 反应 21.5h， 生成 百日菊链格孢醇
  参考文献：
  名称：

  The synthesis of zinniol

  摘要：

  DOI：

  10.1016/s0040-4020(01)93696-8

文献信息

• Plant polynucleotides encoding prenyl proteases
  申请人：BASF Plant Science GmbH

  公开号：EP2157183A1

  公开（公告）日：2010-02-24

  The present invention provides novel polynucleotides encoding plant prenyl protease polypeptides, fragments and homologs thereof. Also provided arc vectors, host cells, antibodies, and recombinant methods for producing said polypeptides. The invention further provides novel polynucleotides encoding plant promoters, polypeptides, fragments and homologs thereof. The invention further relates to methods of applying these novel plant polypeptides to the identification, prevention, and/or conferment of resistence to various plant diseases and/or disorders, particularly drought resistence.

  本发明提供了编码植物前酰蛋白酶多肽、片段及其同源物的新型多核苷酸。还提供了用于生产所述多肽的弧形载体、宿主细胞、抗体和重组方法。本发明进一步提供了编码植物启动子、多肽、片段及其同源物的新型多核苷酸。本发明进一步涉及将这些新型植物多肽应用于鉴定、预防和/或赋予对各种植物病害和/或失调的抗性，特别是抗旱性的方法。
• Compositions and methods for improving skin health and for the treatment and prevention of diseases, disorders and conditions associated with pathogenic microbes
  申请人：DermBiont, Inc.

  公开号：US11040077B2

  公开（公告）日：2021-06-22

  Disclosed herein are compositions and methods for using human-derived Janthinobacterium lividum. Compositions improve skin health. Methods may include applying human-derived Janthinobacterium lividum over a host or host area, such as skin or mucosa, to minimize the presence of one or more microbes, maximize therapeutic effects, and/or improve health. A method to minimize a pathogenic microbe may include applying to a surface a composition including human-derived Janthinobacterium lividum and an acceptable carrier. Compositions and methods may include a prebiotic to maximize growth and/or metabolites. Compositions and methods may include human-derived Janthinobacterium lividum metabolites, such as violacein, prodigiosin, indole-3-carboxaldehyde, and lantibiotics, and/or other Postbiotics.

  本文公开了使用源自人类的 Lividum Janthinobacterium 的组合物和方法。组合物可改善皮肤健康。方法可包括在宿主或宿主区域（如皮肤或粘膜）上施用源于人的生发的Lividum Janthinobacterium，以最大限度地减少一种或多种微生物的存在，最大限度地提高治疗效果，和/或改善健康状况。减少病原微生物的方法可包括向表面施用一种组合物，该组合物包括来源于人类的Janthinobacterium lividum和一种可接受的载体。组合物和方法可包括益生元，以最大限度地提高生长和/或代谢物。组合物和方法可包括来源于人的猪蓝细菌代谢物，如violacein、prodigiosin、吲哚-3-甲醛、兰特益生菌和/或其他后益生菌。
• Modified tet-inducible system for regulation of gene expression in plants
  申请人：Golovko Andrei

  公开号：US20050034187A1

  公开（公告）日：2005-02-10

  The present invention relates to modified tetracycline-inducible cassettes for controlling gene expression in organisms, particularly plants. Specifically, the invention provides novel tetracycline repressor and operator cassettes. The invention preferably provides a tetracycline-inducible expression cassette comprising both the tetracycline repressor and operator cassettes of the present invention wherein the repressor and operator cassettes are located on a single plasmid and/or vector. Also provided is a method of producing herbicide resistant plants using the modified tetracycline inducible cassettes of the present invention to control the expression of a herbicide resistance gene. Moreover, a method for identifying novel tetracycline analogs and/or functional equivalents using the modified tetracycline inducible cassettes of the present invention is also presented.

  本发明涉及用于控制生物，特别是植物基因表达的改良四环素诱导盒。具体地说，本发明提供了新型的四环素抑制剂和操作盒。本发明优选提供一种四环素诱导表达盒，该表达盒包括本发明的四环素抑制剂和操作者盒，其中抑制剂和操作者盒位于单个质粒和/或载体上。还提供了一种生产抗除草剂植物的方法，使用本发明的改良四环素诱导盒控制抗除草剂基因的表达。此外，还介绍了一种利用本发明的修饰四环素诱导盒鉴定新型四环素类似物和/或功能等效物的方法。
• Hariprakasha; Subba Rao, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1998, vol. 37, # 9, p. 851 - 856
  作者：Hariprakasha、Subba Rao

  DOI：——

  日期：——
• The structure of zinnolide, a new phytotoxin from Alternaria solani.
  作者：Akitami ICHIHARA、Hiroyuki TAZAKI、Sadao SAKAMURA

  DOI：10.1271/bbb1961.49.2811

  日期：——