2-amino-6-(1,2-dihydroxy-propyl)-3H,8H-pteridine-4,7-dione | 490-58-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• 英文名称: 2-amino-6-(1,2-dihydroxy-propyl)-3H,8H-pteridine-4,7-dione
• 英文别名: 2-Amino-6-(1,2-dihydroxy-propyl)-3H,8H-pteridin-4,7-dion；Ichthyopterin；2-amino-6-(1,2-dihydroxypropyl)-3,8-dihydropteridine-4,7-dione
• CAS: 490-58-4；18503-56-5；23259-60-1；141783-04-2；141783-05-3；141783-06-4
• 化学式: C₉H₁₁N₅O₄
• 分子量: 253.217
• InChiKey: IZMMJLZUJAZKES-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.4
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  149
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-amino-6-(1,2-dihydroxy-propyl)-3H,8H-pteridine-4,7-dione 在 potassium metaperiodate 、 溶剂黄146 作用下， 生成 2-amino-4,7-dioxo-3,4,7,8-tetrahydro-pteridine-6-carbaldehyde
  参考文献：
  名称：

  Tschesche; Glaser, Chemische Berichte, 1958, vol. 91, p. 2081,2085

  摘要：

  DOI：
• 作为产物：
  描述：

  乙酰丙酮酸乙酯 在 吗啉 、 甲醇 、 sodium tetrahydroborate 、 selenium(IV) oxide 、 sodium carbonate 、 溶剂黄146 作用下， 生成 2-amino-6-(1,2-dihydroxy-propyl)-3H,8H-pteridine-4,7-dione
  参考文献：
  名称：

  Tschesche; Glaser, Chemische Berichte, 1958, vol. 91, p. 2081,2085

  摘要：

  DOI：

文献信息

• Anti-Inflammatory and Anti-Allergy Extracts from Nettle
  申请人：Alberte Randall S.

  公开号：US20100009927A1

  公开（公告）日：2010-01-14

  The present invention relates in part to nettle extracts that are useful for treating or preventing seasonal allergies, allergic rhinitis, and other inflammatory conditions.
• Extracts of Cranberry and Methods of Using Thereof
  申请人：Alberte Randall S.

  公开号：US20100028469A1

  公开（公告）日：2010-02-04

  The present disclosure relates in part to extracts of cranberry ( Vaccinium macrocarpon ) comprising an enriched amount of certain compounds having anti-infective activity, e.g. antibacterial and/or antifungal activity, e.g. activity against C. albicans . Another aspect of the disclosure relates to combined cranberry and cinnamon extracts. In certain embodiments, these combined extracts have been optimized to control urinary tract infections caused by E. coli, S. aureus and C. albicans . Certain embodiments of the extract are enriched in bioactive compounds that have been shown to inhibit C. albicans adhesion and/or biofilm formation and its growth in vitro. In another aspect of the disclosure, the extracts are enriched in bioactives derived from cranberry and cinnamon that have been shown to inhibit the attachment and the growth of common urinary tract pathogens like E. coli, S. aureus and C. albicans.
• Tschesche; Glaser, Chemische Berichte, 1958, vol. 91, p. 2081,2085
  作者：Tschesche、Glaser

  DOI：——

  日期：——