2,4-Bis-hydroxymethyl-5-methyl-phenol | 64032-91-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2,4-Bis-hydroxymethyl-5-methyl-phenol
• 英文别名: 2,4-Bis(hydroxymethyl)-5-methylphenol
• CAS: 64032-91-3
• 化学式: C₉H₁₂O₃
• 分子量: 168.192
• InChiKey: BMXGIBFDGDYWPK-UHFFFAOYSA-N

物化性质

• 熔点：
  118 °C
• 沸点：
  334.3±11.0 °C(Predicted)
• 密度：
  1.276±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 2,4-Bis-hydroxymethyl-5-methyl-phenol 生成 1,5-bis-hydroxymethyl-2-methoxy-4-methyl-benzene
  参考文献：
  名称：

  Reese, Chemische Berichte, 1953, vol. 86, p. 979,984

  摘要：

  DOI：
• 作为产物：
  描述：

  间甲酚 在 sodium hydroxide 、 聚合甲醛 作用下， 生成 2,4-Bis-hydroxymethyl-5-methyl-phenol
  参考文献：
  名称：

  Reese, Chemische Berichte, 1953, vol. 86, p. 979,984

  摘要：

  DOI：

文献信息

• Process for preparing para-hydroxybenzyl alcohol
  申请人：MITSUBISHI PETROCHEMICAL CO., LTD.

  公开号：EP0386639A1

  公开（公告）日：1990-09-12

  A process for preparing p-hydroxybenzyl alcohol or a derivative thereof comprising reacting a phenol and a formaldehyde source under a basic condition is disclosed, wherein the reaction is carried out in an alcoholic organic solvent in the presence of a crown ether. The process achieves high selectivity toward the para position without involving high cost.

  本发明公开了一种制备对羟基苯甲醇或其衍生物的工艺，该工艺包括在碱性条件下使苯酚和甲醛源发生反应，其中反应是在有冠醚存在的醇类有机溶剂中进行的。该工艺对对位具有高选择性，且成本不高。
• PROCESS FOR PARA-METHYLOLATING PHENOLIC COMPOUND
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP0485613A1

  公开（公告）日：1992-05-20

  A highly selective process for para-methylolating a phenolic compound, which comprises conducting the reaction of the phenolic compound with a formaldehyde source in an alcoholic organic solvent in the presence of a quaternary ammonium as the counter cation of a phenol anion.

  一种对甲醇化酚类化合物的高选择性工艺，包括在醇类有机溶剂中，在季铵作为酚阴离子的反阳离子存在下，使酚类化合物与甲醛源发生反应。
• Stable aqueous dispersions of hydrophilic phenolic resins having low xylenol and bisphenol-A content
  申请人：Boyer C. Peter

  公开号：US20060229415A1

  公开（公告）日：2006-10-12

  Storage stable aqueous dispersions of a heat-reactive hydrophilic phenolic resin (e.g., phenol/formaldehyde) are disclosed. The dispersions comprise a base resin that is the reaction product of an aromatic alcohol and an aldehyde, and an etherified resin component selected from the group consisting of an etherified phenol/aldehyde resin, an etherified cresol/aldehyde resin, and mixtures thereof. The dispersions further comprise a protective colloid (e.g., polyvinyl alcohol). The addition of the etherified resin component in an amount of at least about 20% by weight of the base resin provides storage stability, but does not adversely affect the desirable physical and chemical characteristics (e.g., chemical resistance) of end products made from such dispersions. Moreover, the dispersions of the present invention can avoid the use of etherified resin components derived from bisphenol-A and/or xylenols, which present heath concerns in food coating applications.

  本发明公开了一种热反应亲水性酚醛树脂（如酚/甲醛）的贮存稳定的水分散体。该分散体包括芳香醇和醛的反应产物基树脂，以及选自醚化苯酚/醛树脂、醚化甲酚/醛树脂及其混合物的醚化树脂组分。分散体还包括保护胶体（如聚乙烯醇）。醚化树脂成分的添加量至少为基础树脂重量的约 20%，可提供贮存稳定性，但不会对由此类分散体制成的最终产品的理想物理和化学特性（如耐化学性）产生不利影响。此外，本发明的分散体可以避免使用从双酚 A 和/或二甲苯醇中提取的醚化树脂成分，这些成分在食品涂料应用中会引起健康问题。
• High-molecular-weight novolak substituted phenolic resins and their preparation
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0032062B1

  公开（公告）日：1985-04-03
• STABLE AQUEOUS DISPERSIONS OF HYDROPHILIC PHENOLIC RESINS HAVING LOW XYLENOL AND BISPHENOL-A CONTENT
  申请人：Georgia-Pacific Chemicals LLC

  公开号：EP1874866B1

  公开（公告）日：2017-06-07