1-(2,2,2-Trichlor-1-hydroxyethoxy)-propandiol-2,3 | 4087-34-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1-(2,2,2-Trichlor-1-hydroxyethoxy)-propandiol-2,3
• 英文别名: 3-(2,2,2-trichloro-1-hydroxy-ethoxy)-propane-1,2-diol；3-(2,2,2-Trichloro-1-hydroxyethoxy)propane-1,2-diol；3-(2,2,2-trichloro-1-hydroxyethoxy)propane-1,2-diol
• CAS: 4087-34-7
• 化学式: C₅H₉Cl₃O₄
• 分子量: 239.483
• InChiKey: YEBXYVIOSKIIED-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  69.9
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  三氯乙醛 、 甘油 生成 1-(2,2,2-Trichlor-1-hydroxyethoxy)-propandiol-2,3
  参考文献：
  名称：

  Hesse; Moll; Augustin, Journal fur praktische Chemie (Leipzig 1954), 1974, vol. 316, # 2, p. 304 - 314

  摘要：

  DOI：

文献信息

• Clearing agent and mounting media for microscopy
  申请人：Rutgers, The State University of New Jersey

  公开号：US10018540B2

  公开（公告）日：2018-07-10

  A clearing agent and mounting solution for microscopy is disclosed comprising at least trichloroethanol and/or derivatives thereof, where the refractive index of the solution is greater than or equal to about 1.3810. Also disclosed are methods of preparing specimens for microscopy.

  本发明公开了一种用于显微镜检查的显影剂和装片溶液，至少包含三氯乙醇和/或其衍生物，其中溶液的折射率大于或等于约 1.3810。还公开了显微镜标本的制备方法。
• Clearing agent and mounting medium for microscopy
  申请人：Rutgers, The State University of New Jersey

  公开号：US10067041B2

  公开（公告）日：2018-09-04

  A clearing agent and mounting solution for microscopy is disclosed comprising (a) trichloroethanol, (b) optionally, trichloroacetic acid, (c) optionally, glycerol and (d) optionally, water, where the refractive index of the solution is greater than or equal to about 1.3810. The solution can further comprise a C1-C6 alcohol, other acids, and/or a stain. The solution can also comprise derivatives and/or analogs of 2,2,2-trichloroethanol and/or trichloroacetic acid. Also disclosed is a method of preparing specimens for microscopy comprising (a) applying a specimen to a microscope slide or a cuvette, (b) applying a quantity of the above solution sufficient to mount the specimen, and (c) optionally applying a cover slip. The solution can be used effectively with stains or dyes, and with fresh, partially dry or dried materials, and for temporary or semi-permanent to permanent mounting. The solution can be used with specimens or tissues/cells/parts originating from animals, poultry, livestock, humans, higher plants, yeasts, molds, microorganisms, insects, mites, or reptiles.

  本发明公开了一种用于显微镜检查的显影剂和装片溶液，包括 (a) 三氯乙醇、(b) 可选的三氯乙酸、(c) 可选的甘油和 (d) 可选的水，其中溶液的折射率大于或等于约 1.3810。溶液还可进一步包含 C1-C6 醇、其他酸和/或染色剂。溶液中还可以包含 2,2,2-三氯乙醇和/或三氯乙酸的衍生物和/或类似物。还公开了一种制备显微镜观察标本的方法，包括：(a) 将标本置于显微镜载玻片或比色皿中；(b) 涂上一定量的上述溶液以装载标本；(c) 可选地涂上一层盖玻片。本溶液可有效用于染色剂或染料，以及新鲜、半干或干燥的材料，并可用于临时或半永久至永久装片。该溶液可用于来自动物、家禽、家畜、人类、高等植物、酵母、霉菌、微生物、昆虫、螨虫或爬行动物的标本或组织/细胞/部件。
• CLEARING AGENT AND MOUNTING MEDIUM FOR MICROSCOPY
  申请人：Rutgers, The State University of New Jersey

  公开号：EP2836812A1

  公开（公告）日：2015-02-18
• CLEARING AGENT AND MOUNTING MEDIA FOR MICROSCOPY
  申请人：Rutgers, The State University of New Jersey

  公开号：EP3519794A1

  公开（公告）日：2019-08-07
• Clearing Agent and Mounting Medium for Microscopy
  申请人：Rutgers, The State University of New Jersey

  公开号：US20150147779A1

  公开（公告）日：2015-05-28

  A clearing agent and mounting solution for microscopy is disclosed comprising (a) trichloroethanol, (b) optionally, trichloroacetic acid, (c) optionally, glycerol and (d) optionally, water, where the refractive index of the solution is greater than or equal to about 1.3810. The solution can further comprise a C1-C6 alcohol, other acids, and/or a stain. The solution can also comprise derivatives and/or analogs of 2,2,2-trichloroethanol and/or trichloroacetic acid. Also disclosed is a method of preparing specimens for microscopy comprising (a) applying a specimen to a microscope slide or a cuvette, (b) applying a quantity of the above solution sufficient to mount the specimen, and (c) optionally applying a cover slip. The solution can be used effectively with stains or dyes, and with fresh, partially dry or dried materials, and for temporary or semi-permanent to permanent mounting. The solution can be used with specimens or tissues/cells/parts originating from animals, poultry, livestock, humans, higher plants, yeasts, molds, microorganisms, insects, mites, or reptiles.