Benzamide, N-[[(2-hydroxyphenyl)amino]thioxomethyl]-4-nitro- | 53501-22-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzamide, N-[[(2-hydroxyphenyl)amino]thioxomethyl]-4-nitro-
• 英文别名: N-[(2-hydroxyphenyl)carbamothioyl]-4-nitrobenzamide
• CAS: 53501-22-7
• 化学式: C₁₄H₁₁N₃O₄S
• 分子量: 317.325
• InChiKey: ZGWOREAIQWCTHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  139
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  对硝基苯甲酸 在 polyethylene glycol-600 (PEG-600) 氯化亚砜 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 生成 Benzamide, N-[[(2-hydroxyphenyl)amino]thioxomethyl]-4-nitro-
  参考文献：
  名称：

  Synthesis of N—Aroyl—N′—hydroxyethyl (Hydroxyphenyl) Thiourea Derivatives Under the Condition of Phase Transfer Catalysis

  摘要：

  Reaction of aminoethanol. or aminophenol with aroyl chloride and ammonium thiocyanate under the condition of solid-liquid phase transfer catalysis using polyethylene glycol-600 (PEG-600) as the catalyst yielded N-aroyl-N'-hydroxyethyl (hydroxy phenyl) thiourea derivatives.The products have been characterised on the basis of analytical and spectral(IR and 'H-NMR)data.

  DOI：

  10.1080/00397919808004862

文献信息

• SYNTHESIS AND BIOLOGICAL ACTIVITY OF<i>N</i>-AROYL-<i>N</i>′-SUBSTITUTED THIOUREA DERIVATIVES
  作者：You-Ming Zhang、Tai-Bao Wei、Li-Ming Gao

  DOI：10.1081/scc-100105882

  日期：2001.1

  A series of N-aroyl-N ' -substituted thiourea derivatives have been prepared in good to excellent yields under the condition of solid-liquid phase transfer catalysis using polyethylene glycol-400(PEG-400) as the catalyst. The products have been characterized on the basis of analytical and spectral (IR and H-1 NMR) data. The promoting effects of some compounds on wheat growth have been tested preliminary.
• Synthesis of N—Aroyl—N′—hydroxyethyl (Hydroxyphenyl) Thiourea Derivatives Under the Condition of Phase Transfer Catalysis
  作者：Taibao Wei、Youming Zhang

  DOI：10.1080/00397919808004862

  日期：1998.8

  Reaction of aminoethanol. or aminophenol with aroyl chloride and ammonium thiocyanate under the condition of solid-liquid phase transfer catalysis using polyethylene glycol-600 (PEG-600) as the catalyst yielded N-aroyl-N'-hydroxyethyl (hydroxy phenyl) thiourea derivatives.The products have been characterised on the basis of analytical and spectral(IR and 'H-NMR)data.