3-(3-chlorophenyl)-1,5-diphenylformazan | 88990-49-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(3-chlorophenyl)-1,5-diphenylformazan
• 英文别名: (E)-1-[(3-Chlorophenyl)(2-phenylhydrazinylidene)methyl]-2-phenyldiazene；N'-anilino-3-chloro-N-phenyliminobenzenecarboximidamide
• CAS: 88990-49-2
• 化学式: C₁₉H₁₅ClN₄
• 分子量: 334.808
• InChiKey: GMFJHCGCYSNUSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  49.1
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-(3-chlorophenyl)-1,5-diphenylformazan 在 thallium(III) acetate 作用下， 以 水 、 溶剂黄146 为溶剂， 以95%的产率得到
  参考文献：
  名称：

  Balakrishnan, R.; Srinivasan, Vangular S., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1983, vol. 22, # 8, p. 771 - 775

  摘要：

  DOI：
• 作为产物：
  描述：

  m-chlorobenzaldehyde phenylhydrazone 、 苯胺 在 盐酸 、 sodium nitrite 、 sodium acetate 、 sodium hydroxide 作用下， 以 水 、 甲醇 为溶剂， 反应 1.0h， 以87%的产率得到3-(3-chlorophenyl)-1,5-diphenylformazan
  参考文献：
  名称：

  Triphenyl verdazyl radicals’ reactivity with alkyne carboxylates as a synthetic route to 1-(phenyldiazenyl)isoquinoline-3,4-dicarboxylates

  摘要：

  A series of 1-(phenyldiazenyl)isoquinoline-3,4-dicarboxylates are synthesized by a unique reaction of triphenyl verdazyl radical with di-substituted electron deficient alkyne carboxylates. This transformation allows for the quick synthesis of this class of compounds in just three steps starting from a hydrazone. A radical mechanism that is consistent for the substitution patterns observed in the series of compounds made is proposed. The final product is obtained by a subsequent retro-Diels-Alder reaction. Crown Copyright (C) 2012 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.05.135

文献信息

• Triphenyl verdazyl radicals’ reactivity with alkyne carboxylates as a synthetic route to 1-(phenyldiazenyl)isoquinoline-3,4-dicarboxylates
  作者：Matthew Bancerz、Ernest Prack、Michael K. Georges

  DOI：10.1016/j.tetlet.2012.05.135

  日期：2012.8

  A series of 1-(phenyldiazenyl)isoquinoline-3,4-dicarboxylates are synthesized by a unique reaction of triphenyl verdazyl radical with di-substituted electron deficient alkyne carboxylates. This transformation allows for the quick synthesis of this class of compounds in just three steps starting from a hydrazone. A radical mechanism that is consistent for the substitution patterns observed in the series of compounds made is proposed. The final product is obtained by a subsequent retro-Diels-Alder reaction. Crown Copyright (C) 2012 Published by Elsevier Ltd. All rights reserved.
• Balakrishnan, R.; Srinivasan, Vangular S., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1983, vol. 22, # 8, p. 771 - 775
  作者：Balakrishnan, R.、Srinivasan, Vangular S.

  DOI：——

  日期：——