Bis-(4-methoxy-2,6-dimethyl-phenyl)-sulfoxid | 24586-86-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Bis-(4-methoxy-2,6-dimethyl-phenyl)-sulfoxid
• 英文别名: bis-(4-methoxy-2,6-dimethyl-phenyl)-sulfoxide；5-methoxy-2-(4-methoxy-2,6-dimethylphenyl)sulfinyl-1,3-dimethylbenzene
• CAS: 24586-86-5
• 化学式: C₁₈H₂₂O₃S
• 分子量: 318.437
• InChiKey: AIMQSGROLOBCGR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  22.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  35.53
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  Bis-(4-methoxy-2,6-dimethyl-phenyl)-sulfoxid 生成 Bis(2,6-dimethyl-4-methoxyphenyl)sulfide
  参考文献：
  名称：

  使用硫醇/三甲基甲硅烷基氯化物系统轻松还原亚砜和亚硫胺

  摘要：

  亚砜被发现用硫代硅烷 (PhSSiMe3) 缓慢脱氧，而在催化量的四丁基溴化铵的存在下，亚砜与硫代硅烷的脱氧反应顺利进行。出于制备目的，硫醇和三甲基氯硅烷的混合体系可成功用于亚砜的脱氧和亚砜的脱亚胺。

  DOI：

  10.1246/cl.1979.329
• 作为产物：
  描述：

  3,5-二甲基苯甲醚 在 三氯化铝 、 亚硫酸 作用下， 生成 Bis-(4-methoxy-2,6-dimethyl-phenyl)-sulfoxid
  参考文献：
  名称：

  Impact of Ambulance Diversion Policies in Urban, Suburban, and Rural Areas of Central Maryland

  摘要：

  Abstract. As a method to control patient flow to overburdened hospitals, effective emergency medical services (EMS) systems provide policies for ambulance diversion. The Maryland state EMS system supports two types of alert for general hospital use: red alert, aimed at limiting the delivery of patients who may require intensive care unit (ICU) admission, and yellow alert, aimed at preventing further overload of already overtaxed emergency departments (EDs). Objective: To examine the effect of those alert policies in different geographical environments, urban, suburban, and rural. Methods: Alert data for 23 hospitals in Central Maryland and ambulance arrival data for approximately 138,000 ambulance calls during calendar year 1996 were combined and analyzed. The impacts of diversion practices in the geographic areas were compared. Results: Red alert reduced volume in all patient acuity levels in all geographic areas by a statistically significant 0.4 patient/hr. Yellow alert diverted low‐acuity patients at the rate of 0.13 patient/hr (p < 0.001) in urban areas and at the rate of 0.16 patient/hr (p < 0.001) in suburban areas, but had minimal impact in the flow of patients in the rural environment. Conclusions: The ED diversion policy has some limited effect in preventing further patient volume in urban and suburban areas, but has virtually no impact in rural areas. However, an ICU diversion policy diverts patients of all acuities uniformly and inordinately diverts patients not likely to require ICU admissions while having only minimal impact on patients who do require ICU resources. The impact of red alert is uniform in all geographic areas. The impact and efficacy of ambulance diversion policies should be evaluated to ensure they are having the intended effect. While perhaps initially effective, the impact of alert policies may change over time.

  DOI：

  10.1111/j.1553-2712.2001.tb00546.x

文献信息

• NUMATA TATSUO; TOGO HIDEO; OAE SHIGERU, CHEM. LETT., 1979, NO 4, 329-332
  作者：NUMATA TATSUO、 TOGO HIDEO、 OAE SHIGERU

  DOI：——

  日期：——