2,2'-(4-fluoro-1,2-phenylene)bis(2-propanol) | 146271-59-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2'-(4-fluoro-1,2-phenylene)bis(2-propanol)
• 英文别名: 2-[4-Fluoro-2-(2-hydroxypropan-2-yl)phenyl]propan-2-ol
• CAS: 146271-59-2
• 化学式: C₁₂H₁₇FO₂
• 分子量: 212.264
• InChiKey: ZGMPGQAPHQLRQA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,2'-(4-fluoro-1,2-phenylene)bis(2-propanol) 在 硫酸 作用下， 反应 1.0h， 生成 5-acetyl-6-fluoro-1,1,3,3-tetramethyl-1,3-dihydroisobenzofuran
  参考文献：
  名称：

  The diels-alder approach to musk odor type arenes

  摘要：

  The readily accessible 2-halogeno-1-trimethylsilyloxy-1,3-butadienes react smoothly with dimethyl acetylenedicarboxylate to afford 4-halophthalic esters. One of these cycloadducts was subsequently converted into heterocyclic analogues of phantolide like musk fragrances.

  DOI：

  10.1016/s0040-4020(01)88354-x
• 作为产物：
  描述：

  甲基氯化镁 、 4-氟邻苯二甲酸二甲酯 以 四氢呋喃 为溶剂， 反应 24.0h， 以71%的产率得到2,2'-(4-fluoro-1,2-phenylene)bis(2-propanol)
  参考文献：
  名称：

  The diels-alder approach to musk odor type arenes

  摘要：

  The readily accessible 2-halogeno-1-trimethylsilyloxy-1,3-butadienes react smoothly with dimethyl acetylenedicarboxylate to afford 4-halophthalic esters. One of these cycloadducts was subsequently converted into heterocyclic analogues of phantolide like musk fragrances.

  DOI：

  10.1016/s0040-4020(01)88354-x

文献信息

• PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, ELECTRONIC DEVICE, ACTIVE-LIGHT-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM AND MASK BLANK
  申请人：FUJIFILM Corporation

  公开号：US20170121437A1

  公开（公告）日：2017-05-04

  A pattern forming method includes forming a film using an actinic ray-sensitive or radiation-sensitive resin composition, exposing the film with active light or radiation, and developing the exposed film using a developer including an organic solvent, in which the actinic ray-sensitive or radiation-sensitive resin composition contains a compound having a partial structure represented by General Formula (I).
• The diels-alder approach to musk odor type arenes
  作者：Guo-qiang Shi、Sylvain Cottens、Sayed Ahmed Shiba、Schlosser Manfred

  DOI：10.1016/s0040-4020(01)88354-x

  日期：1992.11

  The readily accessible 2-halogeno-1-trimethylsilyloxy-1,3-butadienes react smoothly with dimethyl acetylenedicarboxylate to afford 4-halophthalic esters. One of these cycloadducts was subsequently converted into heterocyclic analogues of phantolide like musk fragrances.