ethyl (E)-3-(4-benzoyl-3-hydroxyphenoxy)acrylate | 1226980-26-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ethyl (E)-3-(4-benzoyl-3-hydroxyphenoxy)acrylate
• 英文别名: ethyl (E)-3-(4-benzoyl-3-hydroxyphenoxy)prop-2-enoate
• CAS: 1226980-26-2
• 化学式: C₁₈H₁₆O₅
• 分子量: 312.322
• InChiKey: YPJXAMQZMYZPGL-ZHACJKMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2,4-二羟二苯甲酮 、 丙炔酸乙酯 在 三苯基膦 作用下， 以 甲苯 为溶剂， 以85%的产率得到ethyl (E)-3-(4-benzoyl-3-hydroxyphenoxy)acrylate
  参考文献：
  名称：

  An efficient chemoselective synthesis of O-vinylaryl systems using acetylenic esters and dihydroxybenzenes in the presence of triphenylphosphine or alkyl isocyanides

  摘要：

  The addition of 2,4-dihydroxyaceto(and benzo)phenone to propiolic ester is catalyzed by triphenylphosphine or tert-butyl isocyanide to form O-vinyl aryl derivatives in fairly good yields. (C) 2009 Robabeh Baharfar. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2009.10.007

文献信息

• An efficient chemoselective synthesis of O-vinylaryl systems using acetylenic esters and dihydroxybenzenes in the presence of triphenylphosphine or alkyl isocyanides
  作者：Robabeh Baharfar、Mohammad Javad Taghizadeh、Majid Ahmadian、Seyed Meysam Baghbanian

  DOI：10.1016/j.cclet.2009.10.007

  日期：2010.2

  The addition of 2,4-dihydroxyaceto(and benzo)phenone to propiolic ester is catalyzed by triphenylphosphine or tert-butyl isocyanide to form O-vinyl aryl derivatives in fairly good yields. (C) 2009 Robabeh Baharfar. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.