PhSCH2C(=CH2)CONH2 | 7519-05-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: PhSCH2C(=CH2)CONH2
• 英文别名: 2-(Phenyl-thio)acrylamide；2-phenylsulfanylprop-2-enamide
• CAS: 7519-05-3
• 化学式: C₉H₉NOS
• 分子量: 179.243
• InChiKey: WMDLCTBHKJJSDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  68.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-Chloro-2-(phenylthio)propionamide 在 三乙胺 作用下， 以 乙醚 为溶剂， 生成 PhSCH2C(=CH2)CONH2
  参考文献：
  名称：

  Structure of products of the addition of benzenesulfenyl chloride to acrylic acid derivatives

  摘要：

  DOI：

  10.1007/bf00846060
• 作为试剂：
  描述：

  双硫氧吡啶 、 (2S,3S,5R)-3-(tert-butyldiphenylsilanyloxy)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydrofuran-2-carboxylic acid 在 PhSCH2C(=CH2)CONH2 、 三苯基膦 作用下， 生成 1-[(2R,4S,5R)-4-[tert-butyl(diphenyl)silyl]oxy-5-pyridin-2-ylsulfanyloxolan-2-yl]-5-methylpyrimidine-2,4-dione 、 1'-thymine-(3'-O-t-butyl-diphenylsilyl-6'-carboxamido-2',5',6',7'-tetradeoxy-β-L-ribo-6'-ene-heptofuranosyl) 、 1'-thymine-(3'-O-t-butyl-diphenylsilyl-6'-carboxamido-2',5',6',7'-tetradeoxy-β-D-ribo-6'-ene-heptofuranosyl)
  参考文献：
  名称：

  Total Synthesis of the Thymidine Analogue of Sinefungin

  摘要：

  The carbon skeleton of ''Sinethymidin'' 4 was constructed by two radical coupling reaction. The first step was a coupling of the radical derived from 2 and the unsaturated amide 5. The olefin 6 thus obtained was added to the radical derived from the known N-hydroxy-2-thiopyridinone aspartic ester. ''Sinethymidin'', tested for its antileismanial effect, was devoid of activity.

  DOI：

  10.1080/15257779508009744

文献信息

• IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP2183215A2

  公开（公告）日：2010-05-12
• [EN] IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL<br/>[FR] COMPOSÉ IMIDATE ET SON UTILISATION DANS LA LUTTE CONTRE LES NUISIBLES
  申请人：SUMITOMO CHEMICAL CO

  公开号：WO2009014267A2

  公开（公告）日：2009-01-29

  There is provided a compound having an excellent controlling effect on arthropod pests represented by the formula (I-1): wherein Z represents an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; G represents a -A1-R1 group, etc.; X represents a -A2-R4 group, etc.; X0 represents a -A3-R6 group, etc.; or X and X0 are optionally taken together to form a -A2-T0-A3- group; M1 represents a -R8 group, etc.; A1, A2 and A3 independently represent an oxygen atom, etc.; R1 and R8 independently represents an optionally substituted C1-C20 chain hydrocarbon group, etc.; R4 and R6 independently represent an optionally substituted C1-C6 chain hydrocarbon group, etc.; and T0 represents an optionally substituted C2-C6 alkanediyl group.