(o-tolylcarbamoyl-methylsulfanyl)-acetic acid ethyl ester | 511287-06-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (o-tolylcarbamoyl-methylsulfanyl)-acetic acid ethyl ester
• 英文别名: (o-Tolylcarbamoyl-methylmercapto)-essigsaeure-aethylester；Thiodiglykolsaeure-aethylester-o-toluidid；Ethyl 2-[2-(2-methylanilino)-2-oxoethyl]sulfanylacetate
• CAS: 511287-06-2
• 化学式: C₁₃H₁₇NO₃S
• 分子量: 267.349
• InChiKey: CXPZHAAQHORNPP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  80.7
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-chlorobenzylazide 、 (o-tolylcarbamoyl-methylsulfanyl)-acetic acid ethyl ester 、 氰乙酰胺 在 sodium 作用下， 以 异丙醇 为溶剂， 反应 6.0h， 以29%的产率得到8-aza-6-hydroxy-9H-9-(2'-chlorobenzyl)purin-2-yl-[4''-N-(o-methylphenyl)-3''-thiabutyramide]
  参考文献：
  名称：

  摘要：

  DOI：

  10.1023/a:1021222929824
• 作为产物：
  描述：

  邻甲苯胺 在 乙醇 、 氨 、 水 作用下， 生成 (o-tolylcarbamoyl-methylsulfanyl)-acetic acid ethyl ester
  参考文献：
  名称：

  Farm Wages and Living Standards in the Industrial Revolution: England,1670–1869

  摘要：

  This article calculates, nationally and by region, real wages for male English farm workers. Rural living costs are also estimated. Only in the 1820s did real day wages begin to increase from their level in the century before the industrial revolution, but by the 1860s they had climbed to 46 per cent above the average for 1670-1769. It is argued that these farm real wage gains will imply equivalent improvements in urban living standards. But, given what we know of land rents and returns on capital, farm wages entail no agricultural productivity gains before 1820, and modest gains thereafter.

  DOI：

  10.1111/1468-0289.00200

文献信息

• Farm Wages and Living Standards in the Industrial Revolution: England,1670–1869
  作者：Gregory Clark

  DOI：10.1111/1468-0289.00200

  日期：2001.8

  This article calculates, nationally and by region, real wages for male English farm workers. Rural living costs are also estimated. Only in the 1820s did real day wages begin to increase from their level in the century before the industrial revolution, but by the 1860s they had climbed to 46 per cent above the average for 1670-1769. It is argued that these farm real wage gains will imply equivalent improvements in urban living standards. But, given what we know of land rents and returns on capital, farm wages entail no agricultural productivity gains before 1820, and modest gains thereafter.
• ——
  作者：K. V. Kuleshov、A. V. Adamov、O. G. Rodin、V. P. Perevalov、A. R. El'man

  DOI：10.1023/a:1021222929824

  日期：——