3-bromo-2-(bromomethyl)-1,1-diphenylprop-1-ene | 161152-93-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-bromo-2-(bromomethyl)-1,1-diphenylprop-1-ene
• 英文别名: [3-Bromo-2-(bromomethyl)-1-phenylprop-1-enyl]benzene
• CAS: 161152-93-8
• 化学式: C₁₆H₁₄Br₂
• 分子量: 366.095
• InChiKey: BLFKHHLYRRXOGM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-甲基-1,1-二苯基丙烯 在 N-溴代丁二酰亚胺(NBS) 、 silica gel 作用下， 以 四氯化碳 、 乙酸乙酯 、 Petroleum ether 为溶剂， 反应 10.0h， 以54%的产率得到3-bromo-2-(bromomethyl)-1,1-diphenylprop-1-ene
  参考文献：
  名称：

  Acetoxylation and Hydroxylation of Diarylmethylenecycloalkanes via Radical Approach

  摘要：

  Diarylmethylenecycloalkanes were acetoxylated under the radical reaction conditions with PhI(OAc)(2), I-2, and TsNH2. Moreover, upon treating the products from the reactions of methylenecyclobutanes with N-bromosuccinimide (NBS) through silica gel column chromatography, the corresponding substituted methylenecyclobutanols were obtained in moderate to good yields. The plausible mechanisms have been proposed on the basis of the control experiments.

  DOI：

  10.1021/jo9027209

文献信息

• Acetoxylation and Hydroxylation of Diarylmethylenecycloalkanes via Radical Approach
  作者：Min Jiang、Yin Wei、Min Shi

  DOI：10.1021/jo9027209

  日期：2010.4.16

  Diarylmethylenecycloalkanes were acetoxylated under the radical reaction conditions with PhI(OAc)(2), I-2, and TsNH2. Moreover, upon treating the products from the reactions of methylenecyclobutanes with N-bromosuccinimide (NBS) through silica gel column chromatography, the corresponding substituted methylenecyclobutanols were obtained in moderate to good yields. The plausible mechanisms have been proposed on the basis of the control experiments.