2-isopropylphenyllithium | 41285-22-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-isopropylphenyllithium
• CAS: 41285-22-7
• 化学式: C₉H₁₁Li
• 分子量: 126.127
• InChiKey: XNTMUPVTONHBCM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.23
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  2-isopropylphenyllithium 在 zinc dibromide 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 生成
  参考文献：
  名称：

  Stereostructure and thermodynamic stability of atropisomers of ortho-substituted 2,2′-diaryl-1,1′-binaphthalenes

  摘要：

  A series of ortho-substituted 2,2 '-aryl-1,1 '-binaphthalenes were prepared via Negishi arylation of 2,2 '-diiodo-1,1 '-binaphthalene in good to high yields (65-95%) as an equilibrium mixtures of up to three atropisomers (unlike,unlike, like,unlike, and like,like). Thermodynamic stability parameters of the atropisomers were evaluated from VT NMR spectra by regression analysis. The DFT parameters calculated using CAM-B3LYP functional comprising solvent permittivity were, apart from the toluene solution, which was expected to interact with the aromatic solute, in qualitative agreement with the experimental values. In the case of the ditolyl derivative, the population of the atropisomers was confirmed by CD spectroscopy via comparison with the population-weighted averaged spectrum computed using the M06 functional. X-ray structure analyses of particular atropisomers of the dianisyl, dianilinyl, and dinaphthyl derivatives are also presented and discussed. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2013.09.005
• 作为产物：
  描述：

  1-溴-2-异丙基苯 在 正丁基锂 作用下， 以 乙醚 、 正己烷 为溶剂， 反应 2.0h， 以93.4%的产率得到2-isopropylphenyllithium
  参考文献：
  名称：

  一种吡啶胺基IVB族双核金属配合物及其制备和应用

  摘要：

  本发明中的一种吡啶胺基IVB族双核金属配合物及其制备和应用，其结构如式Ⅰ所示：这种所述的吡啶胺基IVB族双核金属配合物，可以催化烯烃均聚、乙烯/α‑烯烃共聚，尤其是可以催化乙烯与高级α‑烯烃共聚。因双核金属催化剂的协同效应，使其催化活性相对较高，且催化聚合产物具有分子量高、双峰或宽峰分布的特点，共聚物共单体插入能力在45wt％以上，具有很好的工业应用前景。

  公开号：

  CN111848668B

文献信息

• Steric activation of chelate catalysts: efficient polyketone catalysts based on four-membered palladium(ii) diphosphine chelates
  作者：Stephen J. Dossett、Duncan F. Wass、Matthew D. Jones、Amy Gillon、A. Guy Orpen、James S. Fleming、Paul G. Pringle

  DOI：10.1039/b010063n

  日期：——

  Palladium(II) complexes of ligands of the type Ar2PCH2- PAr2 and Ar2PN(Me)PAr2 (Ar = ortho-substituted phenyl group) are very efficient catalysts for copolymerisation of CO and C2H4.

  类型为Ar2PCH2-PAr2和Ar2PN(Me)PAr2（其中Ar = 邻取代苯基）的二价钯配合物，是CO与C2H4共聚反应中非常高效的催化剂。
• Reactivity of <i>C</i> ₁ ‐Symmetric Heteroarylamido Hafnium Complexes towards Unsaturated Electrophilic Molecules: Development of New Families of Olefin Polymerization Catalysts
  作者：Pavel S. Kulyabin、Georgy P. Goryunov、Dmitry Y. Mladentsev、Dmitry V. Uborsky、Alexander Z. Voskoboynikov、Jo Ann M. Canich、John R. Hagadorn

  DOI：10.1002/chem.201901899

  日期：2019.8.6

  of the starting complexes, in some cases, results in the formation of two diastereoisomers after 1,1‐ or 1,2‐insertion. Most of the obtained novel complexes were shown to form active catalysts for olefin polymerization in the presence of MAO (methylaluminoxane). Thus, a new approach to the feasible and easy “late stage” modification of the precatalyst structure has been suggested; it can be performed

  通过将小的亲电不饱和分子插入配体的C Ar -Hf键，可以使具有[C，N，N]配体的杂芳基lam后茂金属功能化与先前未知的[O，N，N]，[N，N，N]，[O，N，N，N]和[N，N，N，N]类型的修饰配体形成的配合物。发现C 1在某些情况下，起始配合物的对称性会导致在插入1,1或1,2后形成两个非对映异构体。已显示大多数获得的新型配合物在MAO（甲基铝氧烷）存在下可形成烯烃聚合的活性催化剂。因此，已经提出了一种新的方法来对前催化剂结构进行可行且容易的“后期”修饰。它可以在聚合测试之前立即进行，而无需分离，甚至可以以高通量方式进行。
• Iron-catalyzed aryl- and alkenyllithiation of alkynes and its application to benzosilole synthesis
  作者：Eiji Shirakawa、Seiji Masui、Rintaro Narui、Ryo Watabe、Daiji Ikeda、Tamio Hayashi

  DOI：10.1039/c1cc11989c

  日期：——

  Phenyl- and vinyllithiums having an alkyl substituent at their ortho- and cis-position, respectively, readily added to alkynes in the presence of 5 mol% of Fe(acac)(3). The reaction of o-(trimethylsilyl)phenyllithium with alkynes gave benzosiloles through an addition-cyclization sequence.

  在5摩尔％Fe（acac）（3）的存在下，分别在邻位和顺位分别具有烷基取代基的苯基锂和乙烯基锂很容易添加到炔烃中。邻-（三甲基甲硅烷基）苯基锂与炔烃的反应通过加成环化序列得到苯并甲硅烷基。
• A short synthesis of (+)-β-lycorane by asymmetric conjugate addition cascade
  作者：Katsumi Nishimura、Naoshi Fukuyama、Tomohisa Yasuhara、Mitsuaki Yamashita、Takaaki Sumiyoshi、Yasutomo Yamamoto、Ken-ichi Yamada、Kiyoshi Tomioka

  DOI：10.1016/j.tet.2015.03.014

  日期：2015.9

  The chiral diether ligand-controlled asymmetric conjugate addition of organolithiums to nona-2,7-dienedioate and subsequent intramolecular conjugate addition of the enolate intermediate gave all-trans trisubstituted cyclohexanes with high ee and yields. Using this methodology, an efficient short asymmetric total synthesis of (+)-β-lycorane was accomplished in 33% overall yield through five steps from

  将有机锂的手性二醚配体控制的不对称共轭加成到壬二-2，7-二烯二酸酯上，随后分子内共轭加成烯醇盐中间体，得到具有高ee和高收率的全反式三取代环己烷。使用这种方法，通过二烯二酸酯的五个步骤，可以完成33％的总收率，有效地完成（+）-β-lycorane的短短不对称全合成。
• Pyridyldiamido Transition Metal Complexes, Production and Use Thereof
  申请人：ExxonMobil Chemical Patents Inc.

  公开号：US20150246982A1

  公开（公告）日：2015-09-03

  Pyridyldiamido transition metal complexes are disclosed for use in alkene polymerization to produce high melting point polyolefins.

  揭示了用于烯烃聚合的吡啶二胺基过渡金属配合物，以产生高熔点聚烯烃。