6-(4-benzyl-phenyl)-hexanoic acid | 102162-22-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-(4-benzyl-phenyl)-hexanoic acid
• 英文别名: 6-(4-Benzyl-phenyl)-hexansaeure；6-(4-Benzylphenyl)hexanoic acid
• CAS: 102162-22-1
• 化学式: C₁₉H₂₂O₂
• 分子量: 282.382
• InChiKey: FPCCGXCXDNATFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  甲基脂肪酰氯 在 氢氧化钾 、 三氯化铝 、 一水合肼 作用下， 反应 2.0h， 生成 6-(4-benzyl-phenyl)-hexanoic acid
  参考文献：
  名称：

  Macro Rings. XVI. The Synthesis and Side Chain Chemistry of [9]Paracyclophane¹

  摘要：

  DOI：

  10.1021/ja01545a050

文献信息

• SALTS OF PAROXETINE
  申请人：SMITHKLINE BEECHAM PLC

  公开号：EP1091958A1

  公开（公告）日：2001-04-18
• Method and Composition for Treating Inflammatory Disorders
  申请人：Meda AB

  公开号：US20160166508A1

  公开（公告）日：2016-06-16

  There is provided homogeneous pharmaceutical compositions for the treatment of inflammatory disorders comprising an antiinflammatory and/or antihistaminic active ingredient, a polar lipid liposome and a pharmaceutically-acceptable aqueous carrier.
• [EN] SALTS OF PAROXETINE<br/>[FR] SELS DE PAROXETINE
  申请人：SMITHKLINE BEECHAM PLC

  公开号：WO2000001692A1

  公开（公告）日：2000-01-13

  Piperidine compounds, processes for preparing them, pharmaceutical compositions comprising them and their use in therapy are disclosed.
• [EN] INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS<br/>[FR] INHIBITEURS DES ACTIVATEURS DU PLASMINOGENE DESTINES A REDUIRE LA MASSE CORPORELLE
  申请人：GENSET SA

  公开号：WO2003009871A2

  公开（公告）日：2003-02-06

  The present invention relates to the field of treating obesity related disorders. Obesity is a public health problem that is serious and widespread. Compounds, PAI Inhibitors, have been identified that reduces weight gain in animals. These compounds should be effective for reducing body mass and for treating obesity-related diseases and disorders. These obesity-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
• Macro Rings. XVI. The Synthesis and Side Chain Chemistry of [9]Paracyclophane¹
  作者：Donald J. Cram、M. Farid Antar

  DOI：10.1021/ja01545a050

  日期：1958.6