6-(6-(6-(6-(6-carboxypyridin-2-yl)pyridin-2-yl)pyrimidin-4-yl)pyridin-2-yl)pyridine-2-carboxylic acid | 856887-78-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6-(6-(6-(6-(6-carboxypyridin-2-yl)pyridin-2-yl)pyrimidin-4-yl)pyridin-2-yl)pyridine-2-carboxylic acid
• 英文别名: 6-[6-[6-[6-(6-Carboxypyridin-2-yl)pyridin-2-yl]pyrimidin-4-yl]pyridin-2-yl]pyridine-2-carboxylic acid
• CAS: 856887-78-0
• 化学式: C₂₆H₁₆N₆O₄
• 分子量: 476.451
• InChiKey: GYJLNYULIDPXKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  36
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  152
• 氢给体数：
  2
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  6-(6-(6-(6-(6-carboxypyridin-2-yl)pyridin-2-yl)pyrimidin-4-yl)pyridin-2-yl)pyridine-2-carboxylic acid 在 氯化亚砜 作用下， 反应 24.0h， 生成 6-(6-(6-(6-(6-(chlorocarbonyl)pyridin-2-yl)pyridin-2-yl)pyrimidin-4-yl)pyridin-2-yl)pyridine-2-carbonyl chloride
  参考文献：
  名称：

  Preparation of new heterotopic ligands

  摘要：

  A six-step synthesis of two new heterotopic ligands, each possessing two unusual N,N,N,O tetradentate binding Subunits, has been developed. This work presents a particularly facile and rapid synthetic protocol for the preparation of these ligands, which one expected to act as useful components in inorganic self-assembly for the preparation of various types of complexes. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2005.03.131
• 作为产物：
  描述：

  2-(6-methylpyridin-2-yl)-6-(trimethylstannyl)pyridine 在 chromium(VI) oxide 、 四(三苯基膦)钯 、 硫酸 、 lithium chloride 作用下， 以 甲苯 为溶剂， 反应 24.0h， 生成 6-(6-(6-(6-(6-carboxypyridin-2-yl)pyridin-2-yl)pyrimidin-4-yl)pyridin-2-yl)pyridine-2-carboxylic acid
  参考文献：
  名称：

  Preparation of new heterotopic ligands

  摘要：

  A six-step synthesis of two new heterotopic ligands, each possessing two unusual N,N,N,O tetradentate binding Subunits, has been developed. This work presents a particularly facile and rapid synthetic protocol for the preparation of these ligands, which one expected to act as useful components in inorganic self-assembly for the preparation of various types of complexes. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2005.03.131