tert-butyl 9-xanthenyl ketone | 137144-20-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: tert-butyl 9-xanthenyl ketone
• 英文别名: 2,2-Dimethyl-1-(9H-xanthen-9-YL)propan-1-one
• CAS: 137144-20-8
• 化学式: C₁₈H₁₈O₂
• 分子量: 266.34
• InChiKey: YKJAZOKXJFZKNW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  呫吨-9-甲酸 在 氯化亚砜 、 叔丁基锂 作用下， 以 乙醚 、 正戊烷 、 苯 为溶剂， 反应 3.5h， 生成 tert-butyl 9-xanthenyl ketone
  参考文献：
  名称：

  Rochlin, Elimelech; Rappoport, Zvi, Journal of the American Chemical Society, 1992, vol. 114, # 1, p. 230 - 241

  摘要：

  DOI：

文献信息

• MULTI-RING COMPOUNDS AND USES THEREOF
  申请人：Ohler Norman E.

  公开号：US20100249111A1

  公开（公告）日：2010-09-30

  Chemical agents, such as derivatives of hydroxy benzene moieties, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulate the activity of enzymes and structural polypeptides present in cells, such as cancer cells, or where the agents modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.

  本发明涉及化学制剂，例如羟基苯基衍生物及类似的杂环环结构，包括其盐，其作为抗癌和抗肿瘤制剂，特别是这些制剂调节细胞中的酶和结构多肽的活性，例如癌细胞，或这些制剂调节细胞系统中的基因表达水平，包括癌细胞等。本发明还涉及制备这些制剂的方法，以及包含这些制剂作为活性成分的制药组合物和使用这些制剂作为治疗剂的方法。
• Image making medium
  申请人：——

  公开号：US20030035917A1

  公开（公告）日：2003-02-20

  The invention relates to an image support medium for creation of an aesthetic image that is an work or object for display. This support medium includes a polymer in an amount sufficient to enable the image to have at least one aesthetic element. In different embodiments, the image support medium is an image support stabilizer, the polymer is a synthetic absorbent or conductive polymer, or the polymer is a transparent or synthetic translucent polymer and a property of this transparent or translucent polymer is enhanced to facilitate the creation or preservation of the image by at least one stabilizer. The invention also relates to a method for preparing this image support medium. The method includes forming a reaction mixture comprising a monomer in an amount sufficient to provide or enable the image to have an aesthetic element, and processing the reaction mixture into a 2- or 3-dimensional shape.

  本发明涉及一种图像支持介质，用于创建作为作品或展示对象的美学图像。这种支撑介质包括一种聚合物，其用量足以使图像具有至少一种审美元素。在不同的实施例中，图像支持介质是一种图像支持稳定剂，聚合物是一种合成的吸收性或导电性聚合物，或者聚合物是一种透明或合成的半透明聚合物，并且这种透明或半透明聚合物的特性被至少一种稳定剂增强，以促进图像的创建或保存。本发明还涉及一种制备这种图像支持介质的方法。该方法包括形成由单体组成的反应混合物，其用量足以提供或使图像具有美学元素，并将反应混合物加工成 2 维或 3 维形状。
• Hydroxypiperidine Derivatives and Uses Thereof
  申请人：Ohler Norman E.

  公开号：US20090036429A1

  公开（公告）日：2009-02-05

  Chemical agents, such as derivatives of hydroxypiperidine moieties, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulate the activity of enzymes and structural polypeptides present in cells, such as cancer cells, or where the agents modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.
• Hydroxypiperidine derivatives and uses thereof
  申请人：Ohler Norman E.

  公开号：US20110178066A1

  公开（公告）日：2011-07-21

  Chemical agents, such as derivatives of hydroxypiperidine moieties, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulate the activity of enzymes and structural polypeptides present in cells, such as cancer cells, or where the agents modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.
• US7629400B2
  申请人：——

  公开号：US7629400B2

  公开（公告）日：2009-12-08