[2,6-Bis[4-(bromomethyl)phenyl]benzoyl]oxymethyl 2,6-bis[4-(bromomethyl)phenyl]benzoate | 167500-46-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2,6-Bis[4-(bromomethyl)phenyl]benzoyl]oxymethyl 2,6-bis[4-(bromomethyl)phenyl]benzoate
• CAS: 167500-46-1
• 化学式: C₄₃H₃₂Br₄O₄
• 分子量: 932.341
• InChiKey: GLRGFRCOHKIXIV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.2
• 重原子数：
  51
• 可旋转键数：
  14
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  [2,6-Bis[4-(bromomethyl)phenyl]benzoyl]oxymethyl 2,6-bis[4-(bromomethyl)phenyl]benzoate 在 sodium sulfide 作用下， 以 乙醇 、 苯 为溶剂， 反应 4.0h， 以40%的产率得到35,37-dioxa-7,23-dithiaoctacyclo[15.15.7.22,5.29,12.218,21.225,28.013,39.029,33]heptatetraconta-1(33),2(47),3,5(46),9,11,13(39),14,16,18(43),19,21(42),25,27,29,31,40,44-octadecaene-34,38-dione
  参考文献：
  名称：

  2′-Substituted meta-terphenyls as building blocks for cyclophanes with intra-annular functionality

  摘要：

  2'-Substituted m-terphenyls containing chloromethyl and/or thiomethyl groups at the 4,4'' or 3,3'' positions are used as building blocks for cyclophanes with intra-annular functionality. Syntheses are short and yields are good. The methodology, capable of wide structural variation, has been adapted to bi- and tricyclic cyclophanes.

  DOI：

  10.1016/0040-4020(94)01016-s
• 作为产物：
  描述：

  2,6-Bis(4-methylphenyl)benzoyl chloride 在 N-溴代丁二酰亚胺(NBS) 、 sodium hydride 作用下， 以 四氯化碳 为溶剂， 生成 [2,6-Bis[4-(bromomethyl)phenyl]benzoyl]oxymethyl 2,6-bis[4-(bromomethyl)phenyl]benzoate
  参考文献：
  名称：

  2′-Substituted meta-terphenyls as building blocks for cyclophanes with intra-annular functionality

  摘要：

  2'-Substituted m-terphenyls containing chloromethyl and/or thiomethyl groups at the 4,4'' or 3,3'' positions are used as building blocks for cyclophanes with intra-annular functionality. Syntheses are short and yields are good. The methodology, capable of wide structural variation, has been adapted to bi- and tricyclic cyclophanes.

  DOI：

  10.1016/0040-4020(94)01016-s

文献信息

• 2′-Substituted meta-terphenyls as building blocks for cyclophanes with intra-annular functionality
  作者：Harold Hart、Perumal Rajakumar

  DOI：10.1016/0040-4020(94)01016-s

  日期：1995.1

  2'-Substituted m-terphenyls containing chloromethyl and/or thiomethyl groups at the 4,4'' or 3,3'' positions are used as building blocks for cyclophanes with intra-annular functionality. Syntheses are short and yields are good. The methodology, capable of wide structural variation, has been adapted to bi- and tricyclic cyclophanes.