N-(4-t-butylbenzyl)-2-methyl-4,5,6,7-tetrahydro-3-(2H)-indazolecarboxamide | 124084-75-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-t-butylbenzyl)-2-methyl-4,5,6,7-tetrahydro-3-(2H)-indazolecarboxamide
• 英文别名: N-[(4-tert-butylphenyl)methyl]-2-methyl-4,5,6,7-tetrahydroindazole-3-carboxamide
• CAS: 124084-75-9
• 化学式: C₂₀H₂₇N₃O
• 分子量: 325.454
• InChiKey: YUDJGIWZDPPSSW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  46.9
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-甲基-4,5,6,7-四氢-2H-吲唑-3-羧酸 、 4-叔-丁基苄胺 在 氯化亚砜 、 三乙胺 作用下， 以 甲苯 为溶剂， 生成 N-(4-t-butylbenzyl)-2-methyl-4,5,6,7-tetrahydro-3-(2H)-indazolecarboxamide
  参考文献：
  名称：

  Pyrazole derivative and insecticidal and miticidal composition

  摘要：

  本发明揭示了一种新的吡唑衍生物以及一种含有该衍生物作为有效成分的杀虫或杀螨组合物。本发明的吡唑衍生物对于那些对传统杀虫剂表现出抗性的有害昆虫和螨类也具有良好的控制效果，而且由于其毒性较小且残留较少，不会干扰生态系统。

  公开号：

  US04861777A1

文献信息

• Pyrazole derivative and insecticidal and miticidal composition containing the derivative as active ingredient
  申请人：MITSUBISHI KASEI CORPORATION

  公开号：EP0307801A1

  公开（公告）日：1989-03-22

  A pyrazole derivative represented by the following formula (I): wherein R and R1 independently represent a hydrogen atom or a C1-C4 alkyl group; R2 represents a hydrogen atom, a C1-C4 alkyl group, a phenyl group or a benzyl group, which bonds to one of the nitrogen atoms of the pyrazole ring; R3 and R4 independently represent a hydrogen atom, a C1-C4 alkyl group or a phenyl group; R5 and R6 independently represent a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a C3-C6 cycloalkyl group, a C1-C4 alkoxy group, a C1-C4 halogenoalkoxy group,a C1-C4 hydroxyalkoxy group, a C2-C7 alkoxyalkoxy group, a nitro group, a trifluoromethyl group, a phenyl group, a phenoxy group, a benzyloxy group, an amino group, a C1-C4 alkylamino group, a C2-C8 dialkylamino group, a cyano group, a carboxyl group, a C2-C5 alkoxycarbonyl group, a C4-C7 cycloalkoxycarbonyl group, a C3-C9 alkoxyalkoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C3-C11 dialkylaminocarbonyl group, a piperidinocarbonyl group, a morpholinocarbonyl group, a trimethylsilyl group, a C1-C4 alkylthio group, a C1-C4 alkylsulfinyl group or a C1-C4 alkylsulfonyl group; " X represents an oxygen atom, a sulfur atom, NHO or NR7 wherein R7 represents a hydrogen atom or a C1-C4 alkyl group; Y represents an oxygen atom or a sulfur atom; m represents 1 or 2; and n represents 0 or 1, and an insecticidal or miticidal composition containing the derivative as the effective ingredient are disclosed. The pyrazole derivative of the present invention has an excellent controlling effect also against harmful insects and mites exhibiting resistance to conventional insecticides and does not disturb the ecosystem since it is less toxic and less residual.

  由下式(I)代表的吡唑衍生物： 其中 R 和 R1 独立地代表氢原子或 C1-C4 烷基；R2 代表氢原子、C1-C4 烷基、苯基或苄基，它们与吡唑环的一个氮原子结合；R3 和 R4 独立地代表氢原子、C1-C4 烷基或苯基；R5和R6各自代表氢原子、卤素原子、C1-C6烷基、C3-C6环烷基、C1-C4烷氧基、C1-C4卤代烷氧基、C1-C4羟基烷氧基、C2-C7烷氧基烷氧基、硝基、三氟甲基、苯基、苯氧基、苄氧基、氨基、C1-C4烷基氨基、C2-C8二烷基氨基、氰基、羧基、C2-C5 烷氧基羰基、C4-C7 环烷氧基羰基、C3-C9 烷氧基羰基、C2-C7 烷基氨基羰基、C3-C11 二烷基氨基羰基、哌啶基羰基、吗啉基羰基、三甲基硅基、C1-C4 烷硫基、C1-C4 烷基亚磺酰基或 C1-C4 烷基磺酰基；"X代表氧原子、硫原子、NHO或NR7，其中R7代表氢原子或C1-C4烷基；Y代表氧原子或硫原子；m代表1或2；n代表0或1，本发明公开了含有该衍生物作为有效成分的杀虫或杀螨剂组合物。 本发明的吡唑衍生物对传统杀虫剂具有抗性的有害昆虫和螨虫也有很好的防治效果，而且由于其毒性低、残留少，不会扰乱生态系统。
• OKADA, ITARU;OKUI, KANEHKO;NISIMATA, SIMPA;TAKAXASI, JODZI;FUKUTI, TOSIKI
  作者：OKADA, ITARU、OKUI, KANEHKO、NISIMATA, SIMPA、TAKAXASI, JODZI、FUKUTI, TOSIKI

  DOI：——

  日期：——
• US4861777A
  申请人：——

  公开号：US4861777A

  公开（公告）日：1989-08-29
• Pyrazole derivative and insecticidal and miticidal composition
  申请人：Mitsubishi Kasei Corporation

  公开号：US04861777A1

  公开（公告）日：1989-08-29

  A novel pyrazole derivative and an insecticidal or miticidal composition containing the derivative as the effective ingredient are disclosed. The pyrazole derivative of the present invention has an excellent controlling effect also against harmful insects and mites exhibiting resistance to conventional insecticides and does not disturb the ecosystem since it is less toxic and less residual.

  本发明揭示了一种新的吡唑衍生物以及一种含有该衍生物作为有效成分的杀虫或杀螨组合物。本发明的吡唑衍生物对于那些对传统杀虫剂表现出抗性的有害昆虫和螨类也具有良好的控制效果，而且由于其毒性较小且残留较少，不会干扰生态系统。