N-(furan-2-ylmethyl)-4-(4-methoxyphenyl)aniline | 1448779-50-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(furan-2-ylmethyl)-4-(4-methoxyphenyl)aniline
• CAS: 1448779-50-7
• 化学式: C₁₈H₁₇NO₂
• 分子量: 279.338
• InChiKey: BUPCDESDITWSJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  34.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-甲氧基-联苯-4-胺 在 氢气 作用下， 以 乙醇 、 水 为溶剂， 20.0 ℃ 、101.33 kPa 条件下， 反应 28.0h， 生成 N-(furan-2-ylmethyl)-4-(4-methoxyphenyl)aniline
  参考文献：
  名称：

  One-pot Suzuki–Miyaura cross-coupling followed by reductive monoalkylation of the resulting nitro biaryl system utilizing Pd/C as catalyst

  摘要：

  Conditions for one-pot Suzuki-Miyaura cross-coupling between aryl boronic acids and bromo-nitrobenzene followed by reductive monoalkylation of the nitro functionality of the biaryl cross-coupling product utilizing hydrogen over Pd/C as the catalyst and aldehydes as alkylation agent are described. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.06.128

文献信息

• One-pot Suzuki–Miyaura cross-coupling followed by reductive monoalkylation of the resulting nitro biaryl system utilizing Pd/C as catalyst
  作者：Lena Pedersen、Mohamed F. Mady、Magne O. Sydnes

  DOI：10.1016/j.tetlet.2013.06.128

  日期：2013.8

  Conditions for one-pot Suzuki-Miyaura cross-coupling between aryl boronic acids and bromo-nitrobenzene followed by reductive monoalkylation of the nitro functionality of the biaryl cross-coupling product utilizing hydrogen over Pd/C as the catalyst and aldehydes as alkylation agent are described. (C) 2013 Elsevier Ltd. All rights reserved.