N-(p-bromophenyl)-N'-trimethylsilylurea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(p-bromophenyl)-N'-trimethylsilylurea
• 英文别名: 1-(4-Bromophenyl)-3-trimethylsilylurea
• 化学式: C₁₀H₁₅BrN₂OSi
• 分子量: 287.231
• InChiKey: BJZZXMPBYIEBOT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.41
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  41.1
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-(p-bromophenyl)-N'-trimethylsilylurea 以 乙醚 、 水 为溶剂， 以50%的产率得到4-溴苯基脲
  参考文献：
  名称：

  Reaction of Phenylurea and N-Trimethylsilyl-N'-phenylurea with Vanadocene and N-Bromosuccinimide

  摘要：

  Phenylurea and N-trimethylsilyl-N'-phenylurea react with vanadocene (Cp2V) in toluene to,give N-(eta(5)-cyclopentadienyl)vanadio-N'-phenylurea as a major product and Cp2VN=C=O and aniline as by-products. The reaction of N-trimethylsilyl-N'-phenylurea with N-bromosuccinimide in THF produces, instead of expected N-phenylureidosuccinimide and bromotrimethylsilane, succinimide and N-(p-bromophenyl)-N-trimethylsilylurea which hydrolyzes to form (p-bromophenyl)urea.

  DOI：

  10.1023/b:rugc.0000016022.68917.bd
• 作为产物：
  描述：

  N-trimethylsilyl-N'-phenylurea 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 四氢呋喃 为溶剂， 反应 4.0h， 以64%的产率得到N-(p-bromophenyl)-N'-trimethylsilylurea
  参考文献：
  名称：

  Reaction of Phenylurea and N-Trimethylsilyl-N'-phenylurea with Vanadocene and N-Bromosuccinimide

  摘要：

  Phenylurea and N-trimethylsilyl-N'-phenylurea react with vanadocene (Cp2V) in toluene to,give N-(eta(5)-cyclopentadienyl)vanadio-N'-phenylurea as a major product and Cp2VN=C=O and aniline as by-products. The reaction of N-trimethylsilyl-N'-phenylurea with N-bromosuccinimide in THF produces, instead of expected N-phenylureidosuccinimide and bromotrimethylsilane, succinimide and N-(p-bromophenyl)-N-trimethylsilylurea which hydrolyzes to form (p-bromophenyl)urea.

  DOI：

  10.1023/b:rugc.0000016022.68917.bd

文献信息

• Reaction of Phenylurea and N-Trimethylsilyl-N'-phenylurea with Vanadocene and N-Bromosuccinimide
  作者：A. S. Gordetsov、S. V. Zimina、N. V. Kulagina、E. M. Moseeva、Yu. A. Kurskii、M. A. Lopatin

  DOI：10.1023/b:rugc.0000016022.68917.bd

  日期：2003.10

  Phenylurea and N-trimethylsilyl-N'-phenylurea react with vanadocene (Cp2V) in toluene to,give N-(eta(5)-cyclopentadienyl)vanadio-N'-phenylurea as a major product and Cp2VN=C=O and aniline as by-products. The reaction of N-trimethylsilyl-N'-phenylurea with N-bromosuccinimide in THF produces, instead of expected N-phenylureidosuccinimide and bromotrimethylsilane, succinimide and N-(p-bromophenyl)-N-trimethylsilylurea which hydrolyzes to form (p-bromophenyl)urea.