2-[1H-benzimidazol-2-ylmethyl-[2-[bis(1H-benzimidazol-2-ylmethyl)amino]ethyl]amino]ethanol;nickel(2+);diperchlorate | 166099-73-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 2-[1H-benzimidazol-2-ylmethyl-[2-[bis(1H-benzimidazol-2-ylmethyl)amino]ethyl]amino]ethanol;nickel(2+);diperchlorate
• CAS: 166099-73-6
• 化学式: C₂₈H₃₀ClN₈NiO₅*ClO₄
• 分子量: 752.19
• InChiKey: PQFVLBNKYPOKHR-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  nickel(II) perchlorate hexahydrate 、 N-(2-Hydroxyethyl)-N,N',N'-tris(2-benzylimidazolylmethyl)-1,2-diaminoethane 以 乙醇 为溶剂， 生成 2-[1H-benzimidazol-2-ylmethyl-[2-[bis(1H-benzimidazol-2-ylmethyl)amino]ethyl]amino]ethanol;nickel(2+);diperchlorate
  参考文献：
  名称：

  Synthesis, properties, structure and bioactivity in vitro of mononuclear complexes of manganese and nickel with hydroxyethyltribenzimidazolylmethyl ethylene diamine

  摘要：

  Six novel mononuclear complexes, MnCI(2)L . H2O, Mn(SCN)(2)L . 2H(2)O, Mn(ClO2)(2)L . 2H(2)O, NiCl(2)L . 2H(2)O, Ni(SCN)(2)L . H2O, Ni(ClO4)(2)L (L = N-hydroxyethyl-N,N',N'-tribenzimidazolylmethyl ethylene diamine), have been synthesized and characterized. The UV-visible spectra of nickel complexes reveal that L is a weak field ligand. The ESR spectra indicate the asymmetric electronic environment of the manganese ion in its complex. The crystal and molecular structures of Ni(SCN)(2)L . H2O were determined by X-ray diffraction analysis. The nickel ions have distorted octahedral symmetry. The preliminary results of bioassay of the complexes showed that monomanganeses have antitumour activities in vitro.

  DOI：

  10.1016/0277-5387(94)00441-g