(9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid (S)-2-hexadecanoyloxy-3-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-propyl ester | 121249-84-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: (9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid (S)-2-hexadecanoyloxy-3-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-propyl ester
• 英文别名: 1-18:3-2-16:0-Monogalactosyldiacylglycerol；[(2S)-2-hexadecanoyloxy-3-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropyl] (9Z,12Z,15Z)-octadeca-9,12,15-trienoate
• CAS: 121249-84-1
• 化学式: C₄₃H₇₆O₁₀
• 分子量: 753.07
• InChiKey: OYPVEICJGOKWFP-FAFOYRQUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.2
• 重原子数：
  53
• 可旋转键数：
  36
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  152
• 氢给体数：
  4
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  (9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid (S)-2-hexadecanoyloxy-3-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-propyl ester 在 Rhizopus arrhizus lipase 、 boric acid-borax buffer 、 Triton X-100 作用下， 以 水 为溶剂， 反应 1.0h， 生成 Hexadecanoic acid (R)-1-hydroxymethyl-2-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-ethyl ester 、 (2S)-1-O-β-D-galactopyranosyl-3-O-palmitoyl glyceride
  参考文献：
  名称：

  Enzymatic transformation of glyceroglycolipids into sn-1 and sn-2 lysoglyceroglycolipids by use of Rhizopus arrhizus lipase

  摘要：

  Lipase from Rhizopus arrhizus catalyzed deacylation of two classes of glyceroglycolipids, monogalactosyl diacylglycerol(MGDG), and digalactosyl diacylglycerol(DGDG), proceeded regiospecifically to furnish sn-1 lysoglyceroglycolipids quantitatively. The lipase also catalyzed complete acyl migration of sn-1 lysoglycerogalacto-lipids leading to sn-2 lysoglycerogalactolipids.

  DOI：

  10.1016/s0040-4020(01)85063-8

文献信息

• Enzymatic transformation of glyceroglycolipids into sn-1 and sn-2 lysoglyceroglycolipids by use of Rhizopus arrhizus lipase
  作者：Nobutoshi Murakami、Takashi Morimoto、Hideaki Imamura、Akito Nagatsu、Jinsaku Sakakibara

  DOI：10.1016/s0040-4020(01)85063-8

  日期：1994.2

  Lipase from Rhizopus arrhizus catalyzed deacylation of two classes of glyceroglycolipids, monogalactosyl diacylglycerol(MGDG), and digalactosyl diacylglycerol(DGDG), proceeded regiospecifically to furnish sn-1 lysoglyceroglycolipids quantitatively. The lipase also catalyzed complete acyl migration of sn-1 lysoglycerogalacto-lipids leading to sn-2 lysoglycerogalactolipids.