N-trifluoromethylsulfonyl-S-amino-S-p-chlorophenylsulfoximide | 109139-28-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-trifluoromethylsulfonyl-S-amino-S-p-chlorophenylsulfoximide
• 英文别名: N-[amino-(4-chlorophenyl)-oxo-lambda6-sulfanylidene]-1,1,1-trifluoromethanesulfonamide；N-[amino-(4-chlorophenyl)-oxo-λ6-sulfanylidene]-1,1,1-trifluoromethanesulfonamide
• CAS: 109139-28-8
• 化学式: C₇H₆ClF₃N₂O₃S₂
• 分子量: 322.716
• InChiKey: YSJODMYRQGLNSM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  106
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  N-trifluoromethylsulfonyl-S-amino-S-p-chlorophenylsulfoximide 在 硫酸 作用下， 反应 2.0h， 生成 4-氯苯磺酰胺 、 三氟甲磺酰胺
  参考文献：
  名称：

  Kondratenko, N. V.; Popov, V. I.; Radchenko, O. A., Journal of Organic Chemistry USSR (English Translation), 1986, p. 1542 - 1547

  摘要：

  DOI：
• 作为产物：
  描述：

  4-chloro-N-(trifluoromethysulfonyl)benzenesulfonimidoyl fluoride 在 硫酸 、 氨 作用下， 生成 N-trifluoromethylsulfonyl-S-amino-S-p-chlorophenylsulfoximide
  参考文献：
  名称：

  The unusual reactivity of the mono- and bis- N-(trifluoromethylsulfonyl)-substituted azaanalogs of arenesulfonochlorides

  摘要：

  The reactions of N-(trifluoromethylsulfonyl)arenesulfonimidoyl- and N, N'- bis(trifluoromethylsulfonyl)arenesulfonodiimidoyl chlorides of general formulas Ar-S(0)(=NSO2CF3)Cl (1) and Ar-S(=NSO2CF3)(2)Cl (2) with ammonia have been investigated and found to yield the ammonium salts of [N-(trifluoromethylsulfonyl)arenesulfinylimino]-N' (trifluoromethylsulfonyl)amides. The high oxidative ability of the chlorides (1,2) have been shown. Thus, chlorides (2) react with benzene or trifluoromethylbenzene, to form the chlorobenzene or 3-chloro- trifluoromethylbenzene. The fluorides of the general formulas Ar-S(0)(=NSO2CF3)F and Ar-S(=NSO2CF3)(2)F have been prepared. Their interaction with ammonia leads to the usual formation of corresponding amides. The electron nature of new electron withdrawing substituents have been investigated.

  DOI：

  10.1016/s0040-4020(01)81341-7

文献信息

• Yagupol'skii, L. M.; Kondratenko, N. V.; Iksanova, S. V., Russian Journal of Organic Chemistry, 1995, vol. 31, # 5, p. 691 - 695
  作者：Yagupol'skii, L. M.、Kondratenko, N. V.、Iksanova, S. V.

  DOI：——

  日期：——
• Garlyauskajte Romute Yu., Sereda Sergej V., Yagupolskii Lev M., Tetrahedron, 50 (1994) N 23, S 6891-6906
  作者：Garlyauskajte Romute Yu., Sereda Sergej V., Yagupolskii Lev M.

  DOI：——

  日期：——
• KONDRATENKO N. V.; POPOV V. I.; RADCHENKO O. A.; IGANTEV N. V.; YAGUPOLSK+, ZH. ORGAN. XIMII, 22,(1986) N 8, 1716-1721
  作者：KONDRATENKO N. V.、 POPOV V. I.、 RADCHENKO O. A.、 IGANTEV N. V.、 YAGUPOLSK+

  DOI：——

  日期：——
• The unusual reactivity of the mono- and bis- N-(trifluoromethylsulfonyl)-substituted azaanalogs of arenesulfonochlorides
  作者：Romute Yu. Garlyauskajte、Sergej V. Sereda、Lev M. Yagupolskii

  DOI：10.1016/s0040-4020(01)81341-7

  日期：1994.1

  The reactions of N-(trifluoromethylsulfonyl)arenesulfonimidoyl- and N, N'- bis(trifluoromethylsulfonyl)arenesulfonodiimidoyl chlorides of general formulas Ar-S(0)(=NSO2CF3)Cl (1) and Ar-S(=NSO2CF3)(2)Cl (2) with ammonia have been investigated and found to yield the ammonium salts of [N-(trifluoromethylsulfonyl)arenesulfinylimino]-N' (trifluoromethylsulfonyl)amides. The high oxidative ability of the chlorides (1,2) have been shown. Thus, chlorides (2) react with benzene or trifluoromethylbenzene, to form the chlorobenzene or 3-chloro- trifluoromethylbenzene. The fluorides of the general formulas Ar-S(0)(=NSO2CF3)F and Ar-S(=NSO2CF3)(2)F have been prepared. Their interaction with ammonia leads to the usual formation of corresponding amides. The electron nature of new electron withdrawing substituents have been investigated.
• Kondratenko, N. V.; Popov, V. I.; Radchenko, O. A., Journal of Organic Chemistry USSR (English Translation), 1986, p. 1542 - 1547
  作者：Kondratenko, N. V.、Popov, V. I.、Radchenko, O. A.、Ignat'ev, N. V.、Yagupol'skii, L. M.

  DOI：——

  日期：——