6,6'-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-2,2'-bis-methoxymethoxy-[1,1']binaphthalenyl | 321850-56-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 6,6'-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-2,2'-bis-methoxymethoxy-[1,1']binaphthalenyl
• 英文别名: Tert-butyl-[4-[5-[6-[4-[tert-butyl(dimethyl)silyl]oxybutyl]-2-(methoxymethoxy)naphthalen-1-yl]-6-(methoxymethoxy)naphthalen-2-yl]butoxy]-dimethylsilane；tert-butyl-[4-[5-[6-[4-[tert-butyl(dimethyl)silyl]oxybutyl]-2-(methoxymethoxy)naphthalen-1-yl]-6-(methoxymethoxy)naphthalen-2-yl]butoxy]-dimethylsilane
• CAS: 321850-56-0
• 化学式: C₄₄H₆₆O₆Si₂
• 分子量: 747.175
• InChiKey: VFGIHEMHRXSPNT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.31
• 重原子数：
  52
• 可旋转键数：
  21
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  6,6'-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-2,2'-bis-methoxymethoxy-[1,1']binaphthalenyl 在 sodium tetrahydroborate 、 叔丁基锂 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 生成 {6,6'-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-2,2'-bis-methoxymethoxy-[1,1']binaphthalenyl-3-yl}-methanol
  参考文献：
  名称：

  Immobilization of asymmetric multifunctional catalysts on an insoluble polymer

  摘要：

  Polymer-supported linked-BINOL was synthesized to immobilize asymmetric catalysts with two BINOL units. The advantage of the polymer-supported linked-BINOL over randomly polymer-supported BINOL was confirmed by asymmetric Michael reaction. A novel polymer-supported La-Zn-linked-BINOL complex afforded the Michael adduct in good yield and moderate ee. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01486-6
• 作为产物：
  描述：

  (S)-6,6'-dibromo-1,1'-binaphthalene-2,2'-diol 在 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 6,6'-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-2,2'-bis-methoxymethoxy-[1,1']binaphthalenyl
  参考文献：
  名称：

  Immobilization of asymmetric multifunctional catalysts on an insoluble polymer

  摘要：

  Polymer-supported linked-BINOL was synthesized to immobilize asymmetric catalysts with two BINOL units. The advantage of the polymer-supported linked-BINOL over randomly polymer-supported BINOL was confirmed by asymmetric Michael reaction. A novel polymer-supported La-Zn-linked-BINOL complex afforded the Michael adduct in good yield and moderate ee. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01486-6

文献信息

• Immobilization of asymmetric multifunctional catalysts on an insoluble polymer
  作者：Shigeki Matsunaga、Takashi Ohshima、Masakatsu Shibasaki

  DOI：10.1016/s0040-4039(00)01486-6

  日期：2000.10

  Polymer-supported linked-BINOL was synthesized to immobilize asymmetric catalysts with two BINOL units. The advantage of the polymer-supported linked-BINOL over randomly polymer-supported BINOL was confirmed by asymmetric Michael reaction. A novel polymer-supported La-Zn-linked-BINOL complex afforded the Michael adduct in good yield and moderate ee. (C) 2000 Elsevier Science Ltd. All rights reserved.